Výsledky vyhledávání - "Raymond Steptoe"

Akademický článek

miR-146a inhibits ovarian tumor growth in vivo via targeting immunosuppressive neutrophils and enhancing CD8+ T cell infiltration

Autor: Rui Chen, Elaina Coleborn, Chintan Bhavsar, Yue Wang, Louisa Alim, Andrew N. Wilkinson, Michelle A. Tran, Gowri Irgam, Sharat Atluri, Kiefer Wong, Jae-Jun Shim, Siddharth Adityan, Ju-Seog Lee, Willem W. Overwijk, Raymond Steptoe, Da Yang, Sherry Y. Wu

Publikováno v: Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100725- (2023)

Immunotherapies have emerged as promising strategies for cancer treatment. However, existing immunotherapies have poor activity in high-grade serous ovarian cancer (HGSC) due to the immunosuppressive tumor microenvironment and the associated low tumo

Externí odkaz: https://doaj.org/article/88542394fd9f4c9a9f44ff43addb21fd

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Akademický článek

Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model

Autor: Danielle J. Borg, Pouya Faridi, Kai Lin Giam, Peta Reeves, Amelia K. Fotheringham, Domenica A. McCarthy, Sherman Leung, Micheal S. Ward, Brooke E. Harcourt, Rochelle Ayala, Jean L. Scheijen, David Briskey, Nadine L. Dudek, Casper G. Schalkwijk, Raymond Steptoe, Anthony W. Purcell, Josephine M. Forbes

Publikováno v: Metabolites, Vol 11, Iss 7, p 426 (2021)

Mechanisms by which advanced glycation end products (AGEs) contribute to type 1 diabetes (T1D) pathogenesis are poorly understood. Since life-long pharmacotherapy with alagebrium chloride (ALT) slows progression to experimental T1D, we hypothesized t

Externí odkaz: https://doaj.org/article/aa01d89ace73484cadb792438502955d

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Novel regulators of CD8+ T-cell functions in the skin

Autor: Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L. G., Veitch, Margaret, Frazer, Ian H., Raymond Steptoe, Wells, James W.

Publikováno v: Bridge, J A, Overgaard, N H, Cruz, J L G, Veitch, M, Frazer, I H, Steptoe, R & Wells, J W 2016, ' Novel regulators of CD8+ T-cell functions in the skin ' 10th Asia-Pacific Dermatology Conference, Melbourne, Australia, 28/11/2016-29/11/2016, .
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::22815377252295f011789ce81c7e1115
http://orbit.dtu.dk/en/publications/novel-regulators-of-cd8-tcell-functions-in-the-skin(947f3689-4cc6-4fa9-8090-4d73fe9a313c).html

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Augmentation of dendritic cells in murine organ donors by Flt3 ligand alters the balance between transplant tolerance and immunity

Autor: Raymond Steptoe, Fu, Fm, Li, W., Drakes, Ml, Lu, La, Demetris, Aj, Qian, Sg, Mckenna, Hj, Thomson, Aw

Publikováno v: ResearcherID

Treatment of mice with the recently cloned hemopoietic growth factor Flt3 ligand (FL; 10 microg/day for 10 days) resulted in a large increase in myeloid lineage cells within the liver. While the number of nonparenchymal cells (NPC) harvested from liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559e52bbea9ea0029b22afed7286509b
https://doi.org/10.4049/jimmunol.159.11.5483

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Akademický článek

Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development.

Autor: Meredith O'Keeffe, Thomas C. Brodnicki, Ben Fancke, David Vremec, Grant Morahan, Eugene Maraskovsky, Raymond Steptoe, Leonard C. Harrison, Ken Shortman

Publikováno v: International Immunology; Mar2005, Vol. 17 Issue 3, p307-314, 8p

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IL-1 beta breaks tolerance through expansion of CD25(+) effector T cells

Autor: O Sullivan, Bj, Thomas, He, Pai, S., Santamaria, P., Iwakura, Y., Raymond Steptoe, Kay, Twh, Thomas, R.

Publikováno v: ResearcherID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3bbf378fc7a818f480025d2879783c68
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000238101800017&KeyUID=WOS:000238101800017

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Il-1 beta breaks tolerance through inhibition of regulatory T cell function

Autor: O Sullivan, B., Thomas, H., Jamieson, E., Pai, S., Raymond Steptoe, Kay, T., Thomas, R.

Publikováno v: ResearcherID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c9c8b7806c00f2f158aa983c141d6b67
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000232207802309&KeyUID=WOS:000232207802309

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Functional studies of major histocompatibility class II-positive dendritic cells and resident tissue macrophages isolated from the rat iris

Autor: Raymond Steptoe, Holt, P. G., Mcmenamin, P. G.

Publikováno v: ResearcherID
Scopus-Elsevier

Recent immunomorphological studies have demonstrated the presence of distinct populations of resident tissue macrophages and major histocompatibility complex (MHC) class II+ dendritic cells within tissues lining the anterior chamber of rat, mouse and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2f25b4461faba310b813515de2a749c6
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1995RP57500017&KeyUID=WOS:A1995RP57500017

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