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Autor:
Raynard Forte, Barbara J. Taylor, Adorjan Aszalos, Michael M. Gottesman, Jien-Wei Zhou, Jun-Jie Yin, Michael P. Kozar, Xing-Jie Liang, Paul C. Wang, Carol O. Cardarelli
Publikováno v:
Experimental Cell Research. 293:283-291
The mechanism of resistance of cancer cells to the anticancer drug cisplatin is not fully understood. Using cisplatin-sensitive KB-3-1 and -resistant KCP-20 cells, we found that the resistant cells have higher membrane potential, as determined by mem