Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Raymond S. Wilson"'
Autor:
Raymond Vazquez, Benjamin W. Lacy, Jon T. Ochikubo, Thomas F. Ditzler, Robert R. Roussel, Thomas M. Martin, Jose M. Pizarro-Matos, Raymond S. Wilson
Publikováno v:
Military medicine. 173(4)
Substance use disorders constitute a serious and persistent threat to military readiness and to the health and safety of military personnel and their families. Methamphetamine is among the most addictive and damaging of commonly abused drugs; this is
Autor:
Billy R. Martin, Everette L. May, Raymond S. Wilson, William L. Dewey, Louis S. Harris, Jacqueline S. Beckner
Publikováno v:
Pharmacology Biochemistry and Behavior. 3:849-853
11-Methy-delta8-, 9-nor-delta8, and 9-nor-delta9-tetrahydrocannabinol (THC), newly synthesized cannabinoids which are not 11-hydroxyated in vivo, were tested for cannabinoid activity. Delta8-, delta9-THC and each synthetic analog produced static atax
Autor:
Raymond S. Wilson, Mathias P. Mertes
Publikováno v:
Biochemistry. 12:2879-2886
Publikováno v:
The Journal of Organic Chemistry. 39:1347-1349
Publikováno v:
Journal of Heterocyclic Chemistry. 6:131-133
Publikováno v:
Journal of medicinal chemistry. 22(7)
A series of compounds was prepared in which the 11-hydroxyl of 11-hydroxy-delta8-THC, the potent metabolite of delta8-THC, was replaced by a methyl, methyoxy, amino, or acetamido group. All of the compounds tested produced behavioral changes in dogs,
Publikováno v:
Chemischer Informationsdienst. 10
A series of compounds was prepared in which the 11-hydroxyl of 11-hydroxy-delta8-THC, the potent metabolite of delta8-THC, was replaced by a methyl, methyoxy, amino, or acetamido group. All of the compounds tested produced behavioral changes in dogs,
Publikováno v:
Chemischer Informationsdienst. 10
A series of 9-hydroxylated cannabinoid-like compounds was prepared and tested for analgesic properties in mice and behavioral properties in dogs. Although the prototype compound, 9-nor-9-hydroxyhexahydrocannabinol, has potent antinociceptive activity
Publikováno v:
Chemischer Informationsdienst. 7
The configuration of the halogen on the C-ring of several α- and β-halomorphides was determined by NMR. The analgesic potencies of these halomorphides and their interactions with narcotic receptors in rat brain homogenate were measured, as was the
Autor:
Kenner C. Rice, Raymond S. Wilson
Publikováno v:
Chemischer Informationsdienst. 7
(-)-3-Isothujone and (+)-3-thujone were examined for antinociceptive activity using the hot-plate and Nilsen tests. In the hot plate test (-)-3-isothujone (ED50 = 6.5 mg/kg) was found to be codeine-like and equipotent with (-)-delta9-tetrahydrocannab