Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Read R. Taintor"'
Publikováno v:
Methods. 7:78-83
In this article we discuss methodology for quantitation of nitrite and nitrate, end products of the biological synthesis of nitric oxide from L-arginine. Both nitrite and nitrate can be measured, with accuracy to the low micromolar range, using bacte
Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction
Publikováno v:
Methods in Enzymology ISBN: 9780121821692
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a737ced5f0131e72f444b887ac85ec92
https://doi.org/10.1016/s0076-6879(96)68016-1
https://doi.org/10.1016/s0076-6879(96)68016-1
Autor:
C. Kablitz, R. L. Menlove, Read R. Taintor, M. P. McMurry, R. L. Baranowski, Zdenek Vavrin, James P. Kushner, John B. Hibbs, John H. Ward, Christof Westenfelder
An interferon-gamma, tumor necrosis factor, and interleukin-1-inducible, high-output pathway synthesizing nitric oxide (NO) from L-arginine was recently identified in rodents. High-dose interleukin-2 (IL-2) therapy is known to induce the same cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdb15f8586f42386c5e6ecc3421ec52
https://europepmc.org/articles/PMC442932/
https://europepmc.org/articles/PMC442932/
Autor:
Charles J. Parker, Read R. Taintor, Ina J. Amber, Zdenek Vavrin, Barbara B. Johnson, John B. Hibbs
Publikováno v:
Journal of leukocyte biology. 49(6)
Conditioned medium (CM) from cultures of cytotoxic activated macrophages causes inhibition of mitochondrial respiration, DNA synthesis, and aconitase activity in murine EMT-6 mammary adenocarcinoma cells by an l-arginine dependent effector mechanism.
Publikováno v:
Science. 235:473-476
Previous studies have shown that cytotoxic activated macrophages cause inhibition of DNA synthesis, of mitochondrial respiration, and of aconitase activity in tumor target cells. An L-arginine-dependent biochemical pathway synthesizing L-citrulline a
SHORT COMMUNICATION: Cytokines Induce an L-Arginine-Dependent Effector System in Nonmacrophage Cells
Publikováno v:
Journal of Leukocyte Biology. 44:58-65
Treatment of EMT-6 mammary adenocarcinoma cells with gamma interferon (rMuIFNγ) plus tumor necrosis factor (rMuTNFα) and/or interleukin-1 (rHuIL-1α) causes release of iron-55 label, inhibition of DNA replication, and inhibition of aconitase activi
Publikováno v:
Journal of leukocyte biology. 43(2)
Culture medium conditioned by incubation with murine cytotoxic activated macrophages causes release of iron-55 label from viable murine EMT-6 tumor cells as well as inhibition of DNA replication and aconitase activity. These metabolic changes occur i
Publikováno v:
Science (New York, N.Y.). 197(4300)
Tumor killing by activated macrophages is not a highly determined biologic event, but a relative capability influenced by the local environment. An intrinsic macrophage cytotoxic effector system is modulated by serum and other environmental factors t
Publikováno v:
The Journal of clinical investigation. 65(2)
Cytotoxic activated macrophages (CM) inhibited the growth of neoplastic L1210 cells in vitro but L1210 cell death was minimal to nonexistent. L1210 cells injured by CM were separated from macrophages and studied in an isolated system. CM-injured L121