Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Reba K. Wright"'
Publikováno v:
Journal of Clinical Oncology. 5:804-810
We determined the risk of impaired excretion of methotrexate (MTX) in children with osteosarcoma, who also were receiving cisplatin, by analyzing urinary markers of renal tubular damage, as well as serum creatinine measured before each dose of MTX. M
Autor:
William C. Duckworth, Keith R. Runyan, Solomon S. Solomon, Reba K. Wright, Philippe A. Halban
Publikováno v:
Endocrinology, Vol. 108, No 4 (1981) pp. 1142-1147
The mechanism by which the liver degrades insulin has not yet been completely clarified. In intact, non-"leaky" cells the primary process seems to be mediated by initial receptor binding. We now demonstrate that isolated rat hepatocytes in primary cu
Publikováno v:
Clinical Chemistry. 32:2052-2055
We automated two procedures for determination of urinary N-acetyl-beta-D-glucosaminidase (NAG; EC 3.2.1.30) concentrations and evaluated their reliability for detecting drug-induced tubular damage in children receiving cisplatin, methotrexate, or ifo
Publikováno v:
Advances in Enzyme Regulation. 12:205-216
Adenyl cyclase was demonstrated in slices of human skin and in the 650 × g pellet of skin homogenates. The slices were obtained with a keratome, and consisted mostly of epidermis. After the incubation of the slices with [ 3 H] adenine, 3 H was found
Publikováno v:
Cancer Chemotherapy and Pharmacology. 18:69-73
We assessed the acute and chronic effect of multiple courses of cisplatin therapy on renal tubules by monitoring the urinary excretion of alanine aminopeptidase, N-acetyl-beta-D-glucosaminidase, and total protein. Urine specimens were obtained before
Publikováno v:
Clinical Chemistry. 32:548-551
We evaluated an enzymatic procedure for the automated determination of serum and urinary creatinine. The procedure was sensitive and precise for serum creatinine concentrations as low as 3 mg/L, and the standard curve was linear to 200 mg/L. Measurem
Publikováno v:
Journal of Investigative Dermatology. (1):109-113
After the incubation of slices of human skin with adenine-2,8- 3 H in the presence of theophylline, 3 H was found in cAMP, indicating the presence of adenyl cyclase in human skin. This activity was stimulated by epinephrine and NaF. Specimens of psor
Autor:
Elizabeth Milikin, Francis Binkley, Reba K. Wright, Ina Jane Wundram, Neva King, C. H. O'Neal
Publikováno v:
Science. 162:1009-1011
Particulates containing a large part of the alkaline phosphatase activity of renal tissue were separated from homogenates and from ribosomal preparations by zonal centrifugation. The particles had a high content of phospholipid and cholesterol that w
Publikováno v:
Diabetes. 31(12)
We have used two methods for the preparation of a highly homogeneous insulin with high specific activity. After iodination with chloramine T, the labeled peptides were retained on a disposable Sep Pak cartridge and subsequently eluted. The eluted lab
Autor:
Donald K. Baker, Jerry L. Shenep, Reba K. Wright, Mary J. Viar, Marshall P. Goren, David K. Kalwinsky
Publikováno v:
The Pediatric infectious disease journal. 7(10)
We prospectively studied the effect of amphotericin B therapy on aminoglycoside clearance in 20 consecutive children during the remission-induction phase of chemotherapy for acute myelocytic leukemia. Increases (greater than 50%) in the half-life for