Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Raymond G Sierra"'
Autor:
Halil I Ciftci, Raymond G Sierra, Chun Hong Yoon, Zhen Su, Hiroshi Tateishi, Ryoko Koga, Koiwai Kotaro, Fumiaki Yumoto, Toshiya Senda, Mengling Liang, Soichi Wakatsuki, Masami Otsuka, Mikako Fujita, Hasan DeMirci
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1675 (2019)
The Human immunodeficiency virus-1 (HIV-1) matrix (MA) domain is involved in the highly regulated assembly process of the virus particles that occur at the host cell’s plasma membrane. High-resolution structures of the MA domain determined using cr
Externí odkaz:
https://doaj.org/article/db67ecf9967c4cb6be9ba3288569154d
Autor:
Izumi Ishigami, Raymond G. Sierra, Zhen Su, Ariana Peck, Cong Wang, Frederic Poitevin, Stella Lisova, Brandon Hayes, Frank R. Moss, Sébastien Boutet, Robert E. Sublett, Chun Hong Yoon, Syun-Ru Yeh, Denis L. Rousseau
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Cytochrome c oxidase (CcO) is an essential enzyme in mitochondrial and bacterial respiration. It catalyzes the four-electron reduction of molecular oxygen to water and harnesses the chemical energy to translocate four protons across biologic
Externí odkaz:
https://doaj.org/article/4cf0387559044a58973e6bfc59f08ca6
Autor:
Tek Narsingh Malla, Kara Zielinski, Luis Aldama, Sasa Bajt, Denisse Feliz, Brendon Hayes, Mark Hunter, Christopher Kupitz, Stella Lisova, Juraj Knoska, Jose Manuel Martin-Garcia, Valerio Mariani, Suraj Pandey, Ishwor Poudyal, Raymond G. Sierra, Alexandra Tolstikova, Oleksandr Yefanov, Chung Hong Yoon, Abbas Ourmazd, Petra Fromme, Peter Schwander, Anton Barty, Henry N. Chapman, Emina A. Stojkovic, Alexander Batyuk, Sébastien Boutet, George N. Phillips, Lois Pollack, Marius Schmidt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract For decades, researchers have elucidated essential enzymatic functions on the atomic length scale by tracing atomic positions in real-time. Our work builds on possibilities unleashed by mix-and-inject serial crystallography (MISC) at X-ray f
Externí odkaz:
https://doaj.org/article/50042ef4cec14678ac809352eb19f238
Autor:
Guillaume Tetreau, Michael R. Sawaya, Elke De Zitter, Elena A. Andreeva, Anne-Sophie Banneville, Natalie A. Schibrowsky, Nicolas Coquelle, Aaron S. Brewster, Marie Luise Grünbein, Gabriela Nass Kovacs, Mark S. Hunter, Marco Kloos, Raymond G. Sierra, Giorgio Schiro, Pei Qiao, Myriam Stricker, Dennis Bideshi, Iris D. Young, Ninon Zala, Sylvain Engilberge, Alexander Gorel, Luca Signor, Jean-Marie Teulon, Mario Hilpert, Lutz Foucar, Johan Bielecki, Richard Bean, Raphael de Wijn, Tokushi Sato, Henry Kirkwood, Romain Letrun, Alexander Batyuk, Irina Snigireva, Daphna Fenel, Robin Schubert, Ethan J. Canfield, Mario M. Alba, Frédéric Laporte, Laurence Després, Maria Bacia, Amandine Roux, Christian Chapelle, François Riobé, Olivier Maury, Wai Li Ling, Sébastien Boutet, Adrian Mancuso, Irina Gutsche, Eric Girard, Thomas R. M. Barends, Jean-Luc Pellequer, Hyun-Woo Park, Arthur D. Laganowsky, Jose Rodriguez, Manfred Burghammer, Robert L. Shoeman, R. Bruce Doak, Martin Weik, Nicholas K. Sauter, Brian Federici, Duilio Cascio, Ilme Schlichting, Jacques-Philippe Colletier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
An environmentally safe means of mosquito control is the application of Bacillus thuringiensis israelensis, which produces a cocktail of four naturally crystalline proteins exclusively toxic to mosquito. Here the authors report the atomic-resolution
Externí odkaz:
https://doaj.org/article/8dead0f985474ca8a66f02736c28391a
Autor:
Michelle R. Santoso, Gentaro Ikeda, Yuko Tada, Ji‐Hye Jung, Evgeniya Vaskova, Raymond G. Sierra, Cornelius Gati, Andrew B. Goldstone, Daniel von Bornstaedt, Praveen Shukla, Joseph C. Wu, Soichi Wakatsuki, Y. Joseph Woo, Phillip C. Yang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 6 (2020)
Background Induced pluripotent stem cells and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient‐specific therapy for ischemic cardiomyopathy following myocardial infarctions, but difficulties in viable transplantation
Externí odkaz:
https://doaj.org/article/b4461a47d1114db3b17f62e80a4ff925
Autor:
Omur Guven, Mehmet Gul, Esra Ayan, J Austin Johnson, Baris Cakilkaya, Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Busra Yuksel, Oktay Gocenler, Cengizhan Buyukdag, Sabine Botha, Gihan Ketawala, Zhen Su, Brandon Hayes, Frederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, Serdar Durdagi, Raymond G. Sierra, Hasan DeMirci
Publikováno v:
Crystals, Vol 11, Iss 12, p 1579 (2021)
Since early 2020, COVID-19 has grown to affect the lives of billions globally. A worldwide investigation has been ongoing for characterizing the virus and also for finding an effective drug and developing vaccines. As time has been of the essence, a
Externí odkaz:
https://doaj.org/article/304b6058372a49cd8edb08044f9a1e25
Autor:
Shalina Taylor, Sarasa Isobe, Aiqin Cao, Kévin Contrepois, Bérénice A. Benayoun, Lihua Jiang, Lingli Wang, Stavros Melemenidis, Mehmet O. Ozen, Shoichiro Otsuki, Tsutomu Shinohara, Andrew J. Sweatt, Jordan Kaplan, Jan-Renier Moonen, David P. Marciano, Mingxia Gu, Kazuya Miyagawa, Brandon Hayes, Raymond G. Sierra, Christopher J. Kupitz, Patricia A. Del Rosario, Andrew Hsi, A. A. Roger Thompson, Maria E. Ariza, Utkan Demirci, Roham T. Zamanian, Francois Haddad, Mark R. Nicolls, Michael P. Snyder, Marlene Rabinovitch
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1019-1034
Rationale: The role of neutrophils and their extracellular vesicles (EVs) in the pathogenesis of pulmonary arterial hypertension is unclear. Objectives: Relate functional abnormalities in pulmonary arterial hypertension neutrophils and their EVs to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a69d63632739333b28d4a5d6ec5adec
https://doi.org/10.1164/rccm.202102-0446oc
https://doi.org/10.1164/rccm.202102-0446oc
Autor:
Emily K. Tsang, Nathan S. Abell, Xin Li, Vanessa Anaya, Konrad J. Karczewski, David A. Knowles, Raymond G. Sierra, Kevin S. Smith, Stephen B. Montgomery
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 31-39 (2017)
Exosomes are small extracellular vesicles that carry heterogeneous cargo, including RNA, between cells. Increasing evidence suggests that exosomes are important mediators of intercellular communication and biomarkers of disease. Despite this, the var
Externí odkaz:
https://doaj.org/article/9008996f7e0b48c48d88b1368237700a
Autor:
Izumi Ishigami, Sergio Carbajo, Nadia Zatsepin, Masahide Hikita, Chelsie E. Conrad, Garrett Nelson, Jesse Coe, Shibom Basu, Thomas Grant, Matthew H. Seaberg, Raymond G. Sierra, Mark S. Hunter, Petra Fromme, Raimund Fromme, Denis L. Rousseau, Syun-Ru Yeh
Cytochromecoxidase (CcO) is a large membrane-bound hemeprotein that catalyzes the reduction of dioxygen to water. Unlike classical dioxygen binding hemeproteins with a hemebgroup in their active sites, CcO has a unique binuclear center (BNC) comprise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbcd7709f1190e865d64faa663099c2
https://doi.org/10.1101/2023.05.08.539888
https://doi.org/10.1101/2023.05.08.539888
Autor:
Elyse A. Schriber, Daniel W. Paley, Robert Bolotovsky, Daniel J. Rosenberg, Raymond G. Sierra, Andrew Aquila, Derek Mendez, Frédéric Poitevin, Johannes P. Blaschke, Asmit Bhowmick, Ryan P. Kelly, Mark Hunter, Brandon Hayes, Derek C. Popple, Matthew Yeung, Carina Pareja-Rivera, Stella Lisova, Kensuke Tono, Michihiro Sugahara, Shigeki Owada, Tevye Kuykendall, Kaiyuan Yao, P. James Schuck, Diego Solis-Ibarra, Nicholas K. Sauter, Aaron S. Brewster, J. Nathan Hohman
Publikováno v:
Nature, vol 601, iss 7893
Nature
Nature
Inorganic–organic hybrid materials represent a large share of newly reported structures, owing to their simple synthetic routes and customizable properties1. This proliferation has led to a characterization bottleneck: many hybrid materials are obl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46eb613642d78d3912b2c3aca41b62d
https://doi.org/10.1038/s41586-021-04218-3
https://doi.org/10.1038/s41586-021-04218-3