Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Razi Raziuddin"'
Autor:
Diana A. Stavreva, Lyuba Varticovski, Razi Raziuddin, Gianluca Pegoraro, R. Louis Schiltz, Gordon L. Hager
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Progesterone receptor (PR)-interacting compounds in the environment are associated with serious health hazards. However, methods for their detection in environmental samples are cumbersome. We report a sensitive activity-based biosensor for
Externí odkaz:
https://doaj.org/article/22d46109ab134ab3baf024db0dc843bd
Publikováno v:
Mol Cell Endocrinol
Sex hormones, such as androgens, estrogens and progestins are naturally occurring compounds that tightly regulate endocrine systems in a variety of living organisms. Uncontrolled environmental exposure to these hormones or their biological and synthe
Autor:
Razi Raziuddin, Michael R. Collins, Nicholas Mazza, David Owen Brody, Gianluca Pegoraro, Riley Kuehn, Gordon L. Hager, Johnna Lee, Jerry Zhao, Diana A. Stavreva, Andrew McGowan, Lyuba Varticovski, Elisabeth Dehareng
Publikováno v:
Sci Total Environ
Water sources are frequently contaminated with natural and anthropogenic substances having known or suspected endocrine disrupting activities; however, these activities are not routinely measured and monitored. Phenotypic bioassays are a promising ne
Publikováno v:
Journal of the Endocrine Society
The presence of progesterone receptor (PR)-interacting compounds in the environment may have serious health consequences for humans and wildlife, but the methods for their detection and monitoring are limited. Here we report the development and testi
Autor:
Gordon L. Hager, Jinghua Zhao, Keith A. Houck, Vikas Soni, Menghang Xia, Katie Paul-Friedman, Diana A. Stavreva, Kevin M. Crofton, Chia-Wen Hsu, Ruili Huang, Srilatha Sakamuru, Razi Raziuddin, Matthew T. Martin, Lyuba Varticovski
Publikováno v:
Environmental Health Perspectives
Thyroid hormone receptors (TRs) are critical endocrine receptors that regulate a multitude of processes in adult and developing organisms, and thyroid hormone disruption is of high concern for neurodevelopmental and reproductive toxicities in particu
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Biological Chemistry. 272:15715-15720
The c-erbB-2 gene overexpression plays a major role in the pathogenesis of breast cancer. Binding studies detected a nuclear matrix protein (NMP) in human breast tumor tissues that recognizes a matrix attachment region (MAR) in the immediate vicinity
Publikováno v:
Molecular and cellular biology. 24(15)
Regulation of cell polarity is an important biological event that governs diverse cell functions such as localization of embryonic determinants and establishment of tissue and organ architecture. The Rho family GTPases and the polarity complex Par6/P
Publikováno v:
Molecular biology of the cell. 15(3)
Dynamic rearrangements of cell-cell adhesion underlie a diverse range of physiological processes, but their precise molecular mechanisms are still obscure. Thus, identification of novel players that are involved in cell-cell adhesion would be importa