Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rebecca, Broome"'
Autor:
Rebecca Broome, Igor Chernukhin, Stacey Jamieson, Kamal Kishore, Evangelia K. Papachristou, Shi-Qing Mao, Carmen Gonzalez Tejedo, Areeb Mahtey, Vasiliki Theodorou, Arnoud J. Groen, Clive D’Santos, Shankar Balasubramanian, Anca Madalina Farcas, Rasmus Siersbæk, Jason S. Carroll
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108776- (2021)
Summary: Estrogen receptor-α (ER) drives tumor development in ER-positive (ER+) breast cancer. The transcription factor GATA3 has been closely linked to ER function, but its precise role in this setting remains unclear. Quantitative proteomics was u
Externí odkaz:
https://doaj.org/article/2f967e69b4e24dc196b740e2f994b931
Autor:
Timo Heinrich, Carl Peterson, Richard Schneider, Sakshi Garg, Daniel Schwarz, Jakub Gunera, Anita Seshire, Lisa Kötzner, Sarah Schlesiger, Djordje Musil, Heike Schilke, Benjamin Doerfel, Patrizia Diehl, Pia Böpple, Ana R. Lemos, Pedro M. F. Sousa, Filipe Freire, Tiago M. Bandeiras, Emma Carswell, Nicholas Pearson, Sameer Sirohi, Mollie Hooker, Elisabeth Trivier, Rebecca Broome, Alexander Balsiger, Abigail Crowden, Christian Dillon, Dirk Wienke
Publikováno v:
Journal of Medicinal Chemistry. 65:9206-9229
Autor:
Carmen Gonzalez Tejedo, Kamal Kishore, Areeb Mahtey, Shi-Qing Mao, Clive D'Santos, Stacey Jamieson, Arnoud J. Groen, Rebecca Broome, Shankar Balasubramanian, Rasmus Siersbæk, Igor Chernukhin, Evangelia K. Papachristou, Vasiliki Theodorou, Anca M. Farcas, Jason S. Carroll
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108776-(2021)
Broome, R, Chernukhin, I, Jamieson, S, Kishore, K, Papachristou, E K, Mao, S-Q, Tejedo, C G, Mahtey, A, Theodorou, V, Groen, A J, D'Santos, C, Balasubramanian, S, Farcas, A M, Siersbaek, R & Carroll, J S 2021, ' TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions ', Cell Reports, vol. 34, no. 8, 108776 . https://doi.org/10.1016/j.celrep.2021.108776
Cell Reports
Broome, R, Chernukhin, I, Jamieson, S, Kishore, K, Papachristou, E K, Mao, S-Q, Tejedo, C G, Mahtey, A, Theodorou, V, Groen, A J, D'Santos, C, Balasubramanian, S, Farcas, A M, Siersbaek, R & Carroll, J S 2021, ' TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions ', Cell Reports, vol. 34, no. 8, 108776 . https://doi.org/10.1016/j.celrep.2021.108776
Cell Reports
Summary Estrogen receptor-α (ER) drives tumor development in ER-positive (ER+) breast cancer. The transcription factor GATA3 has been closely linked to ER function, but its precise role in this setting remains unclear. Quantitative proteomics was us
Autor:
Jason S. Carroll, Stacey E. P. Joosten, Rasmus Siersbæk, Andrew R. Green, Wilbert Zwart, Danya Cheeseman, Igor Chernukhin, Emad A. Rakha, Rebecca Broome, Evangelia K. Papachristou, Sankari Nagarajan, Soleilmane Omarjee, Ruben Alvarez-Fernandez, Valentina Scabia, Julia P. G. Jones, Clive D'Santos, Kamal Kishore, Simon J Johnston, Sanjeev Kumar, Silvia Glont, Cathrin Brisken, Alasdair Russell, Sarah J. Aitken
Publikováno v:
Cancer Cell, 38(3), 412-423.e9. Cell Press
Cancer Cell
Nagarajan, S 2020, ' IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis ', Cancer Cell, vol. 38, no. 3, pp. 412-423.e9 . https://doi.org/10.1016/j.ccell.2020.06.007
Cancer Cell
Nagarajan, S 2020, ' IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis ', Cancer Cell, vol. 38, no. 3, pp. 412-423.e9 . https://doi.org/10.1016/j.ccell.2020.06.007
The cytokine interleukin-6 (IL6) and its downstream effector STAT3 constitute a key oncogenic pathway, which has been thought to be functionally connected to estrogen receptor α (ER) in breast cancer. We demonstrate that IL6/STAT3 signaling drives m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c6a2f9f6f6c6701d97d8fee070656e
https://research.tue.nl/nl/publications/9a7ad21c-f148-4b84-8a85-7fca9a6c5d2c
https://research.tue.nl/nl/publications/9a7ad21c-f148-4b84-8a85-7fca9a6c5d2c
Autor:
Igor Chernukhin, Sanjeev Srinivas Kumar, Wilbert Zwart, Rasmus Siersbæk, Ruben Alvarez, Emad A. Rakha, Rebecca Broome, Andrew R. Green, Sankari Nagarajan, Soleilmane Omarjee, Clive D'Santos, Stacey E. P. Joosten, Cathrin Brisken, Alasdair Russell, Valentina Scabia, Eva Papachristou, Silvia Glont, Sarah J. Aitken, Kamal Kishore, Jason S. Carroll
Publikováno v:
Oncology Abstracts.
Autor:
Peter Baillie-Johnson, David A. Turner, Fernando Faunes, Penelope Hayward, Pau Rué, Rebecca Broome, Alfonso Martinez Arias
Publikováno v:
Development (Cambridge, England)
The development of the central nervous system is known to result from two sequential events. First, an inductive event of the mesoderm on the overlying ectoderm that generates a neural plate that, after rolling into a neural tube, acts as the main so