Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Raymond P. Bain"'
Autor:
Patrick Archdeacon, Roger J. Lewis, Jane Perlmutter, Raymond P. Bain, Miriam Donohue, Karim A. Calis, Annemarie Forrest, John McEachern, Michael J. Pencina, David L. DeMets, M. Khair ElZarrad
Publikováno v:
Clinical Trials. 14:342-348
Background/aims Use of data monitoring committees to oversee clinical trials was first proposed nearly 50 years ago. Since then, data monitoring committee use in clinical trials has increased and evolved. Nonetheless, there are no well-defined criter
Autor:
Michael J. Pencina, Raymond P. Bain, Charles H. Hennekens, Kenneth W. Mahaffey, Marc A. Pfeffer, Janet Wittes, James D. Neaton, Matthew T. Roe, Amit N. Vora, Thomas R. Fleming, David Gordon, Karim A. Calis, Tomas Andersson, Gail D. Pearson, Susan S. Ellenberg, Marvin A. Konstam, David L. DeMets, Alan Meisel
Publikováno v:
Clinical Trials. 14:115-123
Background and Purpose: Data monitoring committees are responsible for safeguarding the interests of study participants and assuring the integrity and credibility of clinical trials. The independence of data monitoring committees from sponsors and in
Autor:
Thomas R Fleming, David L DeMets, Matthew T Roe, Janet Wittes, Karim A Calis, Amit N Vora, Alan Meisel, Raymond P Bain, Marvin A Konstam, Michael J Pencina, David J Gordon, Kenneth W Mahaffey, Charles H Hennekens, James D Neaton, Gail D Pearson, Tomas LG Andersson, Marc A Pfeffer, Susan S Ellenberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f00275f4a82510193f2d4e575ec9ec3
https://europepmc.org/articles/PMC5376229/
https://europepmc.org/articles/PMC5376229/
Autor:
Patrick Archdeacon, Annemarie Forrest, Raymond P. Bain, Jane Perlmutter, Karim A. Calis, David L. DeMets
Publikováno v:
Clinical trials (London, England). 14(1)
Background: The use of data monitoring committees in the conduct of clinical trials has increased and evolved, but there is a lack of published information on when data monitoring committees are needed and utilized, the acceptable range of data monit
Autor:
Oliver Bautista, Raymond P. Bain, Michael K. Brawer, John W. Kusek, Hebert Lepor, Stephen A Sihelnik, Leroy M. Nyberg, Steven A. Kaplan, Gary J. Miller, E. David Crawford, John D. McConnell
Publikováno v:
Controlled Clinical Trials. 24:224-243
Alpha-blockers and 5-alpha-reductase inhibitors are medical therapies that are being used as alternatives to surgical interventions to relieve symptoms of benign prostatic hyperplasia (BPH). Taken as monotherapy, alpha-blockers and 5-alpha-reductase
Publikováno v:
Controlled Clinical Trials. 21:428-439
For safety and ethical reasons, a data monitoring committee of a clinical trial may wish to assess the futility of continuing a trial if the currently available data at an interim look show no beneficial effect due to treatment, especially when accom
Publikováno v:
American Journal of Kidney Diseases. 34:809-817
Diabetic nephropathy is the most common cause of end-stage renal disease in the United States. We undertook a study to assess the impact of assignment to different levels of blood pressure control on the course of type 1 diabetic nephropathy in patie
Autor:
Kenneth Hershon, Barry I. Freedman, Stephen Dippe, Jean-Paul Wuerth, Bruce Spinowitz, Arshag D. Mooradian, Kenneth Cartwright, Raymond P. Bain
Publikováno v:
Controlled Clinical Trials. 20:493-510
Advanced glycosylation endproduct (AGE) formation has been implicated in the development and progression of nephropathy in type 2 diabetes mellitus. In diabetic animals, aminoguanidine inhibits AGE-mediated cross-linking of proteins in vascular and r
Publikováno v:
The American Journal of Clinical Nutrition. 69:366-372
A workshop was convened in 1997 by the National Institutes of Health and the Centers for Disease Control and Prevention to consider the need for and feasibility of conducting a randomized clinical trial to estimate the long-term health effects of int
Autor:
Julia A. Breyer, Raymond P. Bain, Joni K. Evans, N. Stanley Nahman, Edmund J. Lewis, Melisa Cooper, Janet McGill, Tomas Berl, null The Collaborative Study Group
Publikováno v:
Kidney International. 50(5):1651-1658
Predictors of the progression of renal insufficiency in patients with insulin-dependent diabetes and overt diabetic nephropathy. We designed a prospective, double-blind controlled trial to determine predictors of loss of renal function in patients wi