Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Raymund J, Wellinger"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 127-143 (2023)
Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In humans, 90%–95% of multi-exon genes produce alternatively spliced RNA transcripts. Therefore, every single gene has the opportunity of producing multiple
Externí odkaz:
https://doaj.org/article/2c240e6eb91746d4bea9ca5bb3922174
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113565- (2023)
Summary: The telomerase ribonucleoprotein particle (RNP) replenishes telomeric DNA and minimally requires an RNA component and a catalytic protein subunit. However, telomerase RNP maturation is an intricate process occurring in several subcellular co
Externí odkaz:
https://doaj.org/article/93f61ec883d9483b8fe0d1d9a1c11363
Autor:
Laetitia Guintini, Audrey Paillé, Marco Graf, Brian Luke, Raymund J Wellinger, Antonio Conconi
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010167 (2022)
Ultraviolet light causes DNA lesions that are removed by nucleotide excision repair (NER). The efficiency of NER is conditional to transcription and chromatin structure. UV induced photoproducts are repaired faster in the gene transcribed strands tha
Externí odkaz:
https://doaj.org/article/d356cfd42acf4603a46d51ecc0eb0c6f
Autor:
Emeline Pasquier, Raymund J. Wellinger
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-22 (2020)
Abstract Background DNA packaging into chromatin regulates all DNA-related processes and at chromosomal ends could affect both essential functions of telomeres: protection against DNA damage response and telomere replication. Despite this primordial
Externí odkaz:
https://doaj.org/article/2a24c716aefd40408fb5fa11146f8ad8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Eukaryotic genomes are highly complex and divided into linear chromosomes that require end protection from unwarranted fusions, recombination, and degradation in order to maintain genomic stability. This is accomplished through the conserved speciali
Externí odkaz:
https://doaj.org/article/a1807565c9204f72bea32915365a5bc5
Publikováno v:
eLife, Vol 9 (2020)
The templating RNA is the core of the telomerase reverse transcriptase. In Saccharomyces cerevisiae, the complex life cycle and maturation of telomerase includes a cytoplasmic stage. However, timing and reason for this cytoplasmic passage are poorly
Externí odkaz:
https://doaj.org/article/4db8eee621c1422e874ab53abd8376c7
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008733 (2020)
In budding yeast, Cdc13, Stn1, and Ten1 form the telomere-binding heterotrimer CST complex. Here we investigate the role of Cdc13/CST in maintaining genome stability by using a Chr VII disome system that can generate recombinants, chromosome loss, an
Externí odkaz:
https://doaj.org/article/086e256930e04d55be311ba70fa6f846
Autor:
Hannah Neumann, Celia Jeronimo, Jean-François Lucier, Emeline Pasquier, François Robert, Raymund J. Wellinger, Luc Gaudreau
Publikováno v:
Microbiology Spectrum. 11
We provide evidence that the Saccharomyces cerevisiae C-terminal region of histone variant H2A.Z can mediate its special function in performing gene regulation by interacting with effector proteins and chaperones. These functional interactions allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1c339f45dcb773e8ec6737aedadb2b
https://doi.org/10.1128/spectrum.02550-22
https://doi.org/10.1128/spectrum.02550-22
Autor:
Sherif Abou Elela, Claudine Rancourt, Benoit Chabot, Raymund J. Wellinger, Panagiotis Prinos, Karine Tremblay, Jean-Francois Lucier, Philippe Thibault, Jean-Philippe Brosseau, Daniel Gendron, Mathieu Durand, Ulrike Froehlich, Elvy Lapointe, Julien Gervais-Bird, ChuShin Koh, Geneviève Dufresne-Martin, Lyna Inkel, Anne Bramard, Roscoe Klinck, Julian P. Venables
Interactive data link from Identification of Alternative Splicing Markers for Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3f34abb3392cdeef6025b133e796e9
https://doi.org/10.1158/0008-5472.22376541.v1
https://doi.org/10.1158/0008-5472.22376541.v1
Autor:
Sherif Abou Elela, Claudine Rancourt, Benoit Chabot, Raymund J. Wellinger, Panagiotis Prinos, Karine Tremblay, Jean-Francois Lucier, Philippe Thibault, Jean-Philippe Brosseau, Daniel Gendron, Mathieu Durand, Ulrike Froehlich, Elvy Lapointe, Julien Gervais-Bird, ChuShin Koh, Geneviève Dufresne-Martin, Lyna Inkel, Anne Bramard, Roscoe Klinck, Julian P. Venables
Supplementary Figure 9 from Identification of Alternative Splicing Markers for Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cf277d9b85a484ce04d51058ac0008
https://doi.org/10.1158/0008-5472.22376529
https://doi.org/10.1158/0008-5472.22376529