The adjuvant BcfA activates antigen presenting cells through TLR4 and supports T FH and T H 1 while attenuating T H 2 gene programming.

Autor: Shamseldin MM; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Departments of Microbiology, The Ohio State University, Columbus, OH, United States.; Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University-Ain Helwan, Helwan, Egypt., Read KA; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Hall JM; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Tuazon JA; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Brown JM; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Guo M; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Gupta YA; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Deora R; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Departments of Microbiology, The Ohio State University, Columbus, OH, United States., Oestreich KJ; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States., Dubey P; Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States.; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Aug 29; Vol. 15, pp. 1439418. Date of Electronic Publication: 2024 Aug 29 (Print Publication: 2024).

Revising VOC emissions speciation improves the simulation of global background ethane and propane.

Autor: Rowlinson MJ; National Centre for Atmospheric Science, University of York, York, YO10 5DD, UK.; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Evans MJ; National Centre for Atmospheric Science, University of York, York, YO10 5DD, UK.; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Carpenter LJ; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Read KA; National Centre for Atmospheric Science, University of York, York, YO10 5DD, UK.; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Punjabi S; National Centre for Atmospheric Science, University of York, York, YO10 5DD, UK.; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Adedeji A; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Fakes L; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Lewis A; National Centre for Atmospheric Science, University of York, York, YO10 5DD, UK.; Wolfson Atmospheric Chemistry Laboratories, Department of Chemistry, University of York, York, YO10 5DD, UK., Richmond B; Ricardo, Fermi Avenue, Harwell, Oxon, OX11 0QR, UK., Passant N; Ricardo, Fermi Avenue, Harwell, Oxon, OX11 0QR, UK., Murrells T; Ricardo, Fermi Avenue, Harwell, Oxon, OX11 0QR, UK., Henderson B; United States Environmental Protection Agency, Research Triangle Park, Durham, North Carolina 27709, USA., Bates KH; NOAA Chemical Sciences Laboratory, Boulder, CO, 80305, USA.; Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, CO, 80305, USA., Helmig D; Boulder A.I.R. LLC, Boulder, CO 80305, USA.

Publikováno v: Atmospheric chemistry and physics [Atmos Chem Phys] 2024 Jul 24; Vol. 24 (14), pp. 8317-8342.

PRMT5 Promotes T follicular helper Cell Differentiation and Germinal Center Responses during Influenza Virus Infection.

Autor: Read KA; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH., Amici SA; Division of Medical Laboratory Science, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH., Farsi S; Division of Medical Laboratory Science, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH., Cutcliffe M; Department of Internal Medicine, Division of Rheumatology-Immunology, The Ohio State University, Columbus, OH., Lee B; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH.; Medical Scientist Training Program, The Ohio State University College of Medicine, Columbus, OH., Lio CJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Pelotonia Institute for Immuno-Oncology; The Ohio State Comprehensive Cancer Center, Columbus, OH., Wu HJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Department of Internal Medicine, Division of Rheumatology-Immunology, The Ohio State University, Columbus, OH.; Pelotonia Institute for Immuno-Oncology; The Ohio State Comprehensive Cancer Center, Columbus, OH., Guerau-de-Arellano M; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Department of Internal Medicine, Division of Rheumatology-Immunology, The Ohio State University, Columbus, OH.; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH., Oestreich KJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Pelotonia Institute for Immuno-Oncology; The Ohio State Comprehensive Cancer Center, Columbus, OH.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 May 01; Vol. 212 (9), pp. 1442-1449.

TCDD and CH223191 Alter T Cell Balance but Fail to Induce Anti-Inflammatory Response in Adult Lupus Mice.

Autor: Gutierrez F; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Murphy QM; Department of Mathematics, Virginia Polytechnic Institute and State University, Blacksburg, VA., Swartwout BK; Translational Biology Medicine and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, VA., Read KA; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Edwards MR; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Abdelhamid L; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Cabana-Puig X; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Testerman JC; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Xu T; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Lu R; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Amin P; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Cecere TE; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA., Reilly CM; Department of Biomedical Sciences, Edward Via College of Osteopathic Medicine, Blacksburg, VA., Oestreich KJ; Department of Microbial Infection and Immunity, Ohio State University College of Medicine, Columbus, OH., Ciupe SM; Department of Mathematics, Virginia Polytechnic Institute and State University, Blacksburg, VA., Luo XM; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA.

Publikováno v: ImmunoHorizons [Immunohorizons] 2024 Feb 01; Vol. 8 (2), pp. 172-181.

Prime-Pull Immunization of Mice with a BcfA-Adjuvanted Vaccine Elicits Sustained Mucosal Immunity That Prevents SARS-CoV-2 Infection and Pathology.

Autor: Shamseldin MM; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Department of Microbiology, The Ohio State University, Columbus, OH.; Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University-Ain Helwan, Helwan, Egypt., Kenney A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Zani A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Evans JP; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH.; Center for Retrovirus Research, The Ohio State University, Columbus, OH., Zeng C; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH.; Center for Retrovirus Research, The Ohio State University, Columbus, OH., Read KA; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Hall JM; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Chaiwatpongsakorn S; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH., Mahesh KC; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH., Lu M; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH., Eltobgy M; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Denz P; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Deora R; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Department of Microbiology, The Ohio State University, Columbus, OH., Li J; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH., Peeples ME; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH.; Department of Pediatrics, The Ohio State University, Columbus, OH., Oestreich KJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Liu SL; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.; Department of Microbiology, The Ohio State University, Columbus, OH.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH.; Center for Retrovirus Research, The Ohio State University, Columbus, OH., Corps KN; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH., Yount JS; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Dubey P; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 May 01; Vol. 210 (9), pp. 1257-1271.