Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials

Autor: Richard Gray, Rosie Bradley, Jeremy Braybrooke, Zulian Liu, Richard Peto, Lucy Davies, David Dodwell, Paul McGale, Hongchao Pan, Carolyn Taylor, William Barlow, Judith Bliss, Paolo Bruzzi, David Cameron, George Fountzilas, Sibylle Loibl, John Mackey, Miguel Martin, Lucia Del Mastro, Volker Möbus, Valentina Nekljudova, Sabino De Placido, Sandra Swain, Michael Untch, Kathleen I Pritchard, Jonas Bergh, Larry Norton, Clare Boddington, Julie Burrett, Mike Clarke, Christina Davies, Fran Duane, Vaughan Evans, Lucy Gettins, Jon Godwin, Robert Hills, Sam James, Hui Liu, Elizabeth MacKinnon, Gurdeep Mannu, Theresa McHugh, Philip Morris, Simon Read, Yaochen Wang, Zhe Wang, Peter Fasching, Nadia Harbeck, Pascal Piedbois, Michael Gnant, Guenther Steger, Angelo Di Leo, Stella Dolci, Prue Francis, Denis Larsimont, Jean Marie Nogaret, Catherine Philippson, Martine Piccart, Sabine Linn, Petronella Peer, Vivianne Tjan-Heijnen, Sonja Vliek, Dennis Slamon, John Bartlett, Vivien H Bramwell, Bingshu Chen, Stephen Chia, Karen Gelmon, Paul Goss, Mark Levine, Wendy Parulekar, Joseph Pater, Eileen Rakovitch, Lois Shepherd, Dongsheng Tu, Tim Whelan, Don Berry, Gloria Broadwater, Constance Cirrincione, Hyman Muss, Raymond Weiss, Yi Shan, Yong Fu Shao, Xiang Wang, Binghe Xu, Dong-Bing Zhao, Harry Bartelink, Nina Bijker, Jan Bogaerts, Fatima Cardoso, Tanja Cufer, Jean-Pierre Julien, Philip Poortmans, Emiel Rutgers, Cornelis van de Velde, Eva Carrasco, Miguel Angel Segui, Jens Uwe Blohmer, Serban Costa, Bernd Gerber, Christian Jackisch, Gunter von Minckwitz, Mario Giuliano, Michele De Laurentiis, Christina Bamia, Georgia-Angeliki Koliou, Dimitris Mavroudis, Roger A'Hern, Paul Ellis, Lucy Kilburn, James Morden, John Yarnold, Mohammad Sadoon, Augustinus H Tulusan, Stewart Anderson, Gordon Bass, Joe Costantino, James Dignam, Bernard Fisher, Charles Geyer, Eleftherios P Mamounas, Soon Paik, Carol Redmond, D Lawrence Wickerham, Marco Venturini, Claudia Bighin, Simona Pastorino, Paolo Pronzato, Mario Roberto Sertoli, Theodorus Foukakis, Kathy Albain, Rodrigo Arriagada, Elizabeth Bergsten Nordström, Francesco Boccardo, Etienne Brain, Lisa Carey, Alan Coates, Robert Coleman, Candace Correa, Jack Cuzick, Nancy Davidson, Mitch Dowsett, Marianne Ewertz, John Forbes, Richard Gelber, Aron Goldhirsch, Pamela Goodwin, Daniel Hayes, Catherine Hill, James Ingle, Reshma Jagsi, Wolfgang Janni, Hirofumi Mukai, Yasuo Ohashi, Lori Pierce, Vinod Raina, Peter Ravdin, Daniel Rea, Meredith Regan, John Robertson, Joseph Sparano, Andrew Tutt, Giuseppe Viale, Nicholas Wilcken, Norman Wolmark, Wiliam Wood, Milvia Zambetti

Publikováno v: The Lancet, vol. 393, no. 10179, pp. 1440-1452, 2019.
Cameron, D 2019, ' Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient level meta-analysis of 37,298 women with early breast cancer in 26 randomised trials ', The Lancet . https://doi.org/10.1016/S0140-6736(18)33137-4

Background Increasing the dose intensity of cytotoxic therapy by shortening the intervals between cycles, or by giving individual drugs sequentially at full dose rather than in lower-dose concurrent treatment schedules, might enhance efficacy. Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aaeb033807be6d203ebd5f4b088a46
https://doi.org/10.1016/s0140-6736(18)33137-4

Cryosurgical posterior nasal tissue ablation for the treatment of rhinitis

Autor: Peter H, Hwang, Bryant, Lin, Raymond, Weiss, James, Atkins, Jacob, Johnson

Publikováno v: International Forum of Allergy & Rhinology

Background Endoscopic posterior nasal nerve (PNN) resection has been described as an efficacious surgical treatment of allergic and nonallergic rhinitis, but the requirement for surgery under general anesthesia has limited its acceptance. We report t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9a2f28a066a81469865428ad48d496f
https://pubmed.ncbi.nlm.nih.gov/28799727

Structure and mixed spin state of the chloroiron(III) complex of 2,3,7,8,12,13,17,18-octaphenyl-5,10,15,20-tetraphenylporphyrin, Fe(dpp)Cl

Autor: Michael Gerdan, Alain Tabard, Alfred X. Trautwein, Volker Schünemann, Roger Guilard, Jean Fischer, Véronique Bulach, Raymond Weiss, Claude P. Gros, John A. Shelnutt

Publikováno v: Inorganica Chimica Acta. 337:223-232

The chloroiron(III) complex Fe(dpp)Cl (1) of the peripherally crowded 2,3,7,8,12,13,17,18-octaphenyl-5,10,15,20-tetraphenylporphyrin or dodecaphenylporphyrin (dpp), has been synthesized and characterized by X-ray crystallography, normal-coordinate st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f24db6f78a1d26be32ee2b761be5a34d
https://doi.org/10.1016/s0020-1693(02)01087-3

Valence-tautomerism in high-valent iron and manganese porphyrins

Autor: Avram Gold, Alfred X. Trautwein, James Terner, Véronique Bulach, Raymond Weiss

Publikováno v: JBIC Journal of Biological Inorganic Chemistry. 6:831-845

Iron and manganese hemes are "high-valent" when the valence state of the metal exceeds III. Redox chemistry of the high valent metal complexes involves redistribution of holes and electrons over the metal ion and the porphyrin and axial ligands, defi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c0e3ff0a051d13f56c0cc561ad75e9
https://doi.org/10.1007/s007750100277

Alkyl and Aryl Substituted Corroles. 2. Synthesis and Characterization of Linked 'Face-to-Face' Biscorroles. X-ray Structure of (BCA)Co2(py)3, Where BCA Represents a Biscorrole with an Anthracenyl Bridge

Autor: Jean Fischer, Raymond Weiss, Jean-Michel Barbe, Jianguo Shao, Zhongping Ou, Karl M. Kadish, Roger Guilard, François Jérôme, Claude P. Gros

Publikováno v: Inorganic Chemistry. 40:4856-4865

The synthesis, spectroscopic properties, and electrochemistry of (BCA)Co(2) and (BCB)Co(2) are described where BCA and BCB represent biscorroles linked by an anthracenyl (A) or a biphenylenyl (B) bridge. The pyridine and CO binding properties of (BCA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33a9a106a4a58045adb9e2a21be3c88
https://doi.org/10.1021/ic0101782