Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Rebecca, Schulman"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Molecular biosensors that accurately measure protein concentrations without external equipment are critical for solving numerous problems in diagnostics and therapeutics. Modularly transducing the binding of protein antibodies, protein switc
Externí odkaz:
https://doaj.org/article/a4d9604f50f246d4a1188d8f1ec761f6
Autor:
Ruohong Shi, Kuan-Lin Chen, Joshua Fern, Siming Deng, Yixin Liu, Dominic Scalise, Qi Huang, Noah J. Cowan, David H. Gracias, Rebecca Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The ability to transform matter between numerous physical states or shapes without wires or external devices is a major challenge for robotics and materials design. Organisms can transform their shapes using biomolecules carrying specific in
Externí odkaz:
https://doaj.org/article/e701545ec5ed49b1805c7ba4f5f40361
Autor:
Moshe Rubanov, Joshua Cole, Heon-Joon Lee, Leandro G Soto Cordova, Zachary Chen, Elia Gonzalez, Rebecca Schulman
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0295923 (2024)
DNA-functionalized hydrogels are capable of sensing oligonucleotides, proteins, and small molecules, and specific DNA sequences sensed in the hydrogels' environment can induce changes in these hydrogels' shape and fluorescence. Fabricating DNA-functi
Externí odkaz:
https://doaj.org/article/946bced686a54fbd802c354a4875ff8c
Growth and site-specific organization of micron-scale biomolecular devices on living mammalian cells
Autor:
Sisi Jia, Siew Cheng Phua, Yuta Nihongaki, Yizeng Li, Michael Pacella, Yi Li, Abdul M. Mohammed, Sean Sun, Takanari Inoue, Rebecca Schulman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Mesoscale molecular assemblies on the cell surface integrate information and amplify signals. Here the authors integrate DNA nanotubes in a controlled manner with mammalian cells to act as sheer stress meters.
Externí odkaz:
https://doaj.org/article/69fc8bc374494994b279afe01cbb6a3f
Publikováno v:
Royal Society Open Science, Vol 9, Iss 8 (2022)
In multi-cellular organisms, cells and tissues coordinate biochemical signal propagation across length scales spanning micrometres to metres. Designing synthetic materials with similar capacities for coordinated signal propagation could allow these s
Externí odkaz:
https://doaj.org/article/0288e349eac24c3b8257765f0f4b2a31
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Gaining control over crystallization processes is challenging. Herein, the authors describe a protocol for the controlled growth of DNA nanotubes by feedback regulation: the coupling of a reversible bimolecular monomer buffering reaction delivers the
Externí odkaz:
https://doaj.org/article/7694235319dd4daeba447ac6fd30051b
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18753-18761 (2018)
Externí odkaz:
https://doaj.org/article/46d10f9f06b14c699eb671333c7a5136
Autor:
Joshua Fern, Rebecca Schulman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Materials which change shape in response to a trigger are of interest for soft robotics and targeted therapeutic delivery. Here, the authors report on the development of DNA-crosslinked hydrogels which can expand upon the detection of different biomo
Externí odkaz:
https://doaj.org/article/3241bf86890d4f8b8b342683442b1442
Publikováno v:
ACS Materials Letters. 4:1807-1814
The programmable spatiotemporal activation of molecules could be used to create stimuli-responsive biomaterials capable of executing multistage sensing and computational processes. Here we develop a method for the activation of different DNA molecule
Autor:
Kuan-Lin Chen, Jackson O'Brien, Madeline Noble, Arvind Murugan, Samuel W. Schaffter, Rebecca Schulman
Publikováno v:
Nature Chemistry. 14:1224-1232
Engineered far-from-equilibrium synthetic chemical networks that pulse or switch states in response to environmental signals could precisely regulate the kinetics of chemical synthesis or self-assembly pathways. Currently, such networks must be exten