Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Raz Bar-Ziv"'
Autor:
Phillip A. Frankino, Talha F. Siddiqi, Theodore Bolas, Raz Bar-Ziv, Holly K. Gildea, Hanlin Zhang, Ryo Higuchi-Sanabria, Andrew Dillin
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104571- (2022)
Summary: The deleterious potential to generate oxidative stress is a fundamental challenge to metabolism. The oxidative stress response transcription factor, SKN-1/NRF2, can sense and respond to changes in metabolic state, although the mechanism and
Externí odkaz:
https://doaj.org/article/b8b1723357a2408287e1e54de8221cc9
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 3989-3995.e4 (2020)
Summary: Genome replication perturbs the DNA regulatory environment by displacing DNA-bound proteins, replacing nucleosomes, and introducing dosage imbalance between regions replicating at different S-phase stages. Recently, we showed that these effe
Externí odkaz:
https://doaj.org/article/93907fe0f7c648898f48ea45c662de54
Autor:
Idan Frumkin, Ido Yofe, Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek, Ruth Towers, Dvir Schirman, Heike Krebber, Yitzhak Pilpel
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000423 (2019)
Splicing expands, reshapes, and regulates the transcriptome of eukaryotic organisms. Despite its importance, key questions remain unanswered, including the following: Can splicing evolve when organisms adapt to new challenges? How does evolution opti
Externí odkaz:
https://doaj.org/article/6c40cee53baf4283b3193a27124621e8
Autor:
Gilberto Garcia, Raz Bar‐Ziv, Maxim Averbukh, Nirmalya Dasgupta, Naibedya Dutta, Hanlin Zhang, Wudi Fan, Darius Moaddeli, C. Kimberly Tsui, Toni Castro Torres, Athena Alcala, Erica A. Moehle, Sally Hoang, Ophir Shalem, Peter D. Adams, Max A. Thorwald, Ryo Higuchi‐Sanabria
Publikováno v:
Aging Cell. 22
The actin cytoskeleton is a three-dimensional scaffold of proteins that is a regulatory, energyconsuming network with dynamic properties to shape the structure and function of the cell. Proper actin function is required for many cellular pathways, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a352d384513a57fdd6ede998a1135f5a
https://doi.org/10.1111/acel.13742
https://doi.org/10.1111/acel.13742
Autor:
Holly K. Gildea, Melissa G. Metcalf, Ashley E. Frakes, Sarah U. Tronnes, Jenni Durieux, Andrew Dillin, Samira Monshietehadi, Nazineen Kandahari, Raz Bar-Ziv
Publikováno v:
Science
Science (New York, N.Y.), vol 367, iss 6476
Science (New York, N.Y.), vol 367, iss 6476
Taking the stress out of life In the model organism Caenorhabditis elegans , a roundworm, it has been shown that neurons can communicate proteostasis to the periphery to affect aging. Frakes et al. have now identified astrocytelike glial cells that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908b8e02f6b8df8664eca7c5e542cf43
https://doi.org/10.1126/science.aaz6896
https://doi.org/10.1126/science.aaz6896
Autor:
Phillip A. Frankino, Talha F. Siddiqi, Theodore Bolas, Raz Bar-Ziv, Holly K. Gildea, Hanlin Zhang, Ryo Higuchi-Sanabria, Andrew Dillin
SUMMARYThe deleterious potential to generate oxidative stress and damage is a fundamental challenge to metabolism. The oxidative stress response transcription factor, SKN-1/NRF2, can sense and respond to changes in metabolic state, although the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f63d9254eba711f79c4407e3eddac36
https://doi.org/10.1101/2022.02.03.479044
https://doi.org/10.1101/2022.02.03.479044
Autor:
Raz, Bar-Ziv, Ashley E, Frakes, Ryo, Higuchi-Sanabria, Theodore, Bolas, Phillip A, Frankino, Holly K, Gildea, Melissa G, Metcalf, Andrew, Dillin
Publikováno v:
J Vis Exp
Organisms are often exposed to fluctuating environments and changes in intracellular homeostasis, which can have detrimental effects on their proteome and physiology. Thus, organisms have evolved targeted and specific stress responses dedicated to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d7ac4fdf76132095617acb46fbeaad9
https://pubmed.ncbi.nlm.nih.gov/32510480
https://pubmed.ncbi.nlm.nih.gov/32510480
Autor:
Samira Monshietehadi, Liza A. Pon, Jenni Durieux, Melissa Sanchez, Rui Wu, Sarah U. Tronnes, Sofia Dallarda, Phillip A. Frankino, Roberto Zoncu, Larry Joe, Raz Bar-Ziv, Enrique J. Garcia, Andrew Dillin, Corinne Pender, Koning Shen, Brant Michael Webster, Ryo Higuchi-Sanabria, Stefan Homentcovschi, Alex Ahilon-Jeronimo, Cierra N. Sing, Naame Kelet
Publikováno v:
Science Advances
Science advances, vol 6, iss 26
Science advances, vol 6, iss 26
The lysosome affects ER homeostasis by recycling critical amino acids.
Recent work has highlighted the fact that lysosomes are a critical signaling hub of metabolic processes, providing fundamental building blocks crucial for anabolic functions.
Recent work has highlighted the fact that lysosomes are a critical signaling hub of metabolic processes, providing fundamental building blocks crucial for anabolic functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9073a4ed82122578fc495de35e2130c3
http://europepmc.org/articles/PMC7319768
http://europepmc.org/articles/PMC7319768
Publikováno v:
EMBO Rep
Multicellular organisms are complex biological systems, composed of specialized tissues that require coordination of the metabolic and fitness state of each component. In the cells composing the tissues, one central organelle is the mitochondrion, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34db4af40cc51e90ad84ff5ea8b08e94
https://doi.org/10.15252/embr.202050094
https://doi.org/10.15252/embr.202050094
SummaryGenome replication perturbs the DNA regulatory environment by displacing DNA-bound proteins, replacing nucleosomes, and introducing dosage-imbalance between regions replicating at different S phase stages. Recently, we showed that these effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfaa6d0eba3bd6984ea83a84e5fa0fc