Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rayra P. Santiago"'
Autor:
Rayra P. Santiago, Magda O. S. Carvalho, Camylla V. B. Figueiredo, Luciana M. Fiuza, Rodrigo M. Oliveira, Sètondji C. M. A. Yahouédéhou, Valma M. L. Nascimento, Isa M. Lyra, Théo Araujo-Santos, Nívea F. Luz, Milena M. Aleluia, Caroline C. Guarda, Valéria M. Borges, Marilda S. Goncalves
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Transforming growth factor beta (TGF-β) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease (SCD), including endothelial and vascular dysfunction, inflammation, and hematopoietic homeos
Externí odkaz:
https://doaj.org/article/892c705b9cbd49e4a9629b06f20715bc
Autor:
Rayra P. Santiago, Camylla V. B. Figueiredo, Luciana M. Fiuza, Sètondji C. M. A. Yahouédéhou, Rodrigo M. Oliveira, Milena M. Aleluia, Suellen P. Carvalho, Cleverson A. Fonseca, Valma M. L. Nascimento, Larissa C. Rocha, Caroline C. Guarda, Marilda S. Gonçalves
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Po
Externí odkaz:
https://doaj.org/article/f35c42e4663747afa18f399a54be5dfd
Autor:
Joelma Figueiredo Menezes, Magda Oliveira Seixas Carvalho, Larissa Carneiro Rocha, Felipe Miranda dos Santos, Elisângela Vitória Adorno, Cyntia Cajado de Souza, Rayra Pereira Santiago, Caroline Conceição da Guarda, Rodrigo Mota de Oliveira, Camylla Vilas Boas Figueiredo, Suéllen Pinheiro Carvalho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Luciana Magalhães Fiuza, Corynne Stéphanie Ahouefa Adanho, Thassila Nogueira Pitanga, Isa Menezes Lyra, Valma Maria Lopes Nascimento, Alberto Augusto Noronha-Dutra, Marilda Souza Goncalves
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Sickle cell disease (SCD) patients often exhibit a dyslipidemic sub-phenotype. Paraoxonase 1 (PON 1) is a serum glycoprotein associated with the high-density lipoproteins cholesterol (HDL-C), and variability in PON1 activity depends on the P
Externí odkaz:
https://doaj.org/article/d3ca186186fb49ce9f36b6457163e292
Autor:
Edvan do Carmo Santos, Paulo Vinícius Bispo Santana, Laíne Lopes Silva de Jesus, Gabriela Imbassahy Valentim Melo, Sètondji Cocou Modeste Alexandre Yahouédéhou, Caroline Conceição da Guarda, Rayra Pereira Santiago, Luciana Magalhães Fiuza, Suéllen Pinheiro Carvalho, Liz Oliveira dos Santos, Elisângela Vitória Adorno, Augusto Cezar Magalhães Aleluia, Luciene Cristina Gastalho Campos Luiz, Teresa Cristina Cardoso Fonseca, Marilda de Souza Gonçalves, Milena Magalhães Aleluia
Publikováno v:
Hematology Reports, Vol 15, Iss 1, Pp 119-129 (2023)
Sickle cell disease (SCD) is characterized by the presence of the variant S hemoglobin (HbS). The homozygous genotype (HbSS) is sickle cell anemia (SCA), while the double heterozygous of HbS and HbC (HbSC) is defined as SC hemoglobinopathy. The patho
Externí odkaz:
https://doaj.org/article/7b6fd16d69e34155add7f5c83a6fb970
Autor:
Corynne Stéphanie Ahouéfa Adanho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Sânzio Silva Santana, Camilo Vieira, Rayra Pereira Santiago, Jeanne Machado de Santana, Thassila Nogueira Pitanga, Milena Magalhães Aleluia, Vítor Valério Maffili, Ivana Paula Ribeiro Leite, Dalila Luciola Zanette, Isa Menezes Lyra, Marilda Souza Goncalves
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundStroke is one of the highest complications of sickle-cell anemia (SCA). The Transcranial Doppler (TCD) has been adopted worldwide as a gold standard method for detecting alterations in the blood velocity in cerebral arteries. In this study,
Externí odkaz:
https://doaj.org/article/66b9dd24a8834b4fa171ac6e97b695b1
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Joelma Santana dos Santos Neres, Caroline Conceição da Guarda, Suellen Pinheiro Carvalho, Rayra Pereira Santiago, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Corynne Stéphanie Ahouéfa Adanho, Tiago Santos Carvalho da Rocha, Elisângela Vitória Adorno, Marilda Souza Goncalves
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Differences in hydroxyurea response in sickle cell anemia may arise due to a series of factors with genetic factors appearing to be predominant. This study aims to investigate the effects of single nucleotide polymorphisms in genes encoding drug-meta
Externí odkaz:
https://doaj.org/article/3400dd841545442395b4388443304024
Autor:
Milena Magalhães Aleluia, Caroline Conceição da Guarda, Rayra Pereira Santiago, Teresa Cristina Cardoso Fonseca, Fábia Idalina Neves, Regiana Quinto de Souza, Larissa Alves Farias, Felipe Araújo Pimenta, Luciana Magalhães Fiuza, Thassila Nogueira Pitanga, Júnia Raquel Dutra Ferreira, Elisângela Vitória Adorno, Bruno Antônio Veloso Cerqueira, Marilda de Souza Gonçalves
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Sickle cell anemia (SCA) patients exhibit sub-phenotypes associated to hemolysis and vaso-occlusion. The disease has a chronic inflammatory nature that has been also associated to alterations in the lipid profile. This study aims
Externí odkaz:
https://doaj.org/article/ed208174616147b98497bfe5fbf4bacb
Autor:
Magda Oliveira Seixas Carvalho, André Luís Carvalho Santos Souza, Mauricio Batista Carvalho, Ana Paula Almeida Souza Pacheco, Larissa Carneiro Rocha, Valma Maria Lopes do Nascimento, Camylla Vilas Boas Figueiredo, Caroline Conceição Guarda, Rayra Pereira Santiago, Adekunle Adekile, Marilda de Souza Goncalves
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Alpha-1 antitrypsin (AAT) is an inhibitor of neutrophil elastase and a member of the serine proteinase inhibitor (serpin) superfamily, and little is known about its activity in sickle cell disease (SCD). We hypothesize that AAT may undergo changes in
Externí odkaz:
https://doaj.org/article/9085d13e4a4646f1bcf962433de67878
Autor:
Thassila N, Pitanga, Sânzio S, Santana, Dalila L, Zanette, Caroline C, Guarda, Rayra P, Santiago, Vitor V, Maffili, Jonilson B, Lima, Graziele Q, Carvalho, Jaime R, Filho, Junia R D, Ferreira, Milena M, Aleluia, Valma M L, Nascimento, Magda O S, Carvalho, Isa M, Lyra, Valéria M, Borges, Ricardo R, Oliveira, Marilda S, Goncalves
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 70(7)
This study tested the hypothesis that sickle red blood cell (SS-RBC) can induce inflammasome NLRP3 components gene expression in peripheral blood mononuclear cells (PBMCs) as well as interleukin-1β (IL-1β) and leukotriene B4 (LTB4) production. Addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::084dc9ba7eb9233efaeab9a8272ff82c
https://pubmed.ncbi.nlm.nih.gov/34196737
https://pubmed.ncbi.nlm.nih.gov/34196737
Autor:
Rayra P. Santiago, Oliveira, Rodrigo M., Soares, Leonardo F., Camylla V. B. Figueiredo, Silva, Denise Oliveira, Hurtado-Guerrero, Ana F., Fiuza, Luciana M., Guarda, Caroline C., Elisângela V. Adorno, Cynara G. Barbosa, Marilda S. Gonçalves
Brazilian Quilombolas are communities composed of African-derived populations that have their territories guaranteed by the Brazilian Constitution. The present study investigated the hemoglobin (Hb) variants among these population groups. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a18967ae6c9e0a7c8d75b2525c3924e
