Zobrazeno 1 - 10
of 4 510
pro vyhledávání: '"Rb1"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4825-4838 (2024)
Yi Zhou,1 Xinyu Xiong,1 Zhe Cheng,1 Zekai Chen,1 Shizhen Wu,2 Yan Yu,3 Yujin Liu,4 Guang Chen,1 Lingli Li5 1Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and
Externí odkaz:
https://doaj.org/article/df6992f2b4bc46e98a6b69b9227e1c1a
Autor:
Yue Chen, Kang-xi Zhang, Hui Liu, Yue Zhu, Qing-yun Bu, Shu-xia Song, Ya-chun Li, Hong Zou, Xiao-yan You, Guo-ping Zhao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Ginsenoside Rb1 exhibits a wide range of biological activities, and gut microbiota is considered the main metabolic site for Rb1. However, the impact of gut microbiota on the pharmacokinetics of Rb1 are still uncertain. In this study, we inv
Externí odkaz:
https://doaj.org/article/0ad6070f49cd4be8a247478ec9a1c7ea
Autor:
Hui Wang, Yue Zhu, Pengcheng Shi, Xiangyang Li, Qingyun Bu, Yachun Li, Xiaoyan You, Guoping Zhao
Publikováno v:
Engineered Regeneration, Vol 5, Iss 3, Pp 283-294 (2024)
Non-alcoholic fatty liver disease (NAFLD), a type of liver disease for which no treatment is currently approved, remains a major concern worldwide. It is manifested as simple hepatocyte steatosis and can develop into inflammation, fibrosis, cirrhosis
Externí odkaz:
https://doaj.org/article/cef7701ae10a4841928d2f00b68ee5f2
Autor:
Jing Zhou, Qing Song, Haoze Li, Yicun Han, Yunzhou Pu, Ling Li, Wenqing Rong, Xiaodie Liu, Ziyuan Wang, Jian Sun, Yuqing Song, Xueyan Hu, Guanghao Zhu, Huirong Zhu, Liu Yang, Guangbo Ge, Hongshan Li, Qing Ji
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Background Information transmission between primary tumor cells and immunocytes or stromal cells in distal organs is a critical factor in the formation of pre-metastatic niche (PMN). Understanding this mechanism is essential for developing e
Externí odkaz:
https://doaj.org/article/ec9cf269f99d490988b8549851e4f1e7
Autor:
Ting Lei, Zhiyi Shen, Mengjia Shen, Lingfang Du, Yongqiang Shi, Yan Peng, Zidi Zhou, Wenyue Da, Xi Chen, Qing Li
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Aims Compared to primary breast sarcoma (BSs), radiotherapy-induced sarcoma (RIS) is a less frequent type of secondary breast sarcoma. Undifferentiated pleomorphic sarcoma (UPS) is an even rarer occurrence within the RIS category. This study
Externí odkaz:
https://doaj.org/article/4d69b1d7e0d646ef8704352bcc5048de
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 10, Pp n/a-n/a (2024)
ABSTRACT We report a case of 59‐year‐old female with solitary bilateral renal metastases after surgery of stage IA primary lung adenocarcinoma who underwent next‐generation sequencing (NGS) of both lesions. The patient received right upper lobe
Externí odkaz:
https://doaj.org/article/284dfb15f8e64a2ab56d6abfefc7fa74
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Combined large cell neuroendocrine carcinoma (CLCNEC) is a rare neuroendocrine carcinoma, accounting for approximately 10% of large cell neuroendocrine carcinoma (LCNEC). Mainly composed of coexisting adenocarcinoma components, with strong invasivene
Externí odkaz:
https://doaj.org/article/52c72d394cc14737bb315068dab193d0
Publikováno v:
Shipin yu jixie, Vol 40, Iss 7, Pp 1-6,80 (2024)
[Objective] β-Sitosterol-modified ginsenoside Rb1 liposomes （β-Rb1-Lip） were prepared to reduce the degradation of Rb1 and enhance the lipid-lowering effects of ginsenoside Rb1. [Methods] β-sitosterol-modified ginsenoside Rb1 liposomes were pr
Externí odkaz:
https://doaj.org/article/1df0b73588c24ece84cfafb36b4f9bca
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Aging brings about physiological dysfunction, disease, and eventual mortality. An increasing number of studies indicate that aging can easily lead to dysbiosis of the gut microbiota, which can further affect digestion, nerves, cognition, emotions, an
Externí odkaz:
https://doaj.org/article/cd4784f7bfe2409fa520eb4154f4e488
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5307-5321 (2024)
Retinoblastoma (RB) is the most common intraocular malignant tumor in children, primarily attributed to the bi-allelic loss of the RB1 gene in the developing retina. Despite significant progress in understanding the basic pathogenesis of RB, comprehe
Externí odkaz:
https://doaj.org/article/618fb25bc21c4fad814e767c9eb89436