Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Raymond Meleady"'
Autor:
Ian D. Graham, Raymond Meleady
Publikováno v:
European Journal of Cardiovascular Prevention & Rehabilitation. 5:233-237
There is now abundant evidence that elevated plasma total homocysteine is a risk factor for vascular disease in general and for cardiovascular disease in particular. Plasma concentrations of homocysteine are modulated by both genetic and environmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::938b9d750a92797fe3a225bbbf223c4c
https://doi.org/10.1177/174182679800500405
https://doi.org/10.1177/174182679800500405
Autor:
Raymond Meleady, Roberto Palma-Reis, Helga Refsum, Ian D. Graham, Leslie Daly, Jacqueline C.M. Witteman, Godfried H.J. Boers, Lars Brattström, Paolo Rubba, Kristopher L. Arheart, Killian Robinson, Per Magne Ueland
Publikováno v:
Circulation. 97:437-443
Background —A high plasma homocysteine concentration is a risk factor for atherosclerosis, and circulating concentrations of homocysteine are related to levels of folate and vitamin B 6 . This study was performed to explore the interrelationships b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54d6afba5292a5faffee7d7dea8672db
https://doi.org/10.1161/01.cir.97.5.437
https://doi.org/10.1161/01.cir.97.5.437
Autor:
Ian D. Graham, Raymond Meleady, Rima Rozen, Alun Evans, Denis C. Shields, Kok Soon Tan, Alexander S. Whitehead, Dorothy McMaster, Paula M. Gallagher
Publikováno v:
Circulation. 94:2154-2158
Background Plasma homocysteine levels are modulated by nutritional and genetic factors, among which is the enzyme methylenetetrahydrofolate reductase (MTHFR). A common defective (thermolabile) variant of this enzyme is causally associated with elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2e3d95547d63f98142215a47c6d5c1
https://doi.org/10.1161/01.cir.94.9.2154
https://doi.org/10.1161/01.cir.94.9.2154
Autor:
Ian D. Graham, Raymond Meleady
Publikováno v:
European Journal of Cardiovascular Prevention & Rehabilitation. 2:216-221
This article reviews the evidence that homocysteine is a risk factor for coronary artery disease. This evidence ranges from that obtained from in-vitro experiments sometimes using non-physiological concentrations of homocysteine to epidemiological st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10dc0647e9b9d8ff5fb48cf15a1e412e
https://doi.org/10.1177/174182679500200306
https://doi.org/10.1177/174182679500200306
Autor:
Ying Zhang, Cait Donohue, Henk J. Blom, Anne-Lise Bjørke Monsen, Raymond Meleady, Alexander S. Whitehead, Leslie Daly, Arve Ulvik, Ian D. Graham, Stein Emil Vollset, Per Magne Ueland, Belinda A. J. Giesendorf, Helga Refsum
Publikováno v:
The American Journal of Clinical Nutrition, 77, 1, pp. 63-70
The American Journal of Clinical Nutrition, 77, 63-70
The American Journal of Clinical Nutrition, 77, 63-70
Item does not contain fulltext BACKGROUND: Homozygotes for the thermolabile mutation (TT genotype) of the methylenetetrahydrofolate reductase (MTHFR; EC 1.5.1.20) enzyme have elevated plasma concentrations of the cardiovascular disease risk factor ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fe86ca23116aa2f0855741cd51d997
https://pubmed.ncbi.nlm.nih.gov/12499324
https://pubmed.ncbi.nlm.nih.gov/12499324
Autor:
Alexander S. Whitehead, I M Graham, M Karabatzaki, Raymond Meleady, L. Mynett-Johnson, Mark Cahill, C Donoghue, David J. Mooney, Denis C. Shields
Background—Raised levels of total plasma homocysteine (tHcy) are associated with an increased risk of retinal vascular occlusive disease. A thermolabile form of a pivotal enzyme in homocysteine metabolism, methylenetetrahydrofolate reductase (MTHFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad788ec5a293fd14f43c559b7bebc3aa
https://europepmc.org/articles/PMC1723690/
https://europepmc.org/articles/PMC1723690/
Autor:
Ian D. Graham, Raymond Meleady
Publikováno v:
Nutrition reviews. 57(10)
Elevated plasma total homocysteine may be causally related to the risk of atherosclerotic cardio-vascular diseases. Many significant studies indicate an effect by elevated homocysteine on cardiovascular disease occurrence, progression, and recurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19927010cd67e283d52af9bf5a0ac0b8
https://pubmed.ncbi.nlm.nih.gov/10575905
https://pubmed.ncbi.nlm.nih.gov/10575905
Autor:
Rosemary Barry, Marguerite Doyle, Rachael M. Doyle, Dawn L. Harmon, Davis Coakley, Alexander S. Whitehead, Denis C. Shields, Ian D. Graham, Raymond Meleady
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 19(2)
Abstract —Mild hyperhomocysteinemia is a risk factor for atherosclerotic vascular disease. Homozygosity for the C677T mutation in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR) is frequently associated with hyperhomocysteinemia, part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895f972e741a5acdac9dbc5eba689b11
https://pubmed.ncbi.nlm.nih.gov/9974399
https://pubmed.ncbi.nlm.nih.gov/9974399
Publikováno v:
European Heart Journal 20 (1999)
European Heart Journal, 20, 1234-1244
European Heart Journal, 20, 1234-1244
Background Elevated plasma total homocysteine (tHcy) is a known risk factor for vascular disease. Gender, age, and circulating levels of folate, vitamins B6and B12affect tHcy levels. Objectives To study associations of gender and age with levels of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f213a70de3cf9d8c1346e5e1df27435e
https://research.wur.nl/en/publications/homocysteine-vitamin-status-and-risk-of-vascular-disease-effects-
https://research.wur.nl/en/publications/homocysteine-vitamin-status-and-risk-of-vascular-disease-effects-
Autor:
I.M. Higgins, Richard G. Sheahan, Petra Verhoef, Jacqueline C.M. Witteman, Lars Brattström, Generoso Andria, Godfried H.J. Boers, Cuno S. P. M. Uiterwaal, I. M. Graham, Bo Israelsson, Armando C. Sales Luis, Jan C. Wautrecht, Hélène Bellet, Dorothy McMaster, Killian Robinson, Leslie Daly, P M Ueland, Maria José Medrano, Roberto Palma-Reis, Raymond Meleady, Paolo Rubba, Mirande Candito, Françoise Parrot-Rouland, Harold W. De Valk, Helga Refsum, Alun Evans, Danielle Garcon, Kok Soon Tan
Publikováno v:
Developments in Cardiovascular Medicine ISBN: 9781461376453
Aterosclerotic cardiovascular disease, notably coronary heart disease, remains the major cause of death in developed countries [1]. A high-fat diet, hypertension, and smoking are regarded as causal factors [2], and changes in these factors appear to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb65188b6417ecd36afca2e64eec2f1
https://doi.org/10.1007/978-1-4615-5771-5_31
https://doi.org/10.1007/978-1-4615-5771-5_31