Zobrazeno 1 - 10
of 1 651
pro vyhledávání: '"Razelle, Kurzrock"'
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 4, Pp 308-313 (2024)
Clear cell renal cell carcinoma (RCC) is commonly associated with alterations in the VHL tumor suppressor gene, resulting in upregulation of hypoxia-inducible factor pathways. Immune checkpoint inhibitors and vascular endothelial growth factor inhibi
Externí odkaz:
https://doaj.org/article/103472f66bf64b72b22ea23036068dfb
Autor:
Yuji Uehara, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mary K. Nesline, Sarabjot Pabla, Jeffrey M. Conroy, Paul DePietro, Heidi Ko, Jason K. Sicklick, Razelle Kurzrock
Publikováno v:
Cancer Communications, Vol 44, Iss 10, Pp 1168-1172 (2024)
Externí odkaz:
https://doaj.org/article/0d1f115fc5604621bd3058b976a0f2cb
Autor:
Eylül Özgü, Benjamin G. Kaplan, Smruthy Sivakumar, Ethan S. Sokol, Esranur Aydın, Ünal Metin Tokat, Ashkan Adibi, Ebru Gül Karakoç, Jiancheng Hu, Razelle Kurzrock, Mutlu Demiray
Publikováno v:
BJC Reports, Vol 2, Iss 1, Pp 1-11 (2024)
Abstract Background Kinase-impaired class III BRAF mutations have recently received attention as a possible prognostic factor and therapeutic target. Class III BRAF variants differ from class I and class II mutations in terms of mechanism of pathway
Externí odkaz:
https://doaj.org/article/e40e1f2264f54e588f65d74290b386b7
Autor:
Razelle Kurzrock, David Hong
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 3, Pp 142-149 (2024)
Externí odkaz:
https://doaj.org/article/b72f8eca07294c1fb7a14cf64660fbda
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 3, Pp 201-204 (2024)
A 62-year-old man presented with a slowly growing, painless lesion on his face. This eventually led to a progressive left-eye vision lesion, and the patient was subsequently diagnosed with advanced basal cell carcinoma (BCC). Of note, BCC involving c
Externí odkaz:
https://doaj.org/article/5348ff1013384017b4b6573d58654f31
Autor:
Vladimir Lazar, Eric Raymond, Shai Magidi, Catherine Bresson, Fanny Wunder, Ioana Berindan-Neagoe, Annemilaï Tijeras-Rabaland, Jacques Raynaud, Amir Onn, Michel Ducreux, Gerald Batist, Ulrik Lassen, Fin Cilius Nielsen, Richard L. Schilsky, Eitan Rubin, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Dysregulated pathways in cancer may be hub addicted. Identifying these dysregulated networks for targeting might lead to novel therapeutic options. Objective: Considering the hypothesis that central hubs are associated with increased leth
Externí odkaz:
https://doaj.org/article/da12cb09d31d4454bd2113b0c027167a
Autor:
Howard Streicher, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Megan Othus, Sandip Patel, Christine McLeod, Charles Blanke, Benjamin Powers, Chung-Tsen Hsueh, Helen X Chen, Hye Sung Kim, Liam Il-Young Chung, Christopher W Ryan, Rangaswamy Govindarajan, Silvana Bucur
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Dual inhibition using anti-programmed death-1 (PD-1) and anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) checkpoint inhibitors has proven effective in many cancers. However, its efficacy in rare solid cancers remains unclear. Desmoid tumors
Externí odkaz:
https://doaj.org/article/ae531706fd0f41aba22cfb80da0bf6da
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 2, Pp 122-125 (2024)
ABSTRACT: Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder that primarily causes the growth of tumors alongnerves. Additionally, the germline mutations involved in NF1 predispose patients to develop further malignancies. The m
Externí odkaz:
https://doaj.org/article/9383a44b830f4e848e207ffe267ac387
Multi‐omic analysis in carcinoma of unknown primary (CUP): therapeutic impact of knowing the unknown
Autor:
Shumei Kato, Sophia Gumas, Jacob J. Adashek, Ryosuke Okamura, Suzanna Lee, Jason K. Sicklick, Razelle Kurzrock
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 956-968 (2024)
Carcinoma of unknown primary (CUP) is a difficult‐to‐manage malignancy. Multi‐omic profiles and treatment outcome vs. degree of precision matching were assessed. Tumours underwent next‐generation sequencing (NGS) [tissue and/or blood‐derive
Externí odkaz:
https://doaj.org/article/2f709749a5e648c68c0ec4e1799e0aa3
Autor:
Ashwin V. Kammula, Alejandro A. Schäffer, Padma Sheila Rajagopal, Razelle Kurzrock, Eytan Ruppin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Identifying sex differences in outcomes and toxicity between males and females in oncology clinical trials is important and has also been mandated by National Institutes of Health policies. Here we analyze the Trialtrove database, finding th
Externí odkaz:
https://doaj.org/article/8acb05eafc104689960ff4f9ac428631