Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Raymond Q. Migrino"'
Autor:
Yining Zhang, Nina Karamanova, Kaleb T. Morrow, Jillian Madine, Seth Truran, Maria Lozoya, Volkmar Weissig, Ming Li, Mehdi Nikkhah, Jin G. Park, Raymond Q. Migrino
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Medin is a common vascular amyloidogenic peptide recently implicated in Alzheimer’s disease (AD) and vascular dementia and its pathology remains unknown. We aim to identify changes in transcriptomic profiles and pathways in human brain mic
Externí odkaz:
https://doaj.org/article/7d468b4c371e4ade9f15a6a89eb164c8
Autor:
Chase Irwin, Donna Tjandra, Chengcheng Hu, Vinod Aggarwal, Amanda Lienau, Bruno Giordani, Jenna Wiens, Raymond Q. Migrino
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION Identifying mild cognitive impairment (MCI) patients at risk for dementia could facilitate early interventions. Using electronic health records (EHRs), we developed a model to predict MCI to all‐cause dementia (ACD) conversion
Externí odkaz:
https://doaj.org/article/02df87a8bd5f4b6dbdfa9050c2035b36
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-12 (2019)
Abstract In vitro three-dimensional (3D) microengineered tissue models have been the recent focus of pathophysiological studies, particularly in the field of cardiovascular research. These models, as classified by 3D biomimetic tissues within microme
Externí odkaz:
https://doaj.org/article/80964466178747c7811e4930af2a78a5
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Background We sought to leverage data routinely collected in electronic health records (EHRs), with the goal of developing patient risk stratification tools for predicting risk of developing Alzheimer's disease (AD). Method Using EHR data fr
Externí odkaz:
https://doaj.org/article/aabf6c31a9294b3b86175d5837fb989e
Autor:
Raymond Q. Migrino, Nina Karamanova, Seth Truran, Geidy E. Serrano, Hannah A. Davies, Jillian Madine, Thomas G. Beach
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Medin, an aging‐associated amyloidogenic protein, induces cerebrovascular dysfunction and inflammation. We investigated the relationship between cerebrovascular medin and Alzheimer's disease (AD) and vascular dementia (VaD). M
Externí odkaz:
https://doaj.org/article/4298e3d248cb4c78a5b46905644e680e
Autor:
Nina Karamanova, Seth Truran, Geidy E. Serrano, Thomas G. Beach, Jillian Madine, Volkmar Weissig, Hannah A. Davies, Jaimeson Veldhuizen, Mehdi Nikkhah, Michael Hansen, Weiyang Zhang, Karen D'Souza, Daniel A. Franco, Raymond Q. Migrino
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 2 (2020)
Background The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content betw
Externí odkaz:
https://doaj.org/article/d05c9fe4b849467391c481a6df8d9070
Autor:
Devendra Goyal, Donna Tjandra, Raymond Q. Migrino, Bruno Giordani, Zeeshan Syed, Jenna Wiens, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 629-637 (2018)
Abstract Introduction Models characterizing intermediate disease stages of Alzheimer's disease (AD) are needed to inform clinical care and prognosis. Current models, however, use only a small subset of available biomarkers, capturing only coarse chan
Externí odkaz:
https://doaj.org/article/c6f5bceb656844189e7b31ee443b8ec6
Autor:
Alejandra Patino-Guerrero, Ruben D. Ponce Wong, Vikram D. Kodibagkar, Wuqiang Zhu, Raymond Q. Migrino, Oliver Graudejus, Mehdi Nikkhah
Publikováno v:
ACS Biomaterials Science & Engineering. 9:944-958
The prevalence of cardiovascular risk factors is expected to increase the occurrence of cardiovascular diseases (CVDs) worldwide. Cardiac organoids are promising candidates for bridging the gap between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8864b43b4bd55f5d72ab5f7c982453
https://doi.org/10.1021/acsbiomaterials.2c01290
https://doi.org/10.1021/acsbiomaterials.2c01290
Autor:
Daniel R, Griffiths, L Matthew, Law, Conor, Young, Alberto, Fuentes, Seth, Truran, Nina, Karamanova, Laura C, Bell, Gregory, Turner, Hannah, Emerson, Diego, Mastroeni, Rayna J, Gonzales, Peter D, Reaven, C Chad, Quarles, Raymond Q, Migrino, Jonathan, Lifshitz
Publikováno v:
Journal of Neurotrauma. 39:1429-1441
Severe traumatic brain injury (TBI) results in cognitive dysfunction in part due to vascular perturbations. In contrast, the long-term vasculo-cognitive pathophysiology of mild TBI (mTBI) remains unknown. We evaluated mTBI effects on chronic cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a453e54de76690a2e16c74de43cb52
https://doi.org/10.1089/neu.2022.0015
https://doi.org/10.1089/neu.2022.0015
Publikováno v:
Alzheimer's & Dementia. 18:2368-2372
Studies investigating the relationship between blood pressure (BP) measurements from electronic health records (EHRs) and Alzheimer's disease (AD) rely on summary statistics, like BP variability, and have only been validated at a single institution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a1278b57b7e0ece0208e2e38dbd041
https://doi.org/10.1002/alz.12676
https://doi.org/10.1002/alz.12676