Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rebecca Suttmann"'
Autor:
Mark R. Lackner, Craig Cummings, Steven Gendreau, Ling-Yuh Huw, Rebecca Suttmann, May M.Y. Liang-Chu, Mamie Yu, Junko Aimi, Charles Baudo, Vidushi Kapoor, Kathryn E. Yoh, Jill M. Spoerke, Ching-Wei Chang, Xiaoji Chen
Baseline and on-treatment CNV landscapes of patients treated with pictilisib. Somatic variants significantly increased in EOT compared to baseline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d80164377efcfe3f9999742397c3b6c
https://doi.org/10.1158/1078-0432.22474472.v1
https://doi.org/10.1158/1078-0432.22474472.v1
Autor:
Mark R. Lackner, Craig Cummings, Steven Gendreau, Ling-Yuh Huw, Rebecca Suttmann, May M.Y. Liang-Chu, Mamie Yu, Junko Aimi, Charles Baudo, Vidushi Kapoor, Kathryn E. Yoh, Jill M. Spoerke, Ching-Wei Chang, Xiaoji Chen
Purpose:We developed a method to monitor copy number variations (CNV) in plasma cell-free DNA (cfDNA) from patients with metastatic squamous non–small cell lung cancer (NSCLC). We aimed to explore the association between tumor-derived cfDNA and cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eb86c6dd4fbb499599b927038e7b6c
https://doi.org/10.1158/1078-0432.c.6528800
https://doi.org/10.1158/1078-0432.c.6528800
Autor:
Craig Cummings, Kathryn E. Yoh, Ching-Wei Chang, Rebecca Suttmann, Jill M. Spoerke, Junko Aimi, Vidushi Kapoor, Steven Gendreau, Charles D. Baudo, Mark R. Lackner, Mamie Yu, Ling-Yuh Huw, Xiaoji Chen, May M. Y. Liang-Chu
Publikováno v:
Clinical Cancer Research. 25:2254-2263
Purpose: We developed a method to monitor copy number variations (CNV) in plasma cell-free DNA (cfDNA) from patients with metastatic squamous non–small cell lung cancer (NSCLC). We aimed to explore the association between tumor-derived cfDNA and cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef6f40b0d67ed67b72d879ebf5f6cde
https://doi.org/10.1158/1078-0432.ccr-18-1593
https://doi.org/10.1158/1078-0432.ccr-18-1593
Autor:
Christopher Lowe, Mike Reichelt, Shilpi Mahajan, Trung Nguy, Rachel Melendez, Jenny Yang, Yijin Li, Vicki Plaks, Kathryn E. Yoh, Rebecca Suttmann, Wenfeng Xu, Jane Ruppel, Luciana Molinero
Publikováno v:
Journal of immunological methods. 490
Extracellular vesicles (EVs) are gaining considerable traction within the liquid biopsy arena, as carriers of information from cells in distant sites that may not be accessible for biopsy. Therefore, there is a need to develop methods to enrich for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de72aa89d27e3997dc3557d93a6632fd
https://pubmed.ncbi.nlm.nih.gov/33242493
https://pubmed.ncbi.nlm.nih.gov/33242493
Autor:
Eric Selva, Paul Hofman, Véronique Hofman, Wei Yu, Elodie Long-Mira, Marius Ilie, Catherine Butori, Edith Szafer-Glusman, David S. Shames, Salomé Lalvée, Julien Fayada, Rebecca Suttmann, Walter C. Darbonne, Charles-Hugo Marquette, Elizabeth Punnoose
Publikováno v:
Oncotarget
// Marius Ilie 1, 2, * , Edith Szafer-Glusman 3, * , Veronique Hofman 1, 2, 4 , Elodie Long-Mira 1, 2 , Rebecca Suttmann 3 , Walter Darbonne 3 , Catherine Butori 1 , Salome Lalvee 1 , Julien Fayada 4 , Eric Selva 4 , Wei Yu 3 , Charles-Hugo Marquette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f44872cc77cb1bfa0898f2160096806
https://pubmed.ncbi.nlm.nih.gov/28212540
https://pubmed.ncbi.nlm.nih.gov/28212540
Autor:
Charles D. Baudo, Rebecca Suttmann, David S. Shames, Samir Seshadri, Teiko Sumiyoshi, Mark R. Lackner, An D. Do, Shih-Min A. Huang, Xiaoji Chen
Publikováno v:
Cancer Research. 78:5571-5571
Gastric cancer (GC) is the fifth most common cancer diagnosis with roughly 60% of patients with metastatic disease. Tumor heterogeneity represents a major challenge to personalized cancer therapy. Intratumor heterogeneity can result in missing critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a485a180497387d76e3f84b70807d9b6
https://doi.org/10.1158/1538-7445.am2018-5571
https://doi.org/10.1158/1538-7445.am2018-5571
Autor:
Francisco Xavier Talamas, Brian Wong, Simon W. Lee, Terrence Z. Cai, Pam S. Olson, Kyung Song, Mohammad Hekmat-Nejad, Anthony M. Manning, Ronald J. Hill, Jim W. Barnett, Rebecca Suttmann, Kelly D. Thompson, Sue Jin
Publikováno v:
Molecular Immunology. 46:1458-1466
IRAK-1 and IRAK-4 are protein kinases that mediate signaling by Toll/IL1/Plant R (TIR) domain-containing receptors including the IL-1, IL-18, and Toll-like receptors (TLRs). Although well studied in mouse systems, the mechanism by which they function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d430aac48fb332f3957fca412838e1
https://doi.org/10.1016/j.molimm.2008.12.012
https://doi.org/10.1016/j.molimm.2008.12.012
Autor:
Yong-Nam Kim, Stanford L. Peng, Anthony M. Manning, Joseph Dal Porto, Karim Dabbagh, Ronald J. Hill, Mary Welch, Kyung Song, Tanja S. Zabka, Ching Li, Dee Aud, Rebecca Suttmann, David Leaffer, Kung-ching Chang, Eva Papp, Brian Wong, Deborah Phippard, David Michael Goldstein, Richard T. Roberts
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 327:610-619
P38alpha is a protein kinase that regulates the expression of inflammatory cytokines, suggesting a role in the pathogenesis of diseases such as rheumatoid arthritis (RA) or systemic lupus erythematosus. Here, we describe the preclinical pharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5502518251ceeb1bab20275edd3fd6e3
https://doi.org/10.1124/jpet.108.139006
https://doi.org/10.1124/jpet.108.139006
Autor:
Charles Alois Dvorak, Francisco Javier Lopez-Tapia, Xiaojun Huang, Brad Loe, Debra A. Cockayne, William L. Fitch, Scott Broadbent, Berger Jacob, Christine E. Brotherton-Pleiss, Keith A. M. Walker, Rebecca Suttmann, David L. Bourdet, Lee Edwin Lowrie, Shelley K. Gleason, Dov Nitzan, Paul J. Wagner, Jiang Zhu, Zhao Shu-Hai, Fernando Padilla, André Alker, Joanie Caroon, Deborah Phippard, Alam Jahangir, Pankaj D. Rege
Publikováno v:
Journal of medicinal chemistry. 58(21)
Identification of singleton P2X7 inhibitor 1 from HTS gave a pharmacophore that eventually turned into potential clinical candidates 17 and 19. During development, a number of issues were successfully addressed, such as metabolic stability, plasma st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e880f027ef8eadeaef6f8cc77b4f99c
https://pubmed.ncbi.nlm.nih.gov/26460788
https://pubmed.ncbi.nlm.nih.gov/26460788
Publikováno v:
Journal of Biological Chemistry. 267:257-260
4'-Azidothymidine (ADRT) is a novel nucleoside analog, that selectively inhibits human immunodeficiency virus replication in human lymphocytes. Unlike the dideoxyribonucleoside analogs and 3'-azido-2',3'-dideoxythymidine (AZT), ADRT retains the 3'-hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e2adfe74476943ec03982c5de8c38c6
https://doi.org/10.1016/s0021-9258(18)48487-6
https://doi.org/10.1016/s0021-9258(18)48487-6