Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Raymond T Ng"'
Autor:
John-Jose Nunez, Teyden T Nguyen, Yihan Zhou, Bo Cao, Raymond T Ng, Jun Chen, Benicio N Frey, Roumen Milev, Daniel J Müller, Susan Rotzinger, Claudio N Soares, Rudolf Uher, Sidney H Kennedy, Raymond W Lam
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253023 (2021)
ObjectivesAntidepressants are first-line treatments for major depressive disorder (MDD), but 40-60% of patients will not respond, hence, predicting response would be a major clinical advance. Machine learning algorithms hold promise to predict treatm
Externí odkaz:
https://doaj.org/article/5d186a23528749dc9f493afd848fde3f
Autor:
David Kepplinger, Mandeep Takhar, Mayu Sasaki, Zsuzsanna Hollander, Derek Smith, Bruce McManus, W Robert McMaster, Raymond T Ng, Gabriela V Cohen Freue
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177569 (2017)
The quantitation of proteins using shotgun proteomics has gained popularity in the last decades, simplifying sample handling procedures, removing extensive protein separation steps and achieving a relatively high throughput readout. The process start
Externí odkaz:
https://doaj.org/article/71bcec8c27484104afa466ea464ed7ac
Autor:
Yu-Wei Roy Chen, Virginia Chen, Zsuzsanna Hollander, Jonathon A Leipsic, Cameron J Hague, Mari L DeMarco, J Mark FitzGerald, Bruce M McManus, Raymond T Ng, Don D Sin
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174063 (2017)
There are currently no accepted and validated blood tests available for diagnosing acute exacerbations of chronic obstructive pulmonary disease (AECOPD). In this study, we sought to determine the discriminatory power of blood C-reactive protein (CRP)
Externí odkaz:
https://doaj.org/article/0cad0b070adc49bd8c38489249bd371c
Autor:
Ihdina Sukma Dewi, Zsuzsanna Hollander, Karen K Lam, Janet-Wilson McManus, Scott J Tebbutt, Raymond T Ng, Paul A Keown, Robert W McMaster, Bruce M McManus, Olof Gidlöf, Jenny Öhman
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170842 (2017)
Identifying non-invasive and reliable blood-derived biomarkers for early detection of acute cellular rejection in heart transplant recipients is of great importance in clinical practice. MicroRNAs are small molecules found to be stable in serum and t
Externí odkaz:
https://doaj.org/article/58e3247693cc40abb5f0f41b72af42b0
Autor:
Janice M Leung, Virginia Chen, Zsuzsanna Hollander, Darlene Dai, Scott J Tebbutt, Shawn D Aaron, Kathy L Vandemheen, Stephen I Rennard, J Mark FitzGerald, Prescott G Woodruff, Stephen C Lazarus, John E Connett, Harvey O Coxson, Bruce Miller, Christoph Borchers, Bruce M McManus, Raymond T Ng, Don D Sin
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161129 (2016)
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) result in considerable morbidity and mortality. However, there are no objective biomarkers to diagnose AECOPD.We used multiple reaction monitoring mass spectrometry to quantify 129
Externí odkaz:
https://doaj.org/article/01437b8b5ec945a5b6af48adf023c0af
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Patients with cancer often have unmet psychosocial needs. Early detection of who requires referral to a counsellor or psychiatrist may improve their care. This work used natural language processing to predict which patients will s
Externí odkaz:
https://doaj.org/article/408df8ba3596426eb5c7af4ee7b47daa
Autor:
Ma'en Obeidat, Nick Fishbane, Yunlong Nie, Virginia Chen, Zsuzsanna Hollander, Scott J Tebbutt, Yohan Bossé, Raymond T Ng, Bruce E Miller, Bruce McManus, Stephen Rennard, Peter D Paré, Don D Sin
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140022 (2015)
BACKGROUND:COPD is currently the fourth leading cause of death worldwide. Statins are lipid lowering agents with documented cardiovascular benefits. Observational studies have shown that statins may have a beneficial role in COPD. The impact of stati
Externí odkaz:
https://doaj.org/article/f5b3a715e81f49a5b3de9c708de72ad8
Autor:
Heesun Shin, Casey P Shannon, Nick Fishbane, Jian Ruan, Mi Zhou, Robert Balshaw, Janet E Wilson-McManus, Raymond T Ng, Bruce M McManus, Scott J Tebbutt, PROOF Centre of Excellence Team
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91041 (2014)
BackgroundThe molecular profile of circulating blood can reflect physiological and pathological events occurring in other tissues and organs of the body and delivers a comprehensive view of the status of the immune system. Blood has been useful in st
Externí odkaz:
https://doaj.org/article/032b41fd10e04d03b8a0503ca4cde6ed
Autor:
Casey P Shannon, Robert Balshaw, Raymond T Ng, Janet E Wilson-McManus, Paul Keown, Robert McMaster, Bruce M McManus, David Landsberg, Nicole M Isbel, Greg Knoll, Scott J Tebbutt
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95224 (2014)
Acute rejection is a major complication of solid organ transplantation that prevents the long-term assimilation of the allograft. Various populations of lymphocytes are principal mediators of this process, infiltrating graft tissues and driving cell-
Externí odkaz:
https://doaj.org/article/f2273797953747e9bc9dbc55318bda33
Autor:
Gabriela V Cohen Freue, Anna Meredith, Derek Smith, Axel Bergman, Mayu Sasaki, Karen K Y Lam, Zsuzsanna Hollander, Nina Opushneva, Mandeep Takhar, David Lin, Janet Wilson-McManus, Robert Balshaw, Paul A Keown, Christoph H Borchers, Bruce McManus, Raymond T Ng, W Robert McMaster, Biomarkers in Transplantation and the NCE CECR Prevention of Organ Failure Centre of Excellence Teams
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 4, p e1002963 (2013)
Recent technical advances in the field of quantitative proteomics have stimulated a large number of biomarker discovery studies of various diseases, providing avenues for new treatments and diagnostics. However, inherent challenges have limited the s
Externí odkaz:
https://doaj.org/article/6bda563f480e4d239955d6a664541f26