Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Raymond T Suhandynata"'
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247132 (2021)
Protein sumoylation, especially when catalyzed by the Mms21 SUMO E3 ligase, plays a major role in suppressing duplication-mediated gross chromosomal rearrangements (dGCRs). How Mms21 targets its substrates in the cell is insufficiently understood. He
Externí odkaz:
https://doaj.org/article/9063ef024c61476284d1e4cc3e78d021
Autor:
Raymond T Suhandynata, Yun Quan, Yusheng Yang, Wei-Tsung Yuan, Claudio P Albuquerque, Huilin Zhou
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008477 (2019)
The kinetochore is the central molecular machine that drives chromosome segregation in all eukaryotes. Genetic studies have suggested that protein sumoylation plays a role in regulating the inner kinetochore; however, the mechanism remains elusive. H
Externí odkaz:
https://doaj.org/article/b4d8cdfd98514d7cafa4e1e71631908b
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155931 (2016)
Meiotic recombination plays a key role in sexual reproduction as it generates crossovers that, in combination with sister chromatid cohesion, physically connect homologous chromosomes, thereby promoting their proper segregation at the first meiotic d
Externí odkaz:
https://doaj.org/article/590983cf13ec49fda480b37ef319df30
Autor:
Marlen Menlyadiev, Raymond T. Suhandynata, Kyle Lund, Michael J. Kelner, Robert L. Fitzgerald
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 28, Iss , Pp 105-113 (2023)
Introduction: While laboratory-developed tests (LDTs) using liquid chromatography tandem mass spectrometry (LC-MS/MS) are widely employed to support the development of FDA-cleared drug immunoassays, their significance in the clinical implementation a
Externí odkaz:
https://doaj.org/article/267ef71f9af64947b9fcdff71988ee5c
Autor:
Kyle Lund, Marlen Menlyadiev, Kyunghoon Lee, Michael J. Kelner, Robert L. Fitzgerald, Raymond T. Suhandynata
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 28, Iss , Pp 91-98 (2023)
Background: The VALID Act is a legislative effort that, if enacted, would alter the regulatory requirements of laboratory developed tests (LDTs) used for clinical testing in the United States. Benzodiazepines, which are primarily excreted into urine
Externí odkaz:
https://doaj.org/article/6ccd9e7fe693441ab3323710600f0623
Autor:
Robert L Fitzgerald, Anya Umlauf, Jacqueline A Hubbard, Melissa A Hoffman, Philip M Sobolesky, Shannon E Ellis, David J Grelotti, Raymond T Suhandynata, Marilyn A Huestis, Igor Grant, Thomas D Marcotte
Publikováno v:
Clinical Chemistry.
Background Cannabis is increasingly used both medically and recreationally. With widespread use, there is growing concern about how to identify cannabis-impaired drivers. Methods A placebo-controlled randomized double-blinded protocol was conducted t
Autor:
Marlon Liyanage, Mina Nikanjam, Edmund V. Capparelli, Raymond T. Suhandynata, Robert L. Fitzgerald, Thomas D. Marcotte, Igor Grant, Jeremiah D. Momper
Publikováno v:
Therapeutic Drug Monitoring.
Autor:
Jehad Almaliti, Pavla Fajtová, Jaeson Calla, Gregory M. LaMonte, Mudong Feng, Frances Rocamora, Sabine Ottilie, Evgenia Glukhov, Evzen Boura, Raymond T. Suhandynata, Jeremiah D. Momper, Michael K. Gilson, Elizabeth A. Winzeler, William H. Gerwick, Anthony J. O'Donoghue
Here we present remarkable epoxyketone-based proteasome inhibitors with low nanomolar in vitro potency for blood-stage Plasmodium falciparum and low cytotoxicity for human cells. Our best compound has more than 2,000-fold greater selectivity for eryt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::b8eb6ef78093603656917035ab9eee71
https://zenodo.org/record/7655290
https://zenodo.org/record/7655290
Autor:
Amadeo, Pesce, Raymond T, Suhandynata, Dennis, Ritz, Richard, Thomas, Gregory, Ackerman, Katie, Bollman
Publikováno v:
Annals of clinical and laboratory science. 52(6)
The conjunction of the coronavirus disease lockdown and the use of illicit drugs suggests the potential increase in drug usage and opioid deaths. Because of other studies, we felt the need to examine if the lockdown has caused a change in the drug in
Autor:
Raymond T. Suhandynata, Kyle Lund, Nicholas J Bevins, Andrés Mauricio Caraballo-Rodríguez, Sharon L. Reed, Robert L. Fitzgerald, Pieter C. Dorrestein
Publikováno v:
Lab Med
Objective Antibiotic resistance by beta lactamase expression is a serious and growing threat. We aimed to determine whether beta-lactamase activity is detectable in urine specimens to enable faster identification of resistance. Methods Urine specimen