Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Raymond F. Lum"'
Autor:
James R. Cerhan, Kirsten A. Pfeiffer, Blanche Woehl, Linda Merlino, Lindsey A. Criswell, Michael F. Seldin, Ted R. Mikuls, Raymond F. Lum, Kenneth G. Saag
Publikováno v:
Annals of the Rheumatic Diseases. 65:1163-1167
Objective: To determine whether the impact of tobacco exposure on rheumatoid arthritis (RA) risk is influenced by polymorphisms at the HLA-DRB1 and glutathione S-transferase M1 ( GSTM1 ) loci. Methods: Subjects were participants from a case-control s
Autor:
Peter K. Gregersen, Kirsten A. Pfeiffer, Raymond F. Lum, Lindsey A. Criswell, Ward A. Ortmann, Kathy L. Moser, Bonnie Gonzales, Victoria E.H. Carlton, Jill Novitzke, Timothy W. Behrens, Marlena Kern, Annette Lee, Wentian Li, Ann B. Begovich
Publikováno v:
The American Journal of Human Genetics. 76(4):561-571
Autoimmune disorders constitute a diverse group of phenotypes with overlapping features and a tendency toward familial aggregation. It is likely that common underlying genes are involved in these disorders. Until very recently, no specific alleles--a
Autor:
Michael F. Seldin, Mark H. Wener, Wentian Li, Claire Bombardier, Marlena Kern, Franak Batliwalla, Elaine F. Remmers, Lindsey A. Criswell, Elena Massarotti, Daniel L. Kastner, Michael H. Weisman, Patricia Irigoyen, Annette Lee, Peter K. Gregersen, Raymond F. Lum
Publikováno v:
Arthritis & Rheumatism. 52:3813-3818
Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). Methods We studied 1,723 Caucas
Autor:
Kevin N. Turner, S. Louis Bridges, Raymond F. Lum, Hemant K. Tiwari, Jeffrey C. Edberg, Yuanqing Zhu, Jinyi Wang, Blanche Woehl, Larry W. Moreland, Robert P. Kimberly, Michael F. Seldin, Lindsey A. Criswell
Publikováno v:
Arthritis & Rheumatism. 50:2750-2756
Objective To examine the roles of specific genetic polymorphisms as predictors of response to treatment of early rheumatoid arthritis (RA). Methods Subjects included 457 patients with early RA (duration of ≤3 years) who participated in a randomized
Autor:
Jennifer D. Gorman, John J. Chen, Glenys Thomson, Maria E. Suarez-Almazor, Raymond F. Lum, Lindsey A. Criswell
Publikováno v:
Arthritis & Rheumatism. 50:400-412
Objective The strongest known genetic association in rheumatoid arthritis (RA) is with HLA–DRB1 alleles that share a similar amino acid sequence, termed the shared epitope (SE). Although many studies have examined the association of the SE with dis
Autor:
Salvatore Albani, Leigh F. Callahan, Aarti Damle, Ronald L. Wilder, Raymond F. Lum, S. Louis Bridges, Xiangli Xiao, Daniel O. Clegg, Donald J. Flemming, Wei V. Chen, Peter K. Gregersen, Daniel L. Kastner, Harry W. Schroeder, J. Lee Nelson, Christopher I. Amos, Mark H. Wener, Damini Jawaheer, Ryk Ward, Richard M. Pope, Carol J. Etzel, Lindsey A. Criswell, Russell Shigeta, Dong Chen, M. Kern, Michael F. Seldin, David S. Pisetsky, Joanita Monteiro, Theodore Pincus
Publikováno v:
Arthritis & Rheumatism. 48:906-916
Objective A number of non-HLA loci that have shown evidence (P < 0.05) for linkage with rheumatoid arthritis (RA) have been previously identified. The present study attempts to confirm these findings. Methods We performed a second genome-wide screen
Autor:
Erin Peden, Michael F. Seldin, Lindsey A. Criswell, A. Parsa, Victoria A. Seligman, Hongzhe Li, Jean L. Olson, Raymond F. Lum
Publikováno v:
Genes & Immunity. 3:S42-S46
Angiotensin II is a strong candidate for the perpetuation of autoimmunity, nephritis and visceral damage in systemic lupus erythematosus (SLE). Our goal was to determine whether angiotensin-converting enzyme (ACE) gene polymorphisms are associated wi
Autor:
Victoria A. Seligman, Raymond F. Lum, Doris Lin, Sven E. Inda, Hongzhe Li, Lindsey A. Criswell, Charlyn Suarez, Jean L. Olson, Michael F. Seldin
Publikováno v:
Arthritis & Rheumatism. 44:618-625
Objective To determine whether inheritance of Fcγ receptor (FcγR) alleles conferring lower affinity for IgG binding increases the risk of developing lupus nephritis. Methods We compared the frequency of low-affinity alleles of two FcγR polymorphis
Autor:
K. E. Taylor, Talmadge E. King, Lindsey A. Criswell, Raymond F. Lum, Joanne Nititham, S. Louis Bridges, Brent W. Kinder, Jeffrey C. Edberg, Michelle M. Freemer
Publikováno v:
Arthritis and rheumatism. 56(8)
Objective To define the contribution of polymorphisms in genes encoding tumor necrosis factor (TNF), mannose-binding lectin (MBL), and Fcγ receptor IIa (FCGR2A) as well as clinical factors, to the development of pneumonia in patients with systemic l
Autor:
Franak Batliwalla, Elena Massarotti, Annette Lee, Michael H. Weisman, Houman Khalili, Frederick Wolfe, Peter K. Gregersen, Elizabeth W. Karlson, Hye-Soon Lee, Lindsey A. Criswell, Marlena Kern, Claire Bombardier, Patricia Irigoyen, Raymond F. Lum, Robert Vlietinck
Publikováno v:
Arthritis and rheumatism. 56(6)
Objective Recently, Swedish members of the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) provided evidence that smoking may trigger RA-specific immune reactions to citrullinated protein in carriers of HLA–DR shared epitope alleles. I