The role of glycolysis-derived hexose phosphates in the induction of the Crabtree effect

Autor: Noureddine Hammad, Razanne Issa, Alexis Mougeolle, Elodie Roussarie, Mónica Rosas Lemus, Stéphane Ransac, Salvador Uribe-Carvajal, Michel Rigoulet, Anne Devin, Jean-Pierre Mazat

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2018, 293 (33), pp.12843-12854. ⟨10.1074/jbc.RA118.003672⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (33), pp.12843-12854. ⟨10.1074/jbc.RA118.003672⟩

Evidence for the Crabtree effect was first reported by H. Crabtree in 1929 and is defined as the glucose-induced decrease of cellular respiratory flux. This effect was observed in tumor cells and was not detected in most non-tumor cells. A number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf96db0cb4a8b88e98643562f5b24be
https://doi.org/10.1074/jbc.ra118.003672

Human-Scale Metabolic Network of Central Carbon Metabolism: application to serine metabolism from glutamine in Cancer Cells

Autor: Bertrand Beauvoit, Sophie Colombie, Razanne Issa, Jean-Pierre Mazat, Christine Nazaret, Sabine Peres

Publikováno v: advances in Systems and Synthetic Biology
advances in Systems and Synthetic Biology, Mar 2016, Evry, France
HAL

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::10323a0a643760905813c3c0e8cecffb
https://hal.archives-ouvertes.fr/hal-01709760