Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Raymond H. J. Staals"'
Autor:
Despoina Trasanidou, Ana Potocnik, Patrick Barendse, Prarthana Mohanraju, Evgenios Bouzetos, Efthymios Karpouzis, Amber Desmet, Richard van Kranenburg, John van der Oost, Raymond H. J. Staals, Ioannis Mougiakos
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Anti-CRISPR proteins (Acrs) block the activity of CRISPR-associated (Cas) proteins, either by inhibiting DNA interference or by preventing crRNA loading and complex formation. Although the main use of Acrs in genome engineering applications
Externí odkaz:
https://doaj.org/article/f440bd2a17af489fb61d09f20fca172a
Autor:
Jurre A. Steens, Yifan Zhu, David W. Taylor, Jack P. K. Bravo, Stijn H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, Michel Ossendrijver, L. Marije Hofstra, Stan J. J. Brouns, Akeo Shinkai, John van der Oost, Raymond H. J. Staals
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Type III CRISPR-Cas systems recognize and cleave target RNAs and produce signalling molecules. Here the authors discover that both processes are governed by a flexible seed region, ultimately resulting in SCOPE, a SARSCoV-2 diagnostic assay with atto
Externí odkaz:
https://doaj.org/article/e3174dc9798f445a945c96d9e82fdcc7
Autor:
Raymond H. J. Staals, Simon A. Jackson, Ambarish Biswas, Stan J. J. Brouns, Chris M. Brown, Peter C. Fineran
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Prokaryotic CRISPR-Cas systems provide adaptive immunity against foreign nucleic acids by acquiring short, invader-derived sequences called spacers. Here, Staals et al. analyse millions of such events in a native CRISPR-Cas system, showing that newly
Externí odkaz:
https://doaj.org/article/2b405c24d7584a81b02d85c2c41648d7
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT A powerful contributor to prokaryotic evolution is horizontal gene transfer (HGT) through transformation, conjugation, and transduction, which can be advantageous, neutral, or detrimental to fitness. Bacteria and archaea control HGT and phag
Externí odkaz:
https://doaj.org/article/b1081660118546c791dce1a0a6a6135e
Autor:
Luis Garcia Morales, Niek H A Savelkoul, Zoë Robaey, Nico J Claassens, Raymond H J Staals, Robert W Smith
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009916 (2022)
Externí odkaz:
https://doaj.org/article/96e72b2f79e8494997d5779c86022434
Autor:
Prarthana Mohanraju, Chinmoy Saha, Peter van Baarlen, Rogier Louwen, Raymond H. J. Staals, John van der Oost
Publikováno v:
Nature Reviews Microbiology 20 (2022) 6
Nature Reviews Microbiology, 20(6), 351-364
Nature Reviews Microbiology, 20(6), 351-364
CRISPR–Cas systems of bacteria and archaea comprise chromosomal loci with typical repetitive clusters and associated genes encoding a range of Cas proteins. Adaptation of CRISPR arrays occurs when virus-derived and plasmid-derived sequences are int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615c9476f053813b6f439b0f84bba766
https://research.wur.nl/en/publications/alternative-functions-of-crisprcas-systems-in-the-evolutionary-ar
https://research.wur.nl/en/publications/alternative-functions-of-crisprcas-systems-in-the-evolutionary-ar
Autor:
Prarthana, Mohanraju, Chinmoy, Saha, Peter, van Baarlen, Rogier, Louwen, Raymond H J, Staals, John, van der Oost
Publikováno v:
Nature reviews. Microbiology. 20(6)
CRISPR-Cas systems of bacteria and archaea comprise chromosomal loci with typical repetitive clusters and associated genes encoding a range of Cas proteins. Adaptation of CRISPR arrays occurs when virus-derived and plasmid-derived sequences are integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59b7e98133fa657ec384d009535bee75
https://pubmed.ncbi.nlm.nih.gov/34992260
https://pubmed.ncbi.nlm.nih.gov/34992260
Autor:
Adrian G, Patterson, Simon A, Jackson, Corinda, Taylor, Gary B, Evans, George P C, Salmond, Rita, Przybilski, Raymond H J, Staals, Peter C, Fineran
Publikováno v:
Molecular cell. 64(6)
Bacteria commonly exist in high cell density populations, making them prone to viral predation and horizontal gene transfer (HGT) through transformation and conjugation. To combat these invaders, bacteria possess an arsenal of defenses, such as CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::689592daa77c6adddc687f8700c34f82
https://pubmed.ncbi.nlm.nih.gov/27984739
https://pubmed.ncbi.nlm.nih.gov/27984739
Autor:
Raymond H J, Staals, Ger J M, Pruijn
Publikováno v:
Advances in experimental medicine and biology. 702
Long before the RNA degrading exosome was first described in the yeast Saccharomyces cerevisiae, the use of autoantibodies found in the sera of certain autoimmune patients allowed the identification of a complex of polypeptides which later appeared t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::69988e49e22dfa17418fa31fa207013c
https://pubmed.ncbi.nlm.nih.gov/21713683
https://pubmed.ncbi.nlm.nih.gov/21713683
Autor:
Robert A M, Vreeburg, Joris J, Benschop, Anton J M, Peeters, Timothy D, Colmer, Ankie H M, Ammerlaan, Marten, Staal, Theo M, Elzenga, Raymond H J, Staals, Catherine P, Darley, Simon J, McQueen-Mason, Laurentius A C J, Voesenek
Publikováno v:
The Plant journal : for cell and molecular biology. 43(4)
The semi-aquatic dicot Rumex palustris responds to complete submergence by enhanced elongation of young petioles. This elongation of petiole cells brings leaf blades above the water surface, thus reinstating gas exchange with the atmosphere and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02779e4b711d985c99aa0736abdc3239
https://pubmed.ncbi.nlm.nih.gov/16098112
https://pubmed.ncbi.nlm.nih.gov/16098112