Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Raymond Taetle"'
Autor:
Roger M. Lyons, Yunfei Wang, Philip Y. Dien, Nicholas J. Di Bella, Robert N. Raju, Julie Boston, Kathryn S. Kolibaba, Svetislava J. Vukelja, David Barrera, Raymond Taetle, Peter J. Schlegel, Thomas E. Boyd, Lina Asmar, Kristi A. Boehm, Ernest W. Cochran
Publikováno v:
Blood. 115:475-480
This study evaluated the efficacy and safety of single-agent bortezomib in indolent B-cell lymphoma that had relapsed from or was refractory to rituximab. Sixty patients enrolled: 59 were treated with bortezomib 1.3 mg/m2 on days 1, 4, 8, and 11 for
Autor:
Raymond Taetle, Mikel Aickin
Publikováno v:
Cancer Genetics and Cytogenetics. 166:22-26
Biological processes are often accompanied by occurrences of multiple events, such as activation of certain cell types, change in prevalence of cell subpopulations (such as T cells), changes in concentration of proteins or peptides, or breaks in chro
Autor:
Mark A. Nelson, Raymond Taetle, Richard M. Simon, Alejandro A. Schäffer, Michael D. Radmacher, Richard Desper
Publikováno v:
Journal of Theoretical Biology. 212:535-548
We describe several analytical techniques for use in developing genetic models of oncogenesis including: methods for the selection of important genetic events, construction of graph models (including distance-based trees, branching trees, contingency
Autor:
FH Thompson, Stanley P. L. Leong, Mikel Aickin, Jerry L. Bangert, Mark A. Nelson, Michael D. Radmacher, Raymond Taetle, Lawrence Adair, Jeffrey M. Trent, Sydney E. Salmon, Lita Panda, Jin Ming Yang, Denise J. Roe, Richard Simon, Julia Emerson
Publikováno v:
Cancer Genetics and Cytogenetics. 122:101-109
We report the cytogenetic abnormalities from a series of 206 primary malignant melanoma specimens referred to a single institution. A total of 169 out of 206 unique cases had chromosome breakpoints. A previously described statistical method was used
Autor:
Amy C. Peng, Richard Simon, Jeffrey M. Trent, Raymond Taetle, Richard Desper, Alejandro A. Schäffer, David S. Alberts, Christos H. Papadimitriou
Publikováno v:
Genes, Chromosomes and Cancer. 28:106-120
Cancer geneticists seek to identify genetic changes in tumor cells and to relate the genetic changes to tumor development. Because single changes can disrupt the cell cycle and promote other genetic changes, it is extremely hard to distinguish cause
Frequent Alterations of Evolutionarily Conserved Regions of Chromosome 1 in Human Malignant Melanoma
Publikováno v:
Cancer Genetics and Cytogenetics. 111:119-123
Recurring alterations of chromosome 1 represent the most frequent site of structural chromosome abnormalities across all human solid tumors, including human cutaneous malignant melanoma. In melanoma, breakpoints involving chromosome 1 appear to accum
Autor:
Denise J. Roe, Raymond Taetle, FH Thompson, John R. Davis, Jeffrey M. Trent, David S. Alberts, Lita Panda, Julia Emerson, Mikel Aickin
Publikováno v:
Genes, Chromosomes and Cancer. 25:46-52
In a large series of ovarian carcinomas from 244 patients, 134 cases had chromosome rearrangements. We showed before that the pattern of chromosome breakpoints involved 21 separate chromosome regions nonrandomly and, in 90% of cases with breaks, the
Autor:
Raymond Taetle, Marianne Broome-Powell, Jin Ming Yang, FH Thompson, Maria E. Ariza, Mark A. Nelson, Julie Wymer, Jeffrey M. Trent, Vincent J. Kidd, Kathy Massey-Brown, Jill M. Lahti, John Easton
Publikováno v:
Cancer Genetics and Cytogenetics. 108:91-99
The two genes encoding the PITSLRE protein kinase isoforms, CDC2L1 and CDC2L2, are localized to human chromosome band 1p36. The PITSLRE protein kinases are a part of the p34cdc2 supergene family. Several protein products of the CDC2L locus may be eff
Publikováno v:
Leukemia Research. 23:77-83
Twenty-two patients with myelodysplastic syndrome were treated with combined recombinant human erythropoietin and recombinant human interleukin 3 (rHuIL-3). All 22 patients were evaluable for toxicity and 21/22 for response. Thirteen patients (62%) r
Autor:
Hongen Zhang, Xin Yuan Guan, Raymond Taetle, Jeffrey M. Trent, Jin Ming Yang, Paul S. Meltzer, Jane Wang
Publikováno v:
Cancer Genetics and Cytogenetics. 107:89-92
Chromosome 6 abnormalities, particularly the deletion of 6q, are among the most frequent chromosomal changes in human malignant melanoma. In this study, chromosome 6 rearrangements in 21 melanoma cell lines were identified by fluorescence in situ hyb