Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rebecca A Slotkowski"'
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268553 (2022)
Research registries are a powerful tool for boosting recruitment into clinical trials. However, little is known about how parents approach the decision to enroll their child in a pediatric participant research registry (PPRR). We conducted in-person,
Externí odkaz:
https://doaj.org/article/a22b090d0301430c9daeae688f310ccb
Publikováno v:
BMC pregnancy and childbirth. 22(1)
Background Previous studies suggest higher rates of caesarean section among women who identify as racial/ethnic minorities. The objective of this study was to understand factors contributing to differences in caesarean rates across racial and ethnic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414a5ad171ad277f12bc64b08bc5b9c9
https://pubmed.ncbi.nlm.nih.gov/35428241
https://pubmed.ncbi.nlm.nih.gov/35428241
Publikováno v:
PloS one. 17(5)
Research registries are a powerful tool for boosting recruitment into clinical trials. However, little is known about how parents approach the decision to enroll their child in a pediatric participant research registry (PPRR). We conducted in-person,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b9b4f94d534c43158cb7419c1c5818
https://pubmed.ncbi.nlm.nih.gov/35584152
https://pubmed.ncbi.nlm.nih.gov/35584152
Autor:
Scott P. Collins, Z. Zuo, J. Liu, Ryan T. Leenay, B. A. McGirr, Rebecca A. Slotkowski, Daphne Collias, Chase L. Beisel
Publikováno v:
eabb4054
Science advances
United States
Science advances
United States
CRISPR technologies have overwhelmingly relied on the Streptococcus pyogenes Cas9 (SpyCas9), with its consensus NGG and less preferred NAG and NGA protospacer-adjacent motifs (PAMs). Here, we report that SpyCas9 also recognizes sequences within an N(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a22e5579541767995a683ac8760154a
https://doi.org/10.1126/sciadv.abb4054
https://doi.org/10.1126/sciadv.abb4054
Autor:
Chunyu Liao, Steven R. Denny, Albert J. Keung, Chase L. Beisel, Fani Ttofali, Ryan T. Leenay, Taylor D Cecil, Rebecca A. Slotkowski
Publikováno v:
Nature communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
CRISPR-Cas systems inherently multiplex through CRISPR arrays—whether to defend against different invaders or mediate multi-target editing, regulation, imaging, or sensing. However, arrays remain difficult to generate due to their reoccurring repea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb5fe3c978d22995b28311d5f4c01cf
https://hdl.handle.net/10033/621909
https://hdl.handle.net/10033/621909
CRISPR-Cas systems naturally rely on CRISPR arrays to achieve immunity against multiple foreign invaders, where these arrays are also being utilized for multiplexed targeting as part of CRISPR technologies. However, CRISPR arrays have proven difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdad30f222760037623df2d501ab8d5b
https://doi.org/10.1016/bs.mie.2019.04.011
https://doi.org/10.1016/bs.mie.2019.04.011
Autor:
Jakob Weber, Rebecca A. Slotkowski, Axel A. Brakhage, Derek J. Mattern, Uffe Hasbro Mortensen, Vito Valiante, Christina Spuur Nødvig
Publikováno v:
ACS Synthetic Biology. 6:62-68
Filamentous fungi produce varieties of natural products even in a strain dependent manner. However, the genetic basis of chemical speciation between strains is still widely unknown. One example is trypacidin, a natural product of the opportunistic hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646e11ac36470a472e5ae3f8dc1eda7f
https://doi.org/10.1021/acssynbio.6b00203
https://doi.org/10.1021/acssynbio.6b00203
Autor:
Kenneth R. Maksimchuk, Ryan T. Leenay, Rodolphe Barrangou, Rebecca A. Slotkowski, Alexandra E. Briner, Ahmed A. Gomaa, Roma N. Agrawal, Chase L. Beisel
Publikováno v:
Molecular Cell. 62:137-147
CRISPR-Cas adaptive immune systems in prokaryotes boast a diversity of protein families and mechanisms of action, where most systems rely on protospacer-adjacent motifs (PAMs) for DNA target recognition. Here, we developed an in vivo, positive, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef687b7e978aefe67c1c89499f855cc5
https://doi.org/10.1016/j.molcel.2016.02.031
https://doi.org/10.1016/j.molcel.2016.02.031
Publikováno v:
RNA biology
The Class 2 Type V-A CRISPR effector protein Cas12a/Cpf1 has gained widespread attention in part because of the ease in achieving multiplexed genome editing, gene regulation, and DNA detection. Multiplexing derives from the ability of Cas12a alone to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8010a3c302ece799584b0283d6d85124
https://hdl.handle.net/10033/621601
https://hdl.handle.net/10033/621601
Autor:
Denny, Albert J. Keung, Cecil Td, Rebecca A. Slotkowski, Ryan T. Leenay, Chunyu Liao, Chase L. Beisel, Fani Ttofali
SUMMARYCRISPR-Cas systems inherently multiplex through their CRISPR arrays--whether to confer immunity against multiple invaders or by mediating multi-target editing, regulation, imaging, and sensing. However, arrays remain difficult to generate due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58388f1e12c5581a40dac62af0ff3884