Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Reba Condiotti"'
Autor:
Benjamin Assouline, Rachel Kahn, Lutfi Hodali, Reba Condiotti, Yarden Engel, Ela Elyada, Tzlil Mordechai-Heyn, Jason R. Pitarresi, Dikla Atias, Eliana Steinberg, Tirza Bidany-Mizrahi, Esther Forkosh, Lior H. Katz, Ofra Benny, Talia Golan, Matan Hofree, Sheila A. Stewart, Karine A. Atlan, Gideon Zamir, Ben Z. Stanger, Michael Berger, Ittai Ben-Porath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Senescent cells within tumors and their stroma exert complex pro- and anti-tumorigenic functions. However, the identities and traits of these cells, and the potential for improving cancer therapy through their targeting, remain poorly charac
Externí odkaz:
https://doaj.org/article/3aed130938ea4e87851508070eec5837
Autor:
Roy Z. Granit, Hadas Masury, Reba Condiotti, Yaakov Fixler, Yael Gabai, Tzofia Glikman, Simona Dalin, Eitan Winter, Yuval Nevo, Einat Carmon, Tamar Sella, Amir Sonnenblick, Tamar Peretz, Ulrich Lehmann, Keren Paz, Federica Piccioni, Aviv Regev, David E. Root, Ittai Ben-Porath
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3237-3250 (2018)
Summary: Differentiation events contribute to phenotypic cellular heterogeneity within tumors and influence disease progression and response to therapy. Here, we dissect mechanisms controlling intratumoral heterogeneity within triple-negative basal-l
Externí odkaz:
https://doaj.org/article/17fd09a8613d4560b76a4fa0d578df12
Autor:
Reut Yosef, Noam Pilpel, Ronit Tokarsky-Amiel, Anat Biran, Yossi Ovadya, Snir Cohen, Ezra Vadai, Liat Dassa, Elisheva Shahar, Reba Condiotti, Ittai Ben-Porath, Valery Krizhanovsky
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The accumulation of senescent cells within tissues plays a role in numerous age-related pathologies. Yosef and Pilpel et al. demonstrate that the resistance of these cells to apoptosis is driven by upregulation of survival proteins, whose pharmacolog
Externí odkaz:
https://doaj.org/article/560479e5b34747fb9d70b2a5aea7e0c2
Autor:
Gideon Hen, Sara Yosefi, Dmitry Shinder, Adi Or, Sivan Mygdal, Reba Condiotti, Eithan Galun, Amir Bor, Dalit Sela-Donenfeld, Miriam Friedman-Einat
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138629 (2015)
Externí odkaz:
https://doaj.org/article/3563c8f9eb7640d5ac2071f63bf16457
Autor:
Gideon Hen, Sara Yosefi, Dmitry Shinder, Adi Or, Sivan Mygdal, Reba Condiotti, Eithan Galun, Amir Bor, Dalit Sela-Donenfeld, Miriam Friedman-Einat
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36531 (2012)
The lack of affordable techniques for gene transfer in birds has inhibited the advancement of molecular studies in avian species. Here we demonstrate a new approach for introducing genes into chicken somatic tissues by administration of a lentiviral
Externí odkaz:
https://doaj.org/article/437e5b61e79640ba94be725054b41893
Autor:
Gideon Hen, Sara Yosefi, Dmitry Shinder, Adi Or, Sivan Mygdal, Reba Condiotti, Eithan Galun, Amir Bor, Dalit Sela-Donenfeld, Miriam Friedman-Einat
Publikováno v:
PLoS ONE, Vol 7, Iss 7 (2012)
Externí odkaz:
https://doaj.org/article/9fa34308612f40b0a518577a2c1f0316
Autor:
Aviv Regev, Tzofia Glikman, Ittai Ben-Porath, Yuval Nevo, Yael Gabai, Reba Condiotti, Roy Z. Granit, Federica Piccioni, Ulrich Lehmann, Einat Carmon, David E. Root, Keren Paz, Amir Sonnenblick, Tamar Sella, Tamar Peretz, Eitan Winter, Hadas Masury, Simona Dalin, Yaakov Fixler
Publikováno v:
Elsevier
Cell Reports, Vol 24, Iss 12, Pp 3237-3250 (2018)
Cell Reports, Vol 24, Iss 12, Pp 3237-3250 (2018)
Summary: Differentiation events contribute to phenotypic cellular heterogeneity within tumors and influence disease progression and response to therapy. Here, we dissect mechanisms controlling intratumoral heterogeneity within triple-negative basal-l
Autor:
Amit Zamir, Ittai Ben-Porath, Sharona Tornovsky-Babeay, Yael Gabai, Reba Condiotti, Shira Anzi, Yaakov Fixler, A. M. James Shapiro, Agnes Klochendler, Elad Horwitz, Aharon Helman, Narmen Azazmeh, Alvin C. Powers, Chunhua Dai, Mark A. Magnuson, Roy Z. Granit, Benjamin Glaser, Avital Swisa, Dorin Shreibman, Yuval Dor, Yuval Nevo
Publikováno v:
Nature Medicine. 22:412-420
Cellular senescence is thought to contribute to age-associated deterioration of tissue physiology. The senescence effector p16(Ink4a) is expressed in pancreatic beta cells during aging and limits their proliferative potential; however, its effects on
Autor:
Merav Hecht, Hagit Masika, Yehudit Bergman, Yosef Buganim, Kirill Makedonski, Howard Cedar, Reba Condiotti, Tal Burstyn-Cohen, Marganit Farago
Publikováno v:
Nature structuralmolecular biology. 24(12)
Many regions of the genome replicate asynchronously and are expressed monoallelically. It is thought that asynchronous replication may be involved in choosing one allele over the other, but little is known about how these patterns are established dur
Autor:
Elisheva Shahar, Ezra Vadai, Reba Condiotti, Reut Yosef, Valery Krizhanovsky, Anat Biran, Ronit Tokarsky-Amiel, Liat Dassa, Snir Cohen, Yossi Ovadya, Noam Pilpel, Ittai Ben-Porath
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Senescent cells, formed in response to physiological and oncogenic stresses, facilitate protection from tumourigenesis and aid in tissue repair. However, accumulation of such cells in tissues contributes to age-related pathologies. Resistance of sene