Výsledky vyhledávání - "Re-sensitization"

Akademický článek

LL37-Derived Fragments Improve the Antibacterial Potential of Penicillin G and Ampicillin against Methicillin-Resistant Staphylococcus aureus

Autor: Wenxu Han, Terri A. Camesano

Publikováno v: Antibiotics, Vol 12, Iss 9, p 1398 (2023)

Methicillin-resistant Staphylococcus aureus (MRSA) infections are a severe threat to public health. Antimicrobial peptides (AMPs) are novel and potential antimicrobials with specific antibacterial mechanisms. Our aim was to study the potential of LL3

Externí odkaz: https://doaj.org/article/b6c79c3427a34a01bc33f00a5d5d32bd

Zobrazit plný text záznamu

Akademický článek

A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors

Autor: Gabriele Manzella, Devmini C. Moonamale, Michaela Römmele, Peter Bode, Marco Wachtel, Beat W. Schäfer

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 929-938 (2021)

First-line therapy for most pediatric sarcoma is based on chemotherapy in combination with radiotherapy and surgery. A significant number of patients experience drug resistance and development of relapsed tumors. Drugs that have the potential to re-s

Externí odkaz: https://doaj.org/article/f1fc0a072c4b4d0eba59315f15d35947

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Exploring the Potential of CRISPR-Cas9 Under Challenging Conditions: Facing High-Copy Plasmids and Counteracting Beta-Lactam Resistance in Clinical Strains of Enterobacteriaceae

Autor: Thaysa Leite Tagliaferri, Natália Rocha Guimarães, Marcella de Paula Martins Pereira, Liza Figueiredo Felicori Vilela, Hans-Peter Horz, Simone Gonçalves dos Santos, Tiago Antônio de Oliveira Mendes

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

The antimicrobial resistance (AMR) crisis urgently requires countermeasures for reducing the dissemination of plasmid-borne resistance genes. Of particular concern are opportunistic pathogens of Enterobacteriaceae. One innovative approach is the CRIS

Externí odkaz: https://doaj.org/article/9476b8f3ff124249bb67992d7c896fb0

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Synergistic Killing and Re-Sensitization of Pseudomonas aeruginosa to Antibiotics by Phage-Antibiotic Combination Treatment

Autor: Emily Engeman, Helen R. Freyberger, Brendan W. Corey, Amanda M. Ward, Yunxiu He, Mikeljon P. Nikolich, Andrey A. Filippov, Stuart D. Tyner, Anna C. Jacobs

Publikováno v: Pharmaceuticals, Vol 14, Iss 3, p 184 (2021)

Multidrug-resistant (MDR) Pseudomonas aeruginosa infections pose a serious health threat. Bacteriophage–antibiotic combination therapy is a promising candidate for combating these infections. A 5-phage P. aeruginosa cocktail, PAM2H, was tested in c

Externí odkaz: https://doaj.org/article/d51e52722db14501aadfee3af03f8332

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors

Autor: Michaela Römmele, Devmini C. Moonamale, Peter K. Bode, Beat W. Schäfer, Marco Wachtel, Gabriele Manzella

Publikováno v: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 929-938 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c78d0a77e118c41a16f1f6e21233c5
http://europepmc.org/articles/PMC8329430

Zobrazit plný text záznamu

Akademický článek

Efficacia della combinazione lapatinib-capecitabina in una paziente con carcinoma mammario HER2-positivo metastatico e con resistenza primaria a due linee di terapia con agenti anti-HER2

Autor: Claudio Vernieri, Pietro Indelicato, Giuseppe Capri

Publikováno v: AboutOpen, Vol 3, Iss 1 (2017)

La sovraespressione dell’oncoproteina HER2 (human epidermal growth factor receptor 2), spesso sostenuta dall’amplificazione del corrispondente oncogene HER2, si verifica in circa il 15-20% dei carcinomi mammari ed è associata a una rapida cresci

Externí odkaz: https://doaj.org/article/6b6d6ffddaf5401eb8d1c5a8cb0e266d

Zobrazit plný text záznamu

Sensitizing and control of colistin-resistant E. coli O157:H7 with bacteriophage application

Autor: Gizem ÇUFAOĞLU, Naim Deniz AYAZ

Publikováno v: Volume: 40, Issue: 2 88-92
Journal of Research in Veterinary Medicine

In these days that we are drifting into the post-antibiotic era, antibiotics called "last-resort" are begun to be used more frequently. Colistin is one of the last-resort antibiotics that act on Gram-negative bacteria. The aim of the study was to inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c660c402c0eacb2ed0c7245bf589a375
https://dergipark.org.tr/tr/pub/jrvm/issue/67911/904155

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání