Výsledky vyhledávání - "Raymond T. Jones"

Reproductive and hormonal factors and the risk of nonsmall cell lung cancer

Autor: Elise D. Bowman, James V. Lacey, Donna Perlmutter, Amy Berrington de Gonzalez, Alina V. Brenner, Raymond T. Jones, Sara J. Schonfeld, Curtis C. Harris, Christopher A. Loffredo, G. E. Trivers, Cari L. Meinhold

Publikováno v: International Journal of Cancer. 128:1404-1413

Although exposure to estrogen may directly influence or modify the association between cigarette smoking and lung cancer risk, results from epidemiologic studies examining the association between reproductive and hormonal factors and risk of lung can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4d28604028e19d5fe30b1a026ce15b
https://doi.org/10.1002/ijc.25434

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Less Efficient G2-M Checkpoint Is Associated with an Increased Risk of Lung Cancer in African Americans

Autor: Lindsey Enewold, Rex C. Yung, Raymond T. Jones, Anthony J. Alberg, Donna Perlmutter, Zhipeng Yu, Mark J. Krasna, Peter G. Shields, Curtis C. Harris, Christopher A. Loffredo, Yun Ling Zheng

Publikováno v: Cancer Research. 65:9566-9573

Cell cycle checkpoints play critical roles in the maintenance of genomic integrity. The inactivation of checkpoint genes by genetic and epigenetic mechanisms is frequent in all cancer types, as a less-efficient cell cycle control can lead to genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6876aea24e07ea77161bafa30fe4c9a0
https://doi.org/10.1158/0008-5472.can-05-1003

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Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls

Autor: Peter G. Shields, Anthony J. Alberg, Rex C. Yung, Zhipeng Yu, Yun Ling Zheng, Lindsey Enewold, Raymond T. Jones, Donna Perlmutter, Mark J. Krasna, Curtis C. Harris, Christopher A. Loffredo

Publikováno v: Carcinogenesis. 24:269-274

Environmental exposure to carcinogens and individual susceptibility play significant roles in cancer risk. Suboptimal DNA repair capability, measured by quantifying mutagen-induced chromosome breaks, might explain variable host susceptibility to envi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0441ded1aebc2b1858985c3290122674
https://doi.org/10.1093/carcin/24.2.269

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Quantitative Image Analysis of p53 Protein Accumulation in Keratoacanthomas

Autor: William P. Bennett, Piotr Borkowski, Grace F. Kao, Curtis C. Harris, Andrzej Borkowski, Raymond T. Jones, Benjamin F. Trump, Luciano R. Ferreira

Publikováno v: The American Journal of Dermatopathology. 17:335-338

Keratoacanthomas are benign skin tumors that grow rapidly but eventually regress. They occur most commonly in sun-exposed skin and are histologically remarkably similar to squamous cancers. Since mutations of the p53 tumor suppressor gene are found f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e507232dee3275deefcd77b2053f07c0
https://doi.org/10.1097/00000372-199508000-00005

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Effects of chronic copper exposure on the macrophage chemiluminescent response and gill histology in goldfish (Carassius auratusL.)

Autor: Ann G Muhvich, Andrew S. Kane, Raymond T. Jones, Renate Reimscheussel, Robert S. Anderson

Publikováno v: Fish & Shellfish Immunology. 5:251-264

The effects of chronic copper exposure on the macrophage chemiluminescent response and gill histology in goldfish ( Carassius auratus L.) were determined. Fish were exposed to sublethal concentrations (30, 65, 100, and 175 ppb) of copper sulphate for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7d649c1c6f225be9cf29610679df7a2
https://doi.org/10.1006/fsim.1995.0025

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Studies of human bronchial epithelium in vitro: Changes of [Ca(2+)](i) in relation to injury, growth and differentiation

Autor: M. Miyashita, Irene K. Berezesky, Raymond T. Jones, Mary W. Smith, Benjamin F. Trump, C. C. Harris, P. C. Phelps

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 4(4-5)

The objectives of the present work included the study of the response of normal human bronchial epithelial (NHBE) cells to injury following treatment with several agents, especially those associated with tumour promotion. The effects of putative tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2717288083880cc5ac5be3fcc8c2b32
https://pubmed.ncbi.nlm.nih.gov/20702249

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Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study

Autor: Ourania Kosti, Peter G. Shields, Raymond T. Jones, Elise D. Bowman, Yun-Ling Zheng, Donna Perlmutter, Leah E. Mechanic, Curtis C. Harris, Christopher A. Loffredo

Publikováno v: International Journal of Cancer.

Cell cycle checkpoints play critical roles in the maintenance of genomic integrity and inactivation of checkpoint genes are frequently perturbed in most cancers. In a case-control study of 299 non-small cell lung cancer cases and 550 controls in Balt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e674000f7d81aa9eefb6b41c8f656f9
https://doi.org/10.1002/ijc.24771

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Regulation of protein degradation in normal and transformed human bronchial epithelial cells in culture

Autor: L Marzella, Roy A.M. Myers, Hsiang-Kuang Lee, Raymond T. Jones

Publikováno v: Archives of Biochemistry and Biophysics. 296:271-278

Protein degradation rates are decreased in some transformed cells of mesenchymal origin. We have tested the generality of this phenomenon and evaluated the role of the lysosomes in this down-regulation. To this end we have compared the induction of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89634ad21644a15d9cbda89ce2a67ee
https://doi.org/10.1016/0003-9861(92)90572-e

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Cell-to-cell communication: a differential response to TGF-β in normal and transformed (BEAS-2B) human bronchial epithelial cells

Autor: Philip M. Grimley, Craig D. Albright, Joseph A. Fontana, Raymond T. Jones, Kevin P. Keenan, James H. Resau

Publikováno v: Carcinogenesis. 12:1993-1999

The effects of transforming growth factor beta (TGF-beta) on cell-to-cell communication were investigated in the log phase of growth in normal BE and in adenovirus-12 SV40 hybrid virus transformed BE cells (strain BEAS-2B). Gap junctions in these cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6978a089aa6836bd88d84b660819b859
https://doi.org/10.1093/carcin/12.11.1993

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