Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Raymond G. Fox"'
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MYC amplification is an independent prognostic factor for the most aggressive subgroup (Group 3) of pediatric medulloblastoma (G3 MB). Here, the authors highlight the role of the RNA-binding protein, Musashi-1 (MSI1) in G3 MB and identify MSI1-bound
Externí odkaz:
https://doaj.org/article/3eace71e4f774decb598d79c690ed3aa
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a3f8e3d5b4894e4aa4350454d71f0f4e
Autor:
Claire S. Koechlein, Jeffrey R. Harris, Timothy K. Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus W. Covert, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
It is difficult to image haematopoietic stem cells (HSC) in their niche. Here, the authors present a new high-throughput computational approach to visualise HSCs in vivoat a high spatial and temporal resolution and also use a Msi2-reporter to label e
Externí odkaz:
https://doaj.org/article/eb98c9dbcd7d47d28ac28ab4c7bfb28b
Publikováno v:
Cancer Research. 82:LB144-LB144
Leydig cell tumors (LCT), originating from androgen-producing interstitial Leydig cells of the testis, represent about 3% of all testicular cancers. LCT belong to the family of sex cord stromal tumors (SCST), a collection of tumors formed in the supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6b74dd25c2a62e15a99ef98e09ff734
https://doi.org/10.1158/1538-7445.am2022-lb144
https://doi.org/10.1158/1538-7445.am2022-lb144
Autor:
Michael Hamilton, Trey Ideker, Haiyong Han, Sara Brin Rosenthal, Christian M. Schürch, Roman Sasik, Kathleen M. Fisch, Nikki K. Lytle, Andrew M. Lowy, Marcie Kritzik, Lourdes A Esparza, Wei Lin, Neil Robertson, Randall French, Nathan E. Lewis, L. Paige Ferguson, Evanthia Karamitopoulou, Philipp Spahn, Martin Wartenberg, Yutaka Shima, Micha Eichmann, Anagha Deshpande, Kathryn Gilroy, Peter D. Adams, José A. Galván, Raymond G. Fox, Inti Zlobec, Tami Gilderman, Tannishtha Reya, Aniruddha J. Deshpande, Pawan Noel, Daniel D. Von Hoff, Nirakar Rajbhandari
Publikováno v:
Cell, vol 177, iss 3
Drug resistance and relapse remain key challenges inpancreatic cancer. Here, we have used RNA sequencing (RNA-seq), chromatin immunoprecipitation (ChIP)-seq, and genome-wide CRISPR analysis to map the molecular dependencies of pancreatic cancer stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1439315728d601799b93bc272a2db8f9
https://escholarship.org/uc/item/1vq502nm
https://escholarship.org/uc/item/1vq502nm
Autor:
David Bakhshinyan, Marc Remke, En-Ching Luo, Kristin Hope, Provias John, Sansi Xing, Raymond G. Fox, Jason Moffat, Gene W. Yeo, Yu Lu, Frederick E. Tan, Ashley Adile, Chitra Venugopal, Helen He Zhu, Kevin R. Brown, Brian A. Yee, Minomi Subapanditha, Jüri Reimand, Agata Xella, Tannishitha Reya, Adam Fleming, Michelle Kameda-Smith, Robert J. Wechsler-Reya, Daniel Picard, Sheila K. Singh
Publikováno v:
Neuro-Oncology
Medulloblastoma (MB) is the most common solid malignant pediatric brain neoplasm, with Group 3 (G3) MB representing the most aggressive subgroup. MYC amplification is an independent poor prognostic factor in G3 MB, however, therapeutic targeting of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d62f398119b5f1086b87754a1af009
http://europepmc.org/articles/PMC7715904
http://europepmc.org/articles/PMC7715904
Autor:
Markus W. Covert, John P. Chute, Tannishtha Reya, Takahiro Ito, Joi Weeks, Jeffrey R. Harris, Claire S. Koechlein, Timothy K. Lee, Bryan Zimdahl, Allen Blevins, Seung-Hye Jung, Raymond G. Fox, Amit Chourasia
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Although we know a great deal about the phenotype and function of haematopoietic stem/progenitor cells, a major challenge has been mapping their dynamic behaviour within living systems. Here we describe a strategy to image cells in vivo with high spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b163a595cfd00424e9c1d56b26aa62d
https://doi.org/10.1038/ncomms12169
https://doi.org/10.1038/ncomms12169
Autor:
Jose M. Arbones-Mainar, Michael K. Altenburg, Hyung Suk Kim, Avani A. Pendse, Nobuyo Maeda, Lance A. Johnson, Raymond G. Fox
Publikováno v:
Diabetes
OBJECTIVE We investigated the differential roles of apolipoprotein E (apoE) isoforms in modulating diabetic dyslipidemia—a potential cause of the increased cardiovascular disease risk of patients with diabetes. RESEARCH DESIGN AND METHODS Diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698913f3969c89e0d34eb65ab3757700
http://europepmc.org/articles/PMC3161311
http://europepmc.org/articles/PMC3161311
Publikováno v:
Annual review of cell and developmental biology. 31
How a single cell gives rise to an entire organism is one of biology's greatest mysteries. Within this process, stem cells play a key role by serving as seed cells capable of both self-renewal to sustain themselves as well as differentiation to gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2902dfa38181f80b2a6b95b426ba3bde
https://pubmed.ncbi.nlm.nih.gov/26566113
https://pubmed.ncbi.nlm.nih.gov/26566113
Autor:
Trenis Palmer, Raymond G. Fox, Tannishtha Reya, Lesley G. Ellies, Joan Font-Burgada, Steven F. Dowdy, Qing Xie, Michael Karin, Alexander S. Hamil, Weizhou Zhang, Jing Yang, Nicholas Borcherding, Xuefeng Wu, Nikki K. Lytle, Subhra K. Biswas, Li Wha Wu, Michael Poidinger
Publikováno v:
Wu, X; Zhang, W; Font-Burgada, J; Palmer, T; Hamil, AS; Biswas, SK; et al.(2014). Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. Proceedings of the National Academy of Sciences of the United States of America, 111(38), 13870-13875. doi: 10.1073/pnas.1414358111. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0p77n28j
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 38
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 38
Metastatic spread is the leading cause of cancer mortality. Breast cancer (BCa) metastatic recurrence can happen years after removal of the primary tumor. Here we show that Ubc13, an E2 enzyme that catalyzes K63-linked protein polyubiquitination, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8908ccc486ff4d92ef049fa54192ab9
http://www.escholarship.org/uc/item/0p77n28j
http://www.escholarship.org/uc/item/0p77n28j