Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Rebecca, O'Connor"'
Autor:
Rebecca O’Connor, J.D.
Publikováno v:
F&S Reports, Vol 5, Iss 3, Pp 233- (2024)
Externí odkaz:
https://doaj.org/article/dad008e04f974f01b4861305e9ef15bc
Autor:
Joshua A. Lees, João M. Dias, Francis Rajamohan, Jean-Philippe Fortin, Rebecca O’Connor, Jimmy X. Kong, Emily A. G. Hughes, Ethan L. Fisher, Jamison B. Tuttle, Gabrielle Lovett, Bethany L. Kormos, Rayomand J. Unwalla, Lei Zhang, Anne-Marie Dechert Schmitt, Dahui Zhou, Michael Moran, Kimberly A. Stevens, Kimberly F. Fennell, Alison E. Varghese, Andrew Maxwell, Emmaline E. Cote, Yuan Zhang, Seungil Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract GPR61 is an orphan GPCR related to biogenic amine receptors. Its association with phenotypes relating to appetite makes it of interest as a druggable target to treat disorders of metabolism and body weight, such as obesity and cachexia. To d
Externí odkaz:
https://doaj.org/article/5d8246b6d9824727b8ad761786a5eac1
Autor:
Britton Boras, Rhys M. Jones, Brandon J. Anson, Dan Arenson, Lisa Aschenbrenner, Malina A. Bakowski, Nathan Beutler, Joseph Binder, Emily Chen, Heather Eng, Holly Hammond, Jennifer Hammond, Robert E. Haupt, Robert Hoffman, Eugene P. Kadar, Rob Kania, Emi Kimoto, Melanie G. Kirkpatrick, Lorraine Lanyon, Emma K. Lendy, Jonathan R. Lillis, James Logue, Suman A. Luthra, Chunlong Ma, Stephen W. Mason, Marisa E. McGrath, Stephen Noell, R. Scott Obach, Matthew N. O’ Brien, Rebecca O’Connor, Kevin Ogilvie, Dafydd Owen, Martin Pettersson, Matthew R. Reese, Thomas F. Rogers, Romel Rosales, Michelle I. Rossulek, Jean G. Sathish, Norimitsu Shirai, Claire Steppan, Martyn Ticehurst, Lawrence W. Updyke, Stuart Weston, Yuao Zhu, Kris M. White, Adolfo García-Sastre, Jun Wang, Arnab K. Chatterjee, Andrew D. Mesecar, Matthew B. Frieman, Annaliesa S. Anderson, Charlotte Allerton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The 3CL protease of SARS-CoV-2 is inhibited by PF-00835231 in vitro. Here, the authors show that the prodrug PF-07304814 has broad spectrum activity, inhibiting SARS-CoV and SARS-CoV-2 in mice and its ADME and safety profile support clinical developm
Externí odkaz:
https://doaj.org/article/7c0ac56767d64fb5af7714d7f3a62322
Autor:
Michelle R. Garnsey, Aaron C. Smith, Jana Polivkova, Autumn L. Arons, Guoyun Bai, Caroline Blakemore, Markus Boehm, Leanne M. Buzon, Sarah N. Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A. Farley, Kari R. Fonseca, Kristen K. Ford, Jeonifer Garren, Jimmy X. Kong, Martin R. M. Koos, Daniel W. Kung, Yajing Lian, Monica M. Li, Qifang Li, Luis A. Martinez-Alsina, Rebecca O’Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R. Reese, Tim Ryder, Lacey Samp, Kimberly A. Stevens, Daniel W. Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F. Sammons
Publikováno v:
Journal of Medicinal Chemistry. 66:3195-3211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba50d658838cab5c2164045c8015f51
https://doi.org/10.1021/acs.jmedchem.2c02012
https://doi.org/10.1021/acs.jmedchem.2c02012
Autor:
Joshua A. Lees, João M. Dias, Francis Rajamohan, Jean-Philippe Fortin, Rebecca O’Connor, Jimmy X. Kong, Emily Hughes, Ethan L. Fisher, Jamison B. Tuttle, Gabrielle Lovett, Bethany L. Kormos, Rayomand J. Unwalla, Lei Zhang, Anne-Marie Dechert Schmidt, Dahui Zhou, Kimberly A. Stevens, Kimberly F. Fennell, Alison E. Varghese, Andrew Maxwell, Emmaline E. Cote, Yuan Zhang, Seungil Han
GPR61 is a biogenic amine receptor-related orphan GPCR associated with phenotypes relating to appetite and thus, is of interest as a druggable target to treat disorders of metabolism and body weight, such as obesity and cachexia. To date, lack of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76acb6e0af1f71354ac4bc6320c62e67
https://doi.org/10.1101/2023.05.01.538732
https://doi.org/10.1101/2023.05.01.538732
Autor:
Wendy L. Magee, Ajit Narayanan, Rebecca O'Connor, Fiona Haughey, Erin Wegener, Bernice H.L. Chu, Mark Delargy, Dee Gray, Alika D. Seu, Richard J. Siegert, Rosanne J. Tyas, Kudret C. Yelden, Caroline Schnakers
Publikováno v:
Archives of Physical Medicine and Rehabilitation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae12e030d1a43aade584fc6ae7f53c64
https://doi.org/10.1016/j.apmr.2023.03.010
https://doi.org/10.1016/j.apmr.2023.03.010
Autor:
Kathryn M Porter, Stephanie A Kraft, Candace D Speight, Devan M Duenas, Nyiramugisha K Niyibizi, Andrea Mitchell, M Rebecca O’Connor, Charles Gregor, Kendra Liljenquist, Seema K Shah, Benjamin S Wilfond, Neal W Dickert
Publikováno v:
JAMIA Open. 6
Objective Research recruitment through patient portals (ie, patient-facing, web-based clinical interfaces) has the potential to be effective, efficient, and inclusive, but best practices remain undefined. We sought to better understand how patients v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3f5aa79f729bf4efc5d732a35f2d8a7
https://doi.org/10.1093/jamiaopen/ooad004
https://doi.org/10.1093/jamiaopen/ooad004
Publikováno v:
Clinical Simulation in Nursing. 49:58-65
Background To promote patient-centered care, nursing education must broadly address diversity, equity, and inclusion (DEI). Method Needs assessment data were collected from faculty and students via online surveys and focus groups. Results Students ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e072adbdd49f988fbda55488634bd3
https://doi.org/10.1016/j.ecns.2020.05.007
https://doi.org/10.1016/j.ecns.2020.05.007
Autor:
Nikola Sprigg, Rebecca O'Connor, Lisa Woodhouse, Kailash Krishnan, Timothy J England, Louise A Connell, Marion F Walker, Philip M Bath
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161359 (2016)
BACKGROUND:Granulocyte-colony stimulating factor (G-CSF) mobilises endogenous haematopoietic stem cells and enhances recovery in experimental stroke. Recovery may also be dependent on an enriched environment and physical activity. G-CSF may have the
Externí odkaz:
https://doaj.org/article/31d7ab8df92f4812b1ac42b4fd5981c7
Autor:
Molly R. Altman, Wendy E. Barrington, Ira Kantrowitz-Gordon, A. B. de Castro, Katie Malcolm, M. Rebecca O’Connor, Elba Moise, Milan Vidaković
Publikováno v:
Nurse Educator. 46:284-289
Background Case-based learning has historically focused on the individual patient; however, there is often little consideration within this teaching method of how social determinants of health, such as structural racism and its adverse health effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd64e22a49e6873d55aef9bef6423906
https://doi.org/10.1097/nne.0000000000000937
https://doi.org/10.1097/nne.0000000000000937