Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebecca A Dabbs"'
Autor:
Tate Oulton, Joshua Obiero, Isabel Rodriguez, Isaac Ssewanyana, Rebecca A Dabbs, Christine M Bachman, Bryan Greenhouse, Chris Drakeley, Phil L Felgner, Will Stone, Kevin K A Tetteh
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273106 (2022)
The evaluation of protein antigens as putative serologic biomarkers of infection has increasingly shifted to high-throughput, multiplex approaches such as the protein microarray. In vitro transcription/translation (IVTT) systems-a similarly high-thro
Externí odkaz:
https://doaj.org/article/5061e8e9fd41449b8f4ce5889d16bc64
Autor:
Barnabas G. Williams, Lloyd D. W. King, David Pulido, Doris Quinkert, Amelia M. Lias, Sarah E. Silk, Robert J. Ragotte, Hannah Davies, Jordan R. Barrett, Kirsty McHugh, Cassandra A. Rigby, Daniel G. W. Alanine, Lea Barfod, Michael W. Shea, Li An Cowley, Rebecca A. Dabbs, David J. Pattinson, Alexander D. Douglas, Oliver R. Lyth, Joseph J. Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M. Christen, Amy R. Noe, Randall S. MacGill, C. Richter King, Ashley J. Birkett, Lorraine A. Soisson, Katherine Skinner, Kazutoyo Miura, Carole A. Long, Matthew K. Higgins, Simon J. Draper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Reticulocyte-binding protein homologue 5 (RH5), a leading blood-stage Plasmodium falciparum malaria vaccine target, interacts with cysteine-rich protective antigen (CyRPA) and RH5-interacting protein (RIPR) to form an essential heterotrimeri
Externí odkaz:
https://doaj.org/article/c0357f954cd04ff984155d03439a386e
Autor:
Rebecca A Dabbs, Mark R Wilson
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86989 (2014)
Clusterin was the first described secreted mammalian chaperone and is implicated as being a key player in both intra- and extracellular proteostasis. Its unique combination of structural features and biological chaperone activity has, however, previo
Externí odkaz:
https://doaj.org/article/d7f04b9056474b29bd65fa46ead77b83
Autor:
David M. P. De Oliveira, Lauren Hartley-Tassell, Arun Everest-Dass, Christopher J. Day, Rebecca A. Dabbs, Thomas Ve, Bostjan Kobe, Victor Nizet, Nicolle H. Packer, Mark J. Walker, Michael P. Jennings, Martina L. Sanderson-Smith
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Streptococcus pyogenes (group A streptococcus [GAS]) is responsible for over 500,000 deaths worldwide each year. The highly virulent M1T1 GAS clone is one of the most frequently isolated serotypes from streptococcal pharyngitis and invasive
Externí odkaz:
https://doaj.org/article/a691605b870247b8b88dbc858307280f
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
The first described and best known mammalian secreted chaperone, abundant in human blood, is clusterin. Recent independent studies are now exploring the potential use of clusterin as a therapeutic in a variety of disease contexts. In the past, the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcfaeb92464015788ff9f6716f6f456
http://link.springer.com/article/10.1038/s41598-020-70990-3
http://link.springer.com/article/10.1038/s41598-020-70990-3
Autor:
Yvonne Azasi, Deepak Gaur, Shannon K. Gallagher, Carole A. Long, Rebecca A. Dabbs, Ababacar Diouf, Simon J. Draper, Michael P. Fay, Kazutoyo Miura, Louis H. Miller, Syed Yusuf Mian, David L. Narum, Jing Jin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Plasmodium invasion of red blood cells involves malaria proteins, such as reticulocyte-binding protein homolog 5 (RH5), RH5 interacting protein (RIPR), cysteine-rich protective antigen (CyRPA), apical membrane antigen 1 (AMA1) and rhoptry neck protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfc94259ab811faf95fceea8c4b3696
http://link.springer.com/article/10.1038/s41598-020-67877-8
http://link.springer.com/article/10.1038/s41598-020-67877-8
Autor:
Kevin K. A. Tetteh, Isaac Ssewanyana, Bryan Greenhouse, Joshua M. Obiero, Tate Oulton, Phil L. Felgner, Chris Drakeley, Isabel Rodriguez, Rebecca A. Dabbs, Will Stone
The evaluation of protein antigens as putative serologic biomarkers of infection has increasingly shifted to high-throughput, multiplex approaches such as the protein microarray. In vitro transcription/translation (IVTT) systems – a similarly high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8b52239069d6d67629b5780bdfa82d
https://doi.org/10.1101/2020.12.15.422854
https://doi.org/10.1101/2020.12.15.422854
Autor:
Persephone Borrow, Carolyn M. Nielsen, Angela M. Minassian, Lea Barfod, Kazutoyo Miura, Todd Bradley, Susanne E. Doeleman, Barton F. Haynes, Sean C. Elias, Rebecca A. Dabbs, Ruth O. Payne, Jordan R. Barrett, Ababacar Diouf, Martino Bardelli, Ane Ogbe, Carole A. Long, Sarah E. Silk, Yue Chen, Isabela Pedroza-Pacheco, Simon J. Draper
Publikováno v:
Cell Reports Medicine
Summary Interactions between B cells and CD4+ T follicular helper (Tfh) cells are key determinants of humoral responses. Using samples from clinical trials performed with the malaria vaccine candidate antigen Plasmodium falciparum merozoite protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8227444292ba17345939243c7f25aaae
https://doi.org/10.1016/j.xcrm.2021.100207
https://doi.org/10.1016/j.xcrm.2021.100207
Autor:
Jing, Jin, Richard D, Tarrant, Emma J, Bolam, Philip, Angell-Manning, Max, Soegaard, David J, Pattinson, Pawan, Dulal, Sarah E, Silk, Jennifer M, Marshall, Rebecca A, Dabbs, Fay L, Nugent, Jordan R, Barrett, Kathryn A, Hjerrild, Lars, Poulsen, Thomas, Jørgensen, Tanja, Brenner, Ioana N, Baleanu, Helena M, Parracho, Abdessamad, Tahiri-Alaoui, Gary, Whale, Sarah, Moyle, Ruth O, Payne, Angela M, Minassian, Matthew K, Higgins, Frank J, Detmers, Alison M, Lawrie, Alexander D, Douglas, Robert, Smith, Willem A, de Jongh, Eleanor, Berrie, Rebecca, Ashfield, Simon J, Draper
Publikováno v:
NPJ Vaccines
Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is a leading asexual blood-stage vaccine candidate for malaria. In preparation for clinical trials, a full-length PfRH5 protein vaccine called “RH5.1” was produced as a soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f50c213b127b11b847cd96aa8220f18
https://pubmed.ncbi.nlm.nih.gov/30131879
https://pubmed.ncbi.nlm.nih.gov/30131879
Publikováno v:
Journal of Molecular Biology. 421:499-516
Extracellular protein misfolding and aggregation underlie many of the most serious amyloidoses including Alzheimer's disease, spongiform encephalopathies and type II diabetes. Despite this, protein homeostasis (proteostasis) research has largely focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45aaebe0263b7e0bf62584b021186f95
https://doi.org/10.1016/j.jmb.2012.01.004
https://doi.org/10.1016/j.jmb.2012.01.004