Výsledky vyhledávání

Akademický článek

Utility of needle biopsy in centrally located lung cancer for genome analysis: a retrospective cohort study

Autor: Kei Kunimasa, Shingo Matsumoto, Keiichiro Honma, Motohiro Tamiya, Takako Inoue, Takahisa Kawamura, Satoshi Tanada, Akito Miyazaki, Ryu Kanzaki, Tomohiro Maniwa, Jiro Okami, Yuji Matsumoto, Koichi Goto, Kazumi Nishino

Publikováno v: BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Background It is essential to collect a sufficient amount of tumor tissue for successful next-generation sequencing (NGS) analysis. In this study, we investigated the clinical risk factors for avoiding re-biopsy for NGS analysis (re-genome b

Externí odkaz: https://doaj.org/article/8068f32a5bac4be8b8a6cb9cbd42ca65

Zobrazit plný text záznamu

Akademický článek

Redetermination of PD-L1 expression after chemio-radiation in locally advanced PDL1 negative NSCLC patients: retrospective multicentric analysis

Autor: Patrizia Ciammella, Salvatore Cozzi, Paolo Borghetti, Marco Galaverni, Valerio Nardone, Maria Paola Ruggieri, Matteo Sepulcri, Vieri Scotti, Alessio Bruni, Francesca Zanelli, Roberto Piro, Elena Tagliavini, Andrea Botti, Federico Iori, Emanuele Alì, Chiara Bennati, Marcello Tiseo

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

BackgroundChemoradiation therapy (CRT) is the treatment of choice for locally advanced non-small cell lung cancer (LA-NSCLC). Several clinical trials that combine programmed cell death 1 (PD1) axis inhibitors with radiotherapy are in development for

Externí odkaz: https://doaj.org/article/5295884ae5854ba4ba4dd0e47e0a1c72

Zobrazit plný text záznamu

Akademický článek

Endobronchial ultrasound‐guided re‐biopsy of non–small cell lung cancer with acquired resistance after EGFR tyrosine kinase inhibitor treatment

Autor: Kyung Soo Hong, Jinmo Cho, Jong Geol Jang, Min Hye Jang, June Hong Ahn

Publikováno v: Thoracic Cancer, Vol 14, Iss 4, Pp 363-370 (2023)

Abstract Background Few studies assessed the use of endobronchial ultrasound (EBUS)‐guided re‐biopsy for detecting the T790M mutation after epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) failure. Methods A total of 2996

Externí odkaz: https://doaj.org/article/9377bd5e7d444351bfe3995c96b9286f

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Comparison of sampling methods for next generation sequencing for patients with lung cancer

Autor: Kei Kunimasa, Shingo Matsumoto, Kazumi Nishino, Keiichiro Honma, Noboru Maeda, Hanako Kuhara, Motohiro Tamiya, Takako Inoue, Takahisa Kawamura, Toru Kimura, Tomohiro Maniwa, Jiro Okami, Koichi Goto, Toru Kumagai

Publikováno v: Cancer Medicine, Vol 11, Iss 14, Pp 2744-2754 (2022)

Abstract Introduction Success of next generation sequencing (NGS) analysis is becoming indispensable in the treatment of advanced lung cancer. However, the advantages and disadvantages of each sampling method in the NGS analysis have not yet been cla

Externí odkaz: https://doaj.org/article/978e7bbf0f754bd9ad62e1525b8d6435

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Factors associated with outcomes of second-line treatment for EGFR-mutant non-small-cell lung cancer patients after progression on first- or second-generation EGFR-tyrosine kinase inhibitor treatment

Autor: Cheng-Yu Chang, Chung-Yu Chen, Shih-Chieh Chang, Ching-Yi Chen, Yi-Chun Lai, Chun-Fu Chang, Yu-Feng Wei

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

PurposeEpidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are standard first-line treatments for advanced EGFR-mutant non-small-cell lung cancer (NSCLC) patients. However, factors associated with outcomes after progression on fir

Externí odkaz: https://doaj.org/article/cc725836f1ea450cad1180c1b6ccc8d3

Zobrazit plný text záznamu

Akademický článek

RET fusion mutation detected by re-biopsy 7 years after initial cytotoxic chemotherapy: A case report

Autor: Kei Morikawa, Hiroshi Handa, Junko Ueno, Hajime Tsuruoka, Takeo Inoue, Naoki Shimada, Junki Koike, Seiji Nakamura, Yoshiharu Sato, Masamichi Mineshita

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Personalized medicine using molecular-targeted drugs to achieve better therapeutic response and long-term prognosis is common practice for lung cancer treatment. However, in cases before gene batch tests were available, medical treatment continued wi

Externí odkaz: https://doaj.org/article/b35eccb4ac88451ca4ff253309612c9f

Zobrazit plný text záznamu

Akademický článek

Comparison of Different EGFR Gene Mutation Status in Patients with Metastatic Non-Small Lung Cancer After First-Line EGFR-TKIs Therapy and Analyzing Its Relationship with Efficacy and Prognosis

Autor: Yuan C, Jiang H, Jiang W, Wang H, Su C, Zhou S

Publikováno v: Cancer Management and Research, Vol Volume 13, Pp 6901-6910 (2021)

Chengliang Yuan, Huiqin Jiang, Wei Jiang, Huilin Wang, Cuiyun Su, Shaozhang Zhou Department of Respiratory Oncology, Guangxi Medical University Affiliated Tumor Hospital, Nanning City, Guangxi Zhuang Autonomous Region, 530021, People’s Republic of

Externí odkaz: https://doaj.org/article/5f22cd6f9b4b4626a9d2ae8c33a1e87e

Zobrazit plný text záznamu

Akademický článek

Next‐generation sequencing of tissue and circulating tumor DNA: Resistance mechanisms to EGFR targeted therapy in a cohort of patients with advanced non‐small cell lung cancer

Autor: Yujun Zhang, Liwen Xiong, Fangfang Xie, Xiaoxuan Zheng, Ying Li, Lei Zhu, Jiayuan Sun

Publikováno v: Cancer Medicine, Vol 10, Iss 14, Pp 4697-4709 (2021)

Abstract Background Epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) has been considered as an effective treatment in epidermal growth factor receptor‐mutant (EGFR‐mutant) advanced non‐small cell lung cancer (NSCLC). Ho

Externí odkaz: https://doaj.org/article/5c3e068d5b63440ea56537f44a299edc

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání