Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Raymond M. Gipson"'
Publikováno v:
Liquid Crystals. :1-10
One of us (AJS) was fortunate enough to have known Professor George Gray during his final years of teaching at the University of Hull. In 1989, I was finishing my undergraduate studies when I sat in George's class entitled Proteins and Polypeptides.
Autor:
Raymond M. Gipson, Timothy R. Donahue, Jason T. Lee, Harvey R. Herschman, Liu Wei, Thuc Le, Arnon Lavie, Saman Sadeghi, Michael E. Phelps, Nhu T. Uong, Woosuk Kim, Shahriar S. Yaghoubi, Jimmy Bazzy, Caius G. Radu, Evan R. Abt, Kym F. Faull, Anthony E. Cabebe, Soumya Poddar, Roger Slavik, Joseph R. Capri, Thotsophon Taechariyakul, Juno Van Valkenburgh, Wayne R. Austin, Ken Herrmann, Xuemeng Wang, Owen N. Witte, Dalton Steele, Johannes Czernin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 15
Deoxycytidine kinase (dCK), a rate-limiting enzyme in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positron emission tomography (PET) imaging target in cancer. PET probes for dCK have been developed and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfde460dddeac19dc63993feeae682dd
https://escholarship.org/uc/item/5df0b26k
https://escholarship.org/uc/item/5df0b26k
Publikováno v:
Liquid Crystals. 37:101-108
The synthesis of a family of alkyl 5-(4-hexyloxyphenyl)thieno[3,2-b]thiophene-2-carboxylate liquid crystals is described. The synthetic methodology utilised includes a Fiesselmann synthesis of the thieno[3,2-b]thiophene core, and the first report of
Autor:
Tony Smith, Bernard D. Santarsiero, Arnon Lavie, Amanda L. Armijo, Johannes Czernin, Jue Wang, Michael E. Jung, Hien Anh Nguyen, Caius G. Radu, Thuc Le, Raymond M. Gipson, Julian Nomme, Zheng Li, Anastassia N. Alexandrova, Soumya Poddar
Publikováno v:
Journal of medicinal chemistry, vol 57, iss 22
Journal of Medicinal Chemistry
Nomme, J; Li, Z; Gipson, RM; Wang, J; Armijo, AL; Le, T; et al.(2014). Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. Journal of Medicinal Chemistry, 57(22), 9480-9494. doi: 10.1021/jm501124j. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9fv4j1bs
Journal of Medicinal Chemistry
Nomme, J; Li, Z; Gipson, RM; Wang, J; Armijo, AL; Le, T; et al.(2014). Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. Journal of Medicinal Chemistry, 57(22), 9480-9494. doi: 10.1021/jm501124j. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9fv4j1bs
© 2014 American Chemical Society. Recently, we have shown that small molecule dCK inhibitors in combination with pharmacological perturbations of de novo dNTP biosynthetic pathways could eliminate acute lymphoblastic leukemia cells in animal models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed3f11060d74e247782e3622cb5968a
https://escholarship.org/uc/item/9fv4j1bs
https://escholarship.org/uc/item/9fv4j1bs
Autor:
Nicholas M. Matsumoto, Heather D. Maynard, Raymond M. Gipson, Selma Duhović, Brianna M. Upton, Brian R. Lydon, Paula L. Diaconescu
Publikováno v:
Upton, BM; Gipson, RM; Duhović, S; Lydon, BR; Matsumoto, NM; Maynard, HD; et al.(2014). Synthesis of ferrocene-functionalized monomers for biodegradable polymer formation. Inorganic Chemistry Frontiers, 1(3), 271-277. doi: 10.1039/c3qi00041a. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4h9722mj
Inorganic Chemistry Frontiers, vol 1, iss 3
Inorganic Chemistry Frontiers, vol 1, iss 3
This journal is © the Partner Organisations 2014. Cyclic carbonate and δ-valerolactone substrates functionalized with ferrocene were synthesized via alkyne-azide "click" cycloaddition. The cyclic carbonates were polymerized using 1,8-diazabicycloun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d0c6f2a9ffe45be54a224c5d69d01
http://www.escholarship.org/uc/item/4h9722mj
http://www.escholarship.org/uc/item/4h9722mj