Zobrazeno 1 - 10
of 723
pro vyhledávání: '"Raymond W. Lam"'
Autor:
Benjamin Schwartzmann, Raaj Chatterjee, Yasaman Vaghei, Lena C. Quilty, Timothy A. Allen, Stephen R. Arnott, Sravya Atluri, Pierre Blier, Prabhjot Dhami, Jane A. Foster, Benicio N. Frey, Stefan Kloiber, Raymond W. Lam, Roumen Milev, Daniel J. Müller, Claudio N. Soares, Chloe Stengel, Sagar V. Parikh, Gustavo Turecki, Rudolf Uher, Susan Rotzinger, Sidney H. Kennedy, Faranak Farzan
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Current pharmacological agents for depression have limited efficacy in achieving remission. Developing and validating new medications is challenging due to limited biological targets. This study aimed to link electrophysiological data and sy
Externí odkaz:
https://doaj.org/article/dc3afdb50ff84053bc8645b81ace4153
Autor:
Raegan Mazurka, Kate L. Harkness, Stefanie Hassel, Niclas Stensson, Nikita Nogovitsyn, Jordan Poppenk, Jane A. Foster, Scott D. Squires, Jessie Rowe, Roumen V. Milev, Katherine E. Wynne-Edwards, Gustavo Turecki, Stephen C. Strother, Stephen R. Arnott, Raymond W. Lam, Susan Rotzinger, Sidney H. Kennedy, Benicio N. Frey, Leah M. Mayo
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Evidence from preclinical animal models suggests that the stress-buffering function of the endocannabinoid (eCB) system may help protect against stress-related reductions in hippocampal volume, as is documented in major depressive disorder (
Externí odkaz:
https://doaj.org/article/917343a666d64cd1a4adf3f4eb45afc6
Autor:
Sondos Ayyash, Andrew D. Davis, Gésine L. Alders, Glenda MacQueen, Stephen C. Strother, Stefanie Hassel, Mojdeh Zamyadi, Stephen R. Arnott, Jacqueline K. Harris, Raymond W. Lam, Roumen Milev, Daniel J. Müller, Sidney H. Kennedy, Susan Rotzinger, Benicio N. Frey, Luciano Minuzzi, Geoffrey B. Hall
Publikováno v:
IBRO Neuroscience Reports, Vol 16, Iss , Pp 135-146 (2024)
Neural network-level changes underlying symptom remission in major depressive disorder (MDD) are often studied from a single perspective. Multimodal approaches to assess neuropsychiatric disorders are evolving, as they offer richer information about
Externí odkaz:
https://doaj.org/article/771e6395e0174ac6abab9d6595cdd966
Autor:
Srinivasan Vairavan, Homa Rashidisabet, Qingqin S. Li, Seth Ness, Randall L. Morrison, Claudio N. Soares, Rudolf Uher, Benicio N. Frey, Raymond W. Lam, Sidney H. Kennedy, Madhukar Trivedi, Wayne C. Drevets, Vaibhav A. Narayan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Major depressive disorder (MDD) is a chronic illness wherein relapses contribute to significant patient morbidity and mortality. Near-term prediction of relapses in MDD patients has the potential to improve outcomes by helping implement a
Externí odkaz:
https://doaj.org/article/87bfe25f79a54057abdc226ad6b90aeb
Autor:
Anastasiya Slyepchenko, Rudolf Uher, Keith Ho, Stefanie Hassel, Craig Matthews, Patricia K. Lukus, Alexander R. Daros, Anna Minarik, Franca Placenza, Qingqin S. Li, Susan Rotzinger, Sagar V. Parikh, Jane A. Foster, Gustavo Turecki, Daniel J. Müller, Valerie H. Taylor, Lena C. Quilty, Roumen Milev, Claudio N. Soares, Sidney H. Kennedy, Raymond W. Lam, Benicio N. Frey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Monitoring sleep and activity through wearable devices such as wrist-worn actigraphs has the potential for long-term measurement in the individual’s own environment. Long periods of data collection require a complex approach, including sta
Externí odkaz:
https://doaj.org/article/a693500a0bcd42ea8003426e263478cf
Autor:
Sophie R. Vaccarino, Shijing Wang, Sakina J. Rizvi, Wendy Lou, Stefanie Hassel, Glenda M. MacQueen, Keith Ho, Benicio N. Frey, Raymond W. Lam, Roumen V. Milev, Susan Rotzinger, Arun V. Ravindran, Stephen C. Strother, Sidney H. Kennedy
Publikováno v:
BJPsych Open, Vol 10 (2024)
Background Identifying neuroimaging biomarkers of antidepressant response may help guide treatment decisions and advance precision medicine. Aims To examine the relationship between anhedonia and functional neurocircuitry in key reward processing br
Externí odkaz:
https://doaj.org/article/77d2fe07dfd042d58f24c25fd21fe5e1
Autor:
Benjamin Schwartzmann, Lena C. Quilty, Prabhjot Dhami, Rudolf Uher, Timothy A. Allen, Stefan Kloiber, Raymond W. Lam, Benicio N. Frey, Roumen Milev, Daniel J. Müller, Claudio N. Soares, Jane A. Foster, Susan Rotzinger, Sidney H. Kennedy, Faranak Farzan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Cognitive behavioral therapy (CBT) is often recommended as a first-line treatment in depression. However, access to CBT remains limited, and up to 50% of patients do not benefit from this therapy. Identifying biomarkers that can predict whic
Externí odkaz:
https://doaj.org/article/40d35cf6aa3e4b00bfc2b664c56cefa4
Autor:
Farhana Islam, Victoria S. Marshe, Leen Magarbeh, Benicio N. Frey, Roumen V. Milev, Claudio N. Soares, Sagar V. Parikh, Franca Placenza, Stephen C. Strother, Stefanie Hassel, Valerie H. Taylor, Francesco Leri, Pierre Blier, Rudolf Uher, Faranak Farzan, Raymond W. Lam, Gustavo Turecki, Jane A. Foster, Susan Rotzinger, Sidney H. Kennedy, Daniel J. Müller
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cytochrome P450 drug-metabolizing enzymes may contribute to interindividual differences in antidepressant outcomes. We investigated the effects of CYP2C19 and CYP2D6 gene variants on response, tolerability, and serum concentrations. Patients
Externí odkaz:
https://doaj.org/article/9778a0edbdd84368b4e3259ab8be4b8e
Autor:
Anthony L. Vaccarino, Sandra E. Black, Susan Gilbert Evans, Benicio N. Frey, Mojib Javadi, Sidney H. Kennedy, Benjamin Lam, Raymond W. Lam, Bianca Lasalandra, Emily Martens, Mario Masellis, Roumen Milev, Sara Mitchell, Douglas P. Munoz, Alana Sparks, Richard H. Swartz, Brian Tan, Rudolf Uher, Kenneth R. Evans
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundSymptoms of depression are present in neurodegenerative disorders (ND). It is important that depression-related symptoms be adequately screened and monitored in persons living with ND. The Quick Inventory of Depressive Symptomatology Self-R
Externí odkaz:
https://doaj.org/article/556fd155cd56471984fae95b0daaffbb
Autor:
Raymond W. Lam, Hee-Kit Wong, Ramruttun A. Kumarsing, Anna N. Chua, Roger C. Ho, Roger S. McIntyre, Cyrus S. Ho
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Depression is one of the most prevalent mental disorders associated with reductions in bone mineral density and increased fracture risk. Fluoxetine is a highly prescribed selective serotonin reuptake inhibitor (SSRI) in the treatment of depr
Externí odkaz:
https://doaj.org/article/cd4059bb52a441e9a9a5667d23935dfa