Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rebecca A Elsner"'
Autor:
Mark J Shlomchik, Claire Leibler, Shinu John, Shuchi Smita, Rachael Gordon, Sebastien Gingras, Sheldon Bastacky, Kensuke Miyake, Rebecca A Elsner, Kayla B Thomas, Stephen Joachim, Russell C Levack, Derrick Callahan, Ryutaro Fukui, Kevin M Nickerson
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/7e866731d48b4a219781ba0c08e5ac84
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1004976 (2015)
Lyme Disease caused by infection with Borrelia burgdorferi is an emerging infectious disease and already by far the most common vector-borne disease in the U.S. Similar to many other infections, infection with B. burgdorferi results in strong antibod
Externí odkaz:
https://doaj.org/article/293217c6fe9046ff958d31c9d148803e
Autor:
Nadine M. Weisel, Stephen M. Joachim, Shuchi Smita, Derrick Callahan, Rebecca A. Elsner, Laura J. Conter, Maria Chikina, Donna L. Farber, Florian J. Weisel, Mark J. Shlomchik
Publikováno v:
Nat Immunol
Memory B cells (MBC) protect the body from recurring infections. MBC differ from their naïve counterparts in many ways, but functional and surface marker differences are poorly characterized. In addition, though mice are the prevalent model for huma
Autor:
Rebecca A. Elsner, Mark J. Shlomchik
Publikováno v:
Immunity
Activated B cells participate in either extrafollicular (EF) or germinal center (GC) responses. Canonical responses are composed of a short wave of plasmablasts (PBs) arising from EF sites, followed by GC producing somatically mutated memory B cells
Autor:
Stacy G. Wendell, Daniel J. Wikenheiser, Steven J. Mullett, Thomas Winkler, Nikita Trivedi, Michael J. Jurczak, Greg M. Delgoffe, Laura J. Conter, Shuchi Smita, Mark J. Shlomchik, Florian Weisel, Stephen M. Joachim, Rebecca A. Elsner, Maria Chikina, William F. Hawse, Ashley V. Menk, Wei Luo
Publikováno v:
Nature Immunology. 21:331-342
Germinal center B cells (GCBCs) are critical for generating long-lived humoral immunity. How GCBCs meet the energetic challenge of rapid proliferation is poorly understood. Dividing lymphocytes typically rely on aerobic glycolysis over oxidative phos
Autor:
Claire Leibler, Rebecca A. Elsner, Khalil El Karoui, Chloé Samson, Allan Thiolat, Philippe Grimbert
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2019, 95, pp.774-786. ⟨10.1016/j.kint.2018.10.028⟩
Kidney International, Nature Publishing Group, 2019, 95, pp.774-786. ⟨10.1016/j.kint.2018.10.028⟩
There is an urgent need for therapeutic agents that target humoral alloimmunity in solid organ transplantation. This includes sensitized patients with preformed donor-specific human leukocyte antigen antibodies and patients who develop de novo donor-
Autor:
Florian J, Weisel, Steven J, Mullett, Rebecca A, Elsner, Ashley V, Menk, Nikita, Trivedi, Wei, Luo, Daniel, Wikenheiser, William F, Hawse, Maria, Chikina, Shuchi, Smita, Laura J, Conter, Stephen M, Joachim, Stacy G, Wendell, Michael J, Jurczak, Thomas H, Winkler, Greg M, Delgoffe, Mark J, Shlomchik
Publikováno v:
Cell Mol Immunol
Germinal center B cells (GCBCs) are critical for generating long-lived humoral immunity. How GCBCs meet the energetic challenge of rapid proliferation is poorly understood. Dividing lymphocytes typically rely on aerobic glycolysis over oxidative phos
Autor:
Rebecca A. Elsner, Mark J. Shlomchik
Publikováno v:
SSRN Electronic Journal.
Germinal centers (GC) are crucial for the formation of long-lived humoral immunity. Many pathogens suppress GC, including Salmonella enterica serovar Typhimurium (STm), but the mechanisms driving suppression remain unknown. Using a mouse model of inf
Publikováno v:
Infection and immunity, vol 83, iss 1
CD4 T cells are crucial for enhancing B cell-mediated immunity, supporting the induction of high-affinity, class-switched antibody responses, long-lived plasma cells, and memory B cells. Previous studies showed that the immune response to Borrelia bu