Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Reagan M Mogire"'
Autor:
Reagan M Mogire, MSc, Agnes Mutua, BSc, Wandia Kimita, MSc, Alice Kamau, MSc, Philip Bejon, PhD, John M Pettifor, MBBCh, Adebowale Adeyemo, MD, Thomas N Williams, FMedSci, Sarah H Atkinson, PhD
Publikováno v:
The Lancet Global Health, Vol 8, Iss 1, Pp e134-e142 (2020)
Summary: Background: Vitamin D deficiency is associated with non-communicable and infectious diseases, but the vitamin D status of African populations is not well characterised. We aimed to estimate the prevalence of vitamin D deficiency in children
Externí odkaz:
https://doaj.org/article/3e4e8993f67d4108b7b1aa71a99a4804
Autor:
Reagan M Mogire, Hoseah M Akala, Rosaline W Macharia, Dennis W Juma, Agnes C Cheruiyot, Ben Andagalu, Mathew L Brown, Hany A El-Shemy, Steven G Nyanjom
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186364 (2017)
Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible for 90% of all the cases. Recent reports on artemisinin resistance in Southeast Asia warrant urgent discovery of novel drugs for the treatment of malari
Externí odkaz:
https://doaj.org/article/bc5a78fc4ecc46e3a76e2e60ee241e49
Autor:
Reagan M. Mogire, Silviane A. Miruka, Dennis W. Juma, Case W. McNamara, Ben Andagalu, Jeremy N. Burrows, Elodie Chenu, James Duffy, Bernhards R. Ogutu, Hoseah M. Akala
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Drug discovery is an intricate and costly process. Repurposing existing drugs and active compounds offers a viable pathway to develop new therapies for various diseases. By leveraging publicly available biomedical information, it is possible
Externí odkaz:
https://doaj.org/article/9abd7be432b44ac9ad401606323a2e80
Autor:
Douglas O. Ochora, Reagan M. Mogire, Rael J. Masai, Redemptah A. Yeda, Edwin W. Mwakio, Joseph G. Amwoma, Dancan M. Wakoli, Abiy Yenesew, Hoseah M. Akala
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18863- (2023)
High malaria mortality coupled with increased emergence of resistant multi-drug resistant strains of Plasmodium parasite, warrants the development of new and effective antimalarial drugs. However, drug design and discovery are costly and time-consumi
Externí odkaz:
https://doaj.org/article/a258085fcfe7472da69c1f3c36cc1485
Autor:
Reagan M. Mogire, Alireza Morovat, John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Manjinder S. Sandhu, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Children living in sub-Saharan Africa have a high burden of rickets and infectious diseases, conditions that are linked to vitamin D deficiency. However, data on the vitamin D status of young African children and its environmental
Externí odkaz:
https://doaj.org/article/af36fc5b4df647808f587d75066738fb
Autor:
Kelvin M. Abuga, John Muthii Muriuki, Sophie M. Uyoga, Kennedy Mwai, Johnstone Makale, Reagan M. Mogire, Alex W. Macharia, Shebe Mohammed, Esther Muthumbi, Salim Mwarumba, Neema Mturi, Philip Bejon, J. Anthony G. Scott, Manfred Nairz, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
Haematologica, Vol 107, Iss 7 (2021)
Malaria and invasive non-typhoidal Salmonella (NTS) are life-threatening infections that often co-exist in African children. The iron-regulatory hormone hepcidin is highly upregulated during malaria and controls the availability of iron, a critical n
Externí odkaz:
https://doaj.org/article/5f273c88ed874845bcbc4abc14da9594
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards R. Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1371 (2022)
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of act
Externí odkaz:
https://doaj.org/article/51f533a3d8a647a8b2b71052ec3441fa
Autor:
Shebe Mohammed, Kennedy Mwai, Johnstone Makale, Neema Mturi, Thomas N. Williams, Alex Macharia, Sarah H. Atkinson, Esther Muthumbi, Salim Mwarumba, John Muthii Muriuki, Reagan M. Mogire, Philip Bejon, Manfred Nairz, J. Anthony G. Scott, Kelvin M. Abuga, Sophie Uyoga
Publikováno v:
Haematologica. 107:1589-1598
Malaria and invasive non-typhoidal Salmonella (NTS) are life-threatening infections that often co-exist in African children. The iron-regulatory hormone hepcidin is highly upregulated during malaria and controls the availability of iron, a critical n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ee1cbd8a9c48a4d3846c3877940e58
https://doi.org/10.3324/haematol.2021.279316
https://doi.org/10.3324/haematol.2021.279316
Autor:
Reagan M. Mogire, John Muthii Muriuki, Alireza Morovat, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
Nutrients; Volume 14; Issue 7; Pages: 1372
NUTRIENTS
NUTRIENTS
Vitamin D regulates the master iron hormone hepcidin, and iron in turn alters vitamin D metabolism. Although vitamin D and iron deficiency are highly prevalent globally, little is known about their interactions in Africa. To evaluate associations bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d2f577aab8b665eb00829b8f5295d1
https://pubmed.ncbi.nlm.nih.gov/35405984
https://pubmed.ncbi.nlm.nih.gov/35405984
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Raman Mathur, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984194993f8cdc9e370e3c46efc0504c
https://doi.org/10.2139/ssrn.4002022
https://doi.org/10.2139/ssrn.4002022