Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Rebecca A Ihrie"'
Autor:
Mary-Bronwen L Chalkley, Rachel B Mersfelder, Maria Sundberg, Laura C Armstrong, Mustafa Sahin, Rebecca A Ihrie, Kevin C Ess
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292086 (2023)
Tuberous Sclerosis Complex (TSC) is a debilitating developmental disorder characterized by a variety of clinical manifestations. TSC is caused by mutations in the TSC1 or TSC2 genes, which encode the hamartin/tuberin proteins respectively. These prot
Externí odkaz:
https://doaj.org/article/d45f6b6c25b340218f4d2f8d48a9b3ea
Autor:
Nalin Leelatian, Justine Sinnaeve, Akshitkumar M Mistry, Sierra M Barone, Asa A Brockman, Kirsten E Diggins, Allison R Greenplate, Kyle D Weaver, Reid C Thompson, Lola B Chambless, Bret C Mobley, Rebecca A Ihrie, Jonathan M Irish
Publikováno v:
eLife, Vol 9 (2020)
A goal of cancer research is to reveal cell subsets linked to continuous clinical outcomes to generate new therapeutic and biomarker hypotheses. We introduce a machine learning algorithm, Risk Assessment Population IDentification (RAPID), that is uns
Externí odkaz:
https://doaj.org/article/4b0f2febcca2420290d9f64856a5a58a
Autor:
Jacquelyn A. Brown, Shannon L. Faley, Monika Judge, Patricia Ward, Rebecca A. Ihrie, Robert Carson, Laura Armstrong, Mustafa Sahin, John P. Wikswo, Kevin C. Ess, M. Diana Neely
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Tuberous sclerosis complex (TSC) is a multi-system genetic disease that causes benign tumors in the brain and other vital organs. The most debilitating symptoms result from involvement of the central nervous system and lead to a m
Externí odkaz:
https://doaj.org/article/302796375aee43128c1c645409209e15
Autor:
William E Haskins, Bethany L Zablotsky, Michael R Foret, Rebecca A Ihrie, Arturo eAlvarez-Buylla, Robert N Eisenman, Mitchel S Berger, Chin-Hsing Annie Lin
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Glioblastoma multiforme (GBM) is a clinically and pathologically heterogeneous brain tumor. Previous study of MRI-classified GBM has revealed a spatial relationship between Group 1 GBM (GBM1) and the subventricular zone (SVZ). The SVZ is an adult neu
Externí odkaz:
https://doaj.org/article/67e16c3ab848468c8fce5d108f2cf60f
Autor:
Shelly Beer, Anders Zetterberg, Rebecca A Ihrie, Ryan A McTaggart, Qiwei Yang, Nicole Bradon, Constadina Arvanitis, Laura D Attardi, Sandy Feng, Boris Ruebner, Robert D Cardiff, Dean W Felsher
Publikováno v:
PLoS Biology, Vol 2, Iss 11, p e332 (2004)
One of the enigmas in tumor biology is that different types of cancers are prevalent in different age groups. One possible explanation is that the ability of a specific oncogene to cause tumorigenesis in a particular cell type depends on epigenetic p
Externí odkaz:
https://doaj.org/article/da0a6891f4844b24ad898e2a6697d513
Publikováno v:
Seminars in Immunopathology. 45:3-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9c996f83feef86af93f43511199fb9e
https://doi.org/10.1007/s00281-022-00976-y
https://doi.org/10.1007/s00281-022-00976-y
Autor:
Todd Bartkowiak, Sierra M. Lima, Madeline J. Hayes, Akshitkumar M. Mistry, Asa A. Brockman, Justine Sinnaeve, Nalin Leelatian, Caroline E. Roe, Bret C. Mobley, Silky Chotai, Kyle D. Weaver, Reid C. Thompson, Lola B. Chambless, Rebecca A. Ihrie, Jonathan M. Irish
Publikováno v:
JCI Insight.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f761b187d461a40d26e013863084c18f
https://doi.org/10.1172/jci.insight.160652
https://doi.org/10.1172/jci.insight.160652
Autor:
Vivianne E. Morrison, Matthew G. Houpert, Jonathan B. Trapani, Asa A. Brockman, Philip J. Kingsley, Ketaki A. Katdare, Hillary M. Layden, Gabriela Nguena-Jones, Alexandra J. Trevisan, Kathleen A. Maguire-Zeiss, Lawrence J. Marnett, Gregory J. Bixa, Rebecca A. Ihrie, Bruce D. Carter
Microglia are the primary phagocytes in the central nervous system and are responsible for clearing dead cells generated during development or disease. The phagocytic process shapes the phenotype of the microglia, which affects the local environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3baf45fb2a4d1793a40a8c7ca21af12f
https://doi.org/10.1101/2023.03.03.531012
https://doi.org/10.1101/2023.03.03.531012
Autor:
Laura C. Geben, Asa A. Brockman, Mary Bronwen L. Chalkley, Serena R. Sweet, Julia E. Gallagher, Alexandra L. Scheuing, Richard B. Simerly, Kevin C. Ess, Jonathan M. Irish, Rebecca A. Ihrie
Publikováno v:
bioRxiv
A limiting factor in the regenerative capacity of the adult brain is the abundance and proliferative ability of neural stem cells (NSCs). Adult NSCs are derived from a subpopulation of embryonic NSCs that temporarily enter quiescence during mid-gesta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3198b90449be7eb2cf47c3dcc1efda3
https://europepmc.org/articles/PMC9948964/
https://europepmc.org/articles/PMC9948964/
Autor:
Asa A. Brockman, Rohit Khurana, Todd Bartkowiak, Portia L. Thomas, Shamilene Sivagnanam, Courtney B. Betts, Lisa M. Coussens, Christine M. Lovly, Jonathan M. Irish, Rebecca A. Ihrie
Publikováno v:
Cytometry Part B: Clinical Cytometry.
Cyclic immunohistochemistry (cycIHC) uses sequential rounds of colorimetric immunostaining and imaging for quantitative mapping of location and number of cells of interest. In addition, cycIHC benefits from the speed and simplicity of brightfield mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472aae633fa94e858832d85e7f522555
https://doi.org/10.1002/cyto.b.22114
https://doi.org/10.1002/cyto.b.22114