Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Raymond L Mernaugh"'
Autor:
Keiko Takahashi, Katherine Sumarriva, Rachel Kim, Rosie Jiang, Dana M Brantley-Sieders, Jin Chen, Raymond L Mernaugh, Takamune Takahashi
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154916 (2016)
CD148 is a transmembrane protein tyrosine phosphatase that is expressed in multiple cell types, including vascular endothelial cells and duct epithelial cells. Previous studies have shown a prominent role of CD148 to reduce growth factor signals and
Externí odkaz:
https://doaj.org/article/4c3d21522e9648468c2f1f37a5d9df9e
Autor:
Nicole F Neel, Jiqing Sai, Amy-Joan L Ham, Tammy Sobolik-Delmaire, Raymond L Mernaugh, Ann Richmond
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23813 (2011)
Chemotaxis is essential for a number of physiological processes including leukocyte recruitment. Chemokines initiate intracellular signaling pathways necessary for chemotaxis through binding seven transmembrane G protein-couple receptors. Little is k
Externí odkaz:
https://doaj.org/article/2bab39ab5da447f18f05055eca573578
Autor:
Lilly He, Keiko Takahashi, Lejla Pasic, Raymond L. Mernaugh, Rachel H. Kim, Takamune Takahashi, Raymond C. Harris, Tracy May, Shinya Nagasaka, Akira Shimizu, Daisuke Katagiri
Publikováno v:
Am J Physiol Renal Physiol
CD148 is a transmembrane protein tyrosine phosphatase (PTP) that is expressed in the renal vasculature, including the glomerulus. Previous studies have shown that CD148 plays a role in the negative regulation of growth factor signals (including epide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c351014fb7e3c14fbfe785a8dc1f9bc5
https://doi.org/10.1152/ajprenal.00288.2019
https://doi.org/10.1152/ajprenal.00288.2019
Autor:
Lejla Pasic, Annet Kirabo, Sean S. Davies, Justin H. Layer, Alan J. Simmons, Cassandra Warden, Raymond L. Mernaugh
Publikováno v:
Journal of Visualized Experiments.
Isolevuglandins (IsoLGs) are highly reactive gamma ketoaldehydes formed from H2-isoprostanes through lipid peroxidation and crosslink proteins leading to inflammation and various diseases including hypertension. Detection of IsoLG accumulation in tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8deda9c7bf1e3f538061f10efa91405
https://doi.org/10.3791/62603
https://doi.org/10.3791/62603
Autor:
Raymond L. Mernaugh, Mingxiao Hou, Dongzhi Wang, Wenhui Yue, Samuel C. Dudley, Xinyu Weng, Yingjie Chen, E. Kenneth Weir, Linlin Shang, Yawei Xu, Venkataraman Amarnath
Publikováno v:
Free Radical Biology and Medicine. 141:291-298
Increased levels of reactive isolevuglandins (IsoLGs) are associated with vascular inflammation and hypertension, two important factors affect heart failure (HF) development. The role of IsoLGs in HF development is unknown. Here we studied the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cccea4ac19a9e40276beec978d9e57cd
https://doi.org/10.1016/j.freeradbiomed.2019.06.029
https://doi.org/10.1016/j.freeradbiomed.2019.06.029
Publikováno v:
Biosensors, Vol 10, Iss 71, p 71 (2020)
Biosensors
Volume 10
Issue 6
Biosensors
Volume 10
Issue 6
Enzyme-catalyzed chemical reactions produce heat. We developed an enclosed, capillary-perfused nanocalorimeter platform for thermometric enzyme-linked immunosorbent assay (TELISA). We used catalase as enzymes to model the thermal characteristics of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9b25e67667d9b7d0f77e8014e76ff0
https://www.mdpi.com/2079-6374/10/6/71
https://www.mdpi.com/2079-6374/10/6/71
Autor:
Ashley Pitzer, Luciana Simao do Carmo, Natalia R. Barbaro, Justin P Van Beusecum, David G. Harrison, Aseel Alsouqi, Heitor Moreno, Wei Chen, Kim Ramil C. Montaniel, Cristi L. Galindo, Raymond L. Mernaugh, Annet Kirabo, Fernando Elijovich, Jason D. Foss, Cheryl L. Laffer, Agnes B. Fogo, Talat Alp Ikizler, Mingfang Ao, Liang Xiao, Sean S. Davies, Shilin Zhao, Roxana Loperena
Publikováno v:
Cardiovascular Research
Aims Prior studies have focused on the role of the kidney and vasculature in salt-induced modulation of blood pressure; however, recent data indicate that sodium accumulates in tissues and can activate immune cells. We sought to examine mechanisms by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63bee84ace0734576ab095aad4d4939
https://pubmed.ncbi.nlm.nih.gov/33038226
https://pubmed.ncbi.nlm.nih.gov/33038226
Autor:
Sharon M. Weiss, Scott T. Retterer, Shuren Hu, Girija Gaur, Raymond L. Mernaugh, Ivan I. Kravchenko
Publikováno v:
Sensors and Actuators B: Chemical. 275:394-401
Highly sensitive detection of heat denatured Herceptin® (trastuzumab), an important monoclonal antibody used in breast cancer therapeutics, is demonstrated using transverse magnetic (TM) mode suspended microring resonators (MRRs). The suspended MRRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918fa73a7ee7f33ae7a52bda5f0a701a
https://doi.org/10.1016/j.snb.2018.07.081
https://doi.org/10.1016/j.snb.2018.07.081
Autor:
Natalia R. Barbaro, Bjorn C. Knollmann, Annet Kirabo, Jens Titze, Shivani Kumaresan, Liang Xiao, Dmytro O. Kryshtal, Wei Chen, David G. Harrison, Raymond L. Mernaugh, Hana A. Itani, Sergey Dikalov, Jason D. Foss, Roxana Loperena, Nikita Tsyba
Publikováno v:
Cell reports
Cell Reports, Vol 21, Iss 4, Pp 1009-1020 (2017)
Cell Reports, Vol 21, Iss 4, Pp 1009-1020 (2017)
SUMMARY Sodium accumulates in the interstitium and promotes inflammation through poorly defined mechanisms. We describe a pathway by which sodium enters dendritic cells (DCs) through amiloride-sensitive channels including the alpha and gamma subunits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb2bdb60a4131b298ef0d1c90b054ba
https://doi.org/10.1016/j.celrep.2017.10.002
https://doi.org/10.1016/j.celrep.2017.10.002
Publikováno v:
Biomedical microdevices. 21(4)
Advances in microfabrication allow for highly sensitive calorimeters with dramatically reduced volume, decreased response time and increased energy resolution. These calorimeters hold the potential for designs of ELISA platforms competitive with fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df409648c1c5bb9d15dee121b3a8ce36
https://pubmed.ncbi.nlm.nih.gov/31451947
https://pubmed.ncbi.nlm.nih.gov/31451947