Výsledky vyhledávání

Akademický článek

Leishmania Parasite Subunit Vaccine in HLA-A2 Transgenic Mouse Model

Autor: H Rezvan, SA Ali, RC Rees

Publikováno v: Iranian Journal of Public Health, Vol 34, Iss Supple 1 (2005)

In the last few decades, parasitic infections have created a major human health problem across the world. In developing countries the problem is beyond control and the number of new cases is on a continuous rise. Leishmaniasis is a tropical disease a

Externí odkaz: https://doaj.org/article/54bda982f05c4b6e8b29fe05b2519d0b

Zobrazit plný text záznamu

Preclinical evaluation of 'whole' cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes

Autor: Sa, Ali, Cs, Mclean, Mike Boursnell, Martin G, Cl, Holmes, Reeder S, Entwisle C, Dm, Blakeley, Jg, Shields, Todryk S, Vile R, Ra, Robins, Rc, Rees

Publikováno v: Europe PubMed Central

The development of genetically modified "whole" tumor cell vaccines for cancer therapy relies on the efficient transduction and expression of genes by vectors. In the present study, we have used a disabled infectious single cycle-herpes simplex virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6176b09d279e08ced01b6468bcce6212
https://pubmed.ncbi.nlm.nih.gov/10749137

Zobrazit plný text záznamu

Interleukin-2-activated human effector lymphocytes mediate cytotoxicity by inducing apoptosis in human leukaemia and solid tumour target cells

Autor: Cr, Knight, Rc, Rees, Platts A, Johnson T, Martin Griffin

Publikováno v: Europe PubMed Central

The mode of cytotoxic action employed by cytolytic lymphocytes remains unclear, with the possibility of several mechanisms being utilized dependent upon the activation state of the effector cell. In this work, the induction of apoptosis in target cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a877a00e3228c90b4cb0e0df24a82a2
https://pubmed.ncbi.nlm.nih.gov/8104887

Zobrazit plný text záznamu

The identification of factors in seminal plasma responsible for suppression of natural killer cell activity

Autor: Pamela Vallely, Rm, Sharrard, Rc, Rees

Publikováno v: Europe PubMed Central

We have identified two components of human seminal plasma which suppress natural killer (NK) cell activity in vitro. Dialysis and gel filtration experiments have shown both components to be of low molecular weight. The first will suppress NK cells fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::31d491b44f74d7245df08adbd8cedeb6
https://pubmed.ncbi.nlm.nih.gov/3350580

Zobrazit plný text záznamu

Cancer/testis antigens for therapeutic use

Autor: Mg, Mathieu, Ak, Miles, Li G, Stephanie McArdle, Rc, Rees

Publikováno v: Europe PubMed Central

Since van der Bruggen and colleagues first identified specific human tumour-associated antigens of the MAGE family, numerous potential immunotherapeutic targets have been discovered, often belonging to the so-called cancer/ testis gene family. Severa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8ff8bc2b61d03f8d0bc24ded0f2c4814
http://europepmc.org/abstract/med/19785076

Zobrazit plný text záznamu

Transfection of tissue transglutaminase into a highly malignant hamster fibrosarcoma leads to a reduced incidence of primary tumour growth

Autor: Ts, Johnson, Cr, Knight, el-Alaoui S, Mian S, Rc, Rees, Gentile V, Pj, Davies, Martin Griffin

Publikováno v: Europe PubMed Central

Reduced expression of the tissue transglutaminase in both murine and human tumours has been consistently associated with tumour growth and progression. To investigate the functional effects of transglutaminase expression we have transfected a constit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dc3a1cefc9422cd04892ae83c96cbd22
http://europepmc.org/abstract/med/7916148

Zobrazit plný text záznamu

Identification of the 72-kDa (MMP-2) and 92-kDa (MMP-9) gelatinase/type IV collagenase in preparations of laminin and Matrigel

Autor: Andrew Reay Mackay, Gomez DE, Dw, Cottam, Rc, Rees, Am, Nason, Up, Thorgeirsson

Publikováno v: Europe PubMed Central

EDTA inhibitable type IV collagenolytic activity copurified with laminin preparations from the Engelbreth-Holm-Swarm (EHS) tumor. Several gelatinolytic and type IV collagenolytic matrix metalloproteinase (MMP) species were visualized in EHS laminin f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8aee4e4e916a25609780938db2dbf4d9
http://europepmc.org/abstract/med/8292337

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání