Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Raymond T Syvitski"'
Autor:
Chris V Bowen, Drew DeBay, H Stephen Ewart, Pamela Gallant, Sean Gormley, T Toney Ilenchuk, Umar Iqbal, Tyler Lutes, Marzia Martina, Geoffrey Mealing, Nadine Merkley, Sandra Sperker, Maria J Moreno, Christopher Rice, Raymond T Syvitski, John M Stewart
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58866 (2013)
Soricidin is a 54-amino acid peptide found in the paralytic venom of the northern short-tailed shrew (Blarina brevicauda) and has been found to inhibit the transient receptor potential of vallinoid type 6 (TRPV6) calcium channels. We report that two
Externí odkaz:
https://doaj.org/article/35c52c9afae442ebb022516fdad112ea
Publikováno v:
Biochemistry and Cell Biology. 95:295-303
The phospho-transfer mechanism of yeast phosphoglycerate kinase (PGK) has been probed through formation of trifluoromagnesate (MgF3−) and tetrafluoroaluminate (AlF4−) transition state analogue complexes and analyzed using19F,1H waterLOGSY and1H c
Autor:
Raymond T. Syvitski, Camilo F. Martinez-Farina, Stephanie M. Forget, Andrew W. Robertson, Nicole E. McCormick, David L. Jakeman
Publikováno v:
Journal of the American Chemical Society. 138:2200-2208
We report that JadX, a protein of previously undetermined function coded for in the jadomycin biosynthetic gene cluster of Streptomyces venezuelae ISP5230, affects both chloramphenicol and jadomycin production levels in blocked mutants. Characterizat
Autor:
Raymond T. Syvitski, Camilo F. Martinez-Farina, Huimin Yin, Susan Monro, David L. Jakeman, Sherri A. McFarland, Andrew W. Robertson
Publikováno v:
Journal of Natural Products. 78:1208-1214
Streptomyces venezuelae ISP5230 was grown in the presence of phenylalanine analogues to observe whether they could be incorporated into novel jadomycin structures. It was found that the bacteria successfully produced jadomycins incorporating 4-aminop
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 95(2)
The phospho-transfer mechanism of yeast phosphoglycerate kinase (PGK) has been probed through formation of trifluoromagnesate (MgF
Autor:
Susan E. Douglas, Junni Mai, Yung-Hua Li, Nadine Merkley, Zakia Biswas, Jeffrey W. Gallant, Raymond T. Syvitski, Junqi Ling, Xiao-Lin Tian
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:5205-5213
In this study, we constructed and evaluated a target-specific, salt-resistant antimicrobial peptide (AMP) that selectively targeted Streptococcus mutans , a leading cariogenic pathogen. The rationale for creating such a peptide was based on the addit
Autor:
B. Srinivasulu, Neil R. Mattatall, L. C. Knickle, Jung-Kil Seo, Raymond T. Syvitski, Susan E. Douglas
Publikováno v:
Protein Expression and Purification. 61:36-44
The cysteine-rich peptide hepcidin is an antimicrobial peptide and iron transport regulator that has been found in vertebrates including birds, fish and mammals. To elucidate the structure and biological function of fish hepcidin, which is difficult
Autor:
Raymond T. Syvitski, Song F. Lee, Kamal Sampara, Yung-Hua Li, Alan Salman, Xiao-Lin Tian, David L. Jakeman
Publikováno v:
Journal of Bacteriology. 189:1441-1450
Streptococcus mutans secretes and utilizes a 21-amino-acid signaling peptide pheromone to initiate quorum sensing for genetic competence, biofilm formation, stress responses, and bacteriocin production. In this study, we designed and synthesized a se
Publikováno v:
Journal of natural products. 78(8)
The jadomycin-derived compound l-digitoxosyl-phenanthroviridin was isolated from fermentations of Streptomyces venezuelae ISP5230 grown in nutrient-deficient media with l-lysine as the sole nitrogen source. Structural elucidation was accomplished usi
Autor:
Andrew W. Robertson, Susan Monro, Sherri A. McFarland, Raymond T. Syvitski, Camilo F. Martinez-Farina, Huimin Yin, David L. Jakeman, Alison Thompson, Deborah A. Smithen
Publikováno v:
Journal of the American Chemical Society. 137(9)
Jadomycin Oct (1) was isolated from Streptomyces venezuelae ISP5230 and characterized as a structurally unique eight-membered l-ornithine ring-containing jadomycin. The structure was elucidated through the semisynthetic derivatization of starting mat