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Autor:
Patrizia Fortini, Rea Legnaro, G. L. Scapoli, Donato Gemmati, Marcello Izzo, Silvia Tognazzo, Vincenzo Lanzara, Annunziata Palazzo, Paolo Zamboni
Publikováno v:
Dermatologic Surgery. 31:644-649
BACKGROUND. Severe chronic venous disease (CVD) is characterized by both dermal hemosiderin accumulation and matrix metalloproteinase (MMP) hyperactivation. The iron-driven pathway is one of the recognized mechanisms of MMP hyperactivation. OBJECTIVE