Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Reactome"'
Autor:
Remya James, Koushik Narayan Subramanyam, Febby Payva, Amrisa Pavithra E, Vineeth Kumar TV, Venketesh Sivaramakrishnan, Santhy KS
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Angiogenesis-osteogenesis coupling is critical for proper functioning and maintaining the health of bones. Any disruption in this coupling, associated with aging and disease, might lead to loss of bone mass. Osteoporosis (OP) is a debilitati
Externí odkaz:
https://doaj.org/article/7a61be558d2d46799edcbb0f90a9dd60
Autor:
Faiq, Muneeb A. a, b, c, d, e, f, ⁎⁎, Singh, Himanshu N. g, h, i, Ali, Mashooq b, Dada, Rima c, Chan, Kevin C. d, e, f, Dada, Tanuj a, ⁎, Saluja, Daman b, ⁎
Publikováno v:
In Vision Research February 2025 227
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Introduction Cross‐talk among biological pathways is essential for normal biological function and plays a significant role in cancer progression. Through integrated network analysis, this study explores the significance of pathway cross‐
Externí odkaz:
https://doaj.org/article/3c59ca9c6e4f4307b89eef9b494d92bc
Publikováno v:
Journal of Integrative Bioinformatics, Vol 20, Iss 3, Pp 524-31 (2023)
Many important aspects of biological knowledge at the molecular level can be represented by pathways. Through their analysis, we gain mechanistic insights and interpret lists of interesting genes from experiments (usually omics and functional genomic
Externí odkaz:
https://doaj.org/article/772230f017814a17ac25f624ec5b262c
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionMajor depressive disorder (MDD) is partially inheritable while its mechanism is still uncertain.MethodsThis cross-sectional study focused on gene pathways as a whole rather than polymorphisms of single genes. Deep sequencing and gene enri
Externí odkaz:
https://doaj.org/article/2c45910544234e4cb7e319b86138a15e
Publikováno v:
International Journal of Pharmaceutics: X, Vol 6, Iss , Pp 100215- (2023)
Metformin (MET), an oral antidiabetic drug, was reported to possess promising anticancer effects. We hypothesized that MET encapsulation in unique nanospanlastics would enhance its anticancer potential against HEP-2 cells. Our results showed the succ
Externí odkaz:
https://doaj.org/article/58f83445ab044d329374c262014e28e4
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1639-1650 (2023)
The immense structural diversity of products and intermediates of plant specialized metabolism (specialized metabolites) makes them rich sources of therapeutic medicine, nutrients, and other useful materials. With the rapid accumulation of reactome d
Externí odkaz:
https://doaj.org/article/8c79eec6ddd5494397a83b78b36666cb
Akademický článek
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Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionAndrogenetic alopecia (AGA) is a common progressive scalp hair loss disorder that leads to baldness. This study aimed to identify core genes and pathways involved in premature AGA through an in-silico approach.MethodsGene expression data
Externí odkaz:
https://doaj.org/article/377a99ca9153481991155c5d07782179
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Immune checkpoint inhibitors (ICIs) and Janus kinase inhibitors (JAKis) have raised concerns over serious unexpected cardiovascular adverse events. The widespread pleiotropy in genome-wide association studies offers an opportunity to identify cardiov
Externí odkaz:
https://doaj.org/article/49270518e05e44aeadbd84883f7403e9