Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebeca Martín-Jiménez"'
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTAccumulation of Lewy bodies in dopaminergic neurons is associated to Parkinson disease (PD). The main component of Lewy bodies appears to be aggregates of alpha-synuclein (α-syn). Several mutations of the gene encoding this protein promote i
Externí odkaz:
https://doaj.org/article/96e37761fef2496f8dfac422d08f0b6f
Autor:
Olivier Lurette, Rebeca Martín-Jiménez, Mehtab Khan, Razan Sheta, Stéphanie Jean, Mia Schofield, Maxime Teixeira, Raquel Rodriguez-Aller, Isabelle Perron, Abid Oueslati, Etienne Hebert-Chatelain
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Accumulation of α-synuclein aggregates in the substantia nigra pars compacta is central in the pathophysiology of Parkinson’s disease, leading to the degeneration of dopaminergic neurons and the manifestation of motor symptoms. Although s
Externí odkaz:
https://doaj.org/article/c078e0cade00424082d97a16652c017e
Autor:
Olivier Lurette, Hala Guedouari, Jordan L. Morris, Rebeca Martín-Jiménez, Julie-Pier Robichaud, Geneviève Hamel-Côté, Mehtab Khan, Nicholas Dauphinee, Nicolas Pichaud, Julien Prudent, Etienne Hebert-Chatelain
The architecture of mitochondria adapts to physiological contexts: while mitochondrial fragmentation is usually associated to quality control and cell death, mitochondrial elongation often enhances cell survival during stress. Understanding how these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ffa67547c42aa0ee1321ec7851f160
https://www.repository.cam.ac.uk/handle/1810/338522
https://www.repository.cam.ac.uk/handle/1810/338522
Publikováno v:
DNA and Cell Biology. 39:1421-1430
Mitochondria are the only organelles that contain their own genetic material (mtDNA). Mitochondria are involved in several key physiological functions, including ATP production, Ca2+ homeostasis, and metabolism of neurotransmitters. Since these organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709e33d94cda76cb4fdda13f5e7ea5a8
https://doi.org/10.1089/dna.2020.5398
https://doi.org/10.1089/dna.2020.5398
Autor:
Marie-Ange Djeungoue-Petga, Olivier Lurette, Astrid Cannich, Stéphanie Jean, Rebeca Martín-Jiménez, Geneviève Hamel-Côté, Etienne Hebert-Chatelain, Marine Bou, Patrick Roy
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-15 (2019)
Cell Death and Disease, Vol 10, Iss 12, Pp 1-15 (2019)
High levels and activity of Src kinase are common among breast cancer subtypes, and several inhibitors of the kinase are currently tested in clinical trials. Alterations in mitochondrial activity is also observed among the different types of breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb21672a122cfc9fce083ea4a3f240
http://europepmc.org/articles/PMC6901437
http://europepmc.org/articles/PMC6901437
Autor:
Stefania Cocco, Ramona Lupi, Giusy Amadoro, Michelangelo Campanella, Ivana Matic, Giuseppe Pignataro, Andrey Y. Abramov, Fulvio Florenzano, Caterina Ferraina, James Crosby, Rebeca Martín-Jiménez, Claire Russell, Lucio Annunziato
Publikováno v:
Pharmacological Research
The mitochondrial ATPase Inhibitory Factor 1 (hereafter referred to as IF1) blocks the reversal of the F1Fo-ATPsynthase to prevent detrimental consumption of cellular ATP and associated demise. Herein, we infer further its molecular physiology by ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04f4ff7cc47c66db4f31ddf70a9cde4
https://doi.org/10.1016/j.phrs.2015.10.010
https://doi.org/10.1016/j.phrs.2015.10.010
Autor:
Michelangelo Campanella, Holly Beatrice Reichel, Rebeca Martín-Jiménez, Daniela Strobbe, Emma Allen, Danilo Faccenda, Laura Arcos, Claire Russell, Caterina Ferraina
Publikováno v:
Cell Death and Disease, Vol 9, Iss 6, Pp 1-13 (2018)
CELL DEATH & DISEASE
Cell Death & Disease
CELL DEATH & DISEASE
Cell Death & Disease
In vertebrates, mitochondria are tightly preserved energy producing organelles, which sustain nervous system development and function. The understanding of proteins that regulate their homoeostasis in complex animals is therefore critical and doing s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cd0a5d505bd70941456a265a438a0a
http://hdl.handle.net/2108/265083
http://hdl.handle.net/2108/265083
Clinical and cellular consequences of the mutation m.12300G>A in the mitochondrial tRNALeu(CUN) gene
Autor:
Yolanda Campos, María Teresa García-Silva, Ana Cabello, Rebeca Martín-Jiménez, Joaquín Arenas, Elena Martín-Hernández
Publikováno v:
Mitochondrion. 12:288-293
We report, for the first time, a patient with an overlap MERRF–NARP syndrome who carries the mutation m.12300G>A in the mitochondrial tRNA Leu(CUN) gene. The mutation was heteroplamic and more abundant in her muscle and fibroblast than in blood fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d868c544a83135124a8349c685d45c7
https://doi.org/10.1016/j.mito.2011.10.004
https://doi.org/10.1016/j.mito.2011.10.004
Publikováno v:
Current Neurology and Neuroscience Reports
In modern biomedicine, the increasing need to develop experimental models to further our understanding of disease conditions and delineate innovative treatments has found in the zebrafish (Danio rerio) an experimental model, and indeed a valuable ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704186e8923658da8ac6f2331f9909ce
https://pubmed.ncbi.nlm.nih.gov/25903297
https://pubmed.ncbi.nlm.nih.gov/25903297
Autor:
Lurette, Olivier, Martín-Jiménez, Rebeca, Khan, Mehtab, Sheta, Razan, Jean, Stéphanie, Schofield, Mia, Teixeira, Maxime, Rodriguez-Aller, Raquel, Perron, Isabelle, Oueslati, Abid, Hebert-Chatelain, Etienne
Publikováno v:
Cell Death & Disease; Nov2023, Vol. 14 Issue 11, p1-14, 14p