Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rebecca A, Sager"'
Autor:
Sarah J. Backe, Rebecca A. Sager, Jennifer A. Heritz, Laura A. Wengert, Katherine A. Meluni, Xavier Aran-Guiu, Barry Panaretou, Mark R. Woodford, Chrisostomos Prodromou, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113672- (2024)
Externí odkaz:
https://doaj.org/article/9fda5e1eb2a7419281fc9e680ef89a78
Autor:
Sarah J. Backe, Rebecca A. Sager, Jennifer A. Heritz, Laura A. Wengert, Katherine A. Meluni, Xavier Aran-Guiu, Barry Panaretou, Mark R. Woodford, Chrisostomos Prodromou, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112807- (2023)
Summary: Cellular homeostasis relies on both the chaperoning of proteins and the intracellular degradation system that delivers cytoplasmic constituents to the lysosome, a process known as autophagy. The crosstalk between these processes and their un
Externí odkaz:
https://doaj.org/article/4372f2b85d70407f912e42e25ea43467
Autor:
Rebecca A. Sager, Farzana Khan, Lorenzo Toneatto, SarahBeth D. Votra, Sarah J. Backe, Mark R. Woodford, Mehdi Mollapour, Dimitra Bourboulia
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The molecular chaperone Heat Shock Protein-90 (Hsp90) is known to interact with over 300 client proteins as well as regulatory factors (eg. nucleotide and proteins) that facilitate execution of its role as a chaperone and, ultimately, client protein
Externí odkaz:
https://doaj.org/article/6e665a91972e47c9bdf7bdf90d269459
Autor:
Sarah J. Backe, Rebecca A. Sager, Katherine A. Meluni, Mark R. Woodford, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 928 (2022)
Heat shock protein-90 (Hsp90) is an ATP-dependent molecular chaperone that is tightly regulated by a group of proteins termed co-chaperones. This chaperone system is essential for the stabilization and activation of many key signaling proteins. Recen
Externí odkaz:
https://doaj.org/article/318844d88a05455f8a84a8a3e70f9abe
Autor:
Natela Dushukyan, Diana M. Dunn, Rebecca A. Sager, Mark R. Woodford, David R. Loiselle, Michael Daneshvar, Alexander J. Baker-Williams, John D. Chisholm, Andrew W. Truman, Cara K. Vaughan, Timothy A. Haystead, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1883-1895 (2017)
Summary: The serine/threonine protein phosphatase 5 (PP5) regulates multiple cellular signaling networks. A number of cellular factors, including heat shock protein 90 (Hsp90), promote the activation of PP5. However, it is unclear whether post-transl
Externí odkaz:
https://doaj.org/article/1fd7653e1f7244c682e707f46ef9dd06
Autor:
Rebecca A. Sager, Mark R. Woodford, Sarah J. Backe, Alan M. Makedon, Alexander J. Baker-Williams, Bryanna T. DiGregorio, David R. Loiselle, Timothy A. Haystead, Natasha E. Zachara, Chrisostomos Prodromou, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1344-1356.e5 (2019)
Summary: The molecular chaperone Hsp90 stabilizes and activates client proteins. Co-chaperones and post-translational modifications tightly regulate Hsp90 function and consequently lead to activation of clients. However, it is unclear whether this pr
Externí odkaz:
https://doaj.org/article/de66c6bb8ecb4bfabba4d27f34f19f26
Autor:
Elham Ahanin, Rebecca A. Sager, Sarah J. Backe, Natela Dushukyan, Michael Daneshvar, Gennady Bratslavsky, John Chisholm, Mark R. Woodford, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159c3488fc813f49523e96a1ec8b0071
https://doi.org/10.1097/ju.0000000000003215.09
https://doi.org/10.1097/ju.0000000000003215.09
Autor:
Rebecca A. Sager, Sarah J. Backe, Diana M. Dunn, Jennifer A. Heritz, Elham Ahanin, Natela Dushukyan, Barry Panaretou, Gennady Bratslavsky, Mark R. Woodford, Dimitra Bourboulia, Mehdi Mollapour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39be4d747f4c3b9ac7a6aff76a7121c3
https://doi.org/10.2139/ssrn.4352019
https://doi.org/10.2139/ssrn.4352019
Autor:
Sarah J, Backe, Mark R, Woodford, Elham, Ahanin, Rebecca A, Sager, Dimitra, Bourboulia, Mehdi, Mollapour
Publikováno v:
Subcellular Biochemistry ISBN: 9783031147395
Subcell Biochem
Subcell Biochem
Posttranslational modifications (PTMs) regulate myriad cellular processes by modulating protein function and protein-protein interaction. Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone whose activity is responsible for the stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20f7db295657147cd881afc3131eb8b
https://doi.org/10.1007/978-3-031-14740-1_11
https://doi.org/10.1007/978-3-031-14740-1_11
Autor:
Rebecca A. Sager, Gennady Bratslavsky, Mark R. Woodford, Mehdi Mollapour, Sarah J. Backe, Dimitra Bourboulia
Publikováno v:
Urol Oncol
Birt-Hogg-Dubé (BHD) and tuberous sclerosis (TS) syndromes share many clinical features. These two diseases display distinct histologic subtypes of renal tumors: chromophobe renal cell carcinoma and renal angiomyolipoma, respectively. Early work sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25abbf182d34e24152b4d5bcc47608f
https://doi.org/10.1016/j.urolonc.2020.03.016
https://doi.org/10.1016/j.urolonc.2020.03.016