Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Raymond E. Meyn"'
Autor:
Yuying Liu, Weihe Zhang, Ting Niu, Lawrence H. Cheung, Anupama Munshi, Raymond E. Meyn, Jr., Michael G. Rosenblum
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 2, Pp 125-135 (2006)
GrB/scFvMEL, a fusion protein composed of human granzyme B (GrB) and the single-chain antibody scFvMEL, targets melanoma gp240 antigen and exerts impressive cytotoxic effects by inducing apoptosis. We evaluated the effects of GrB/scFvMEL on chemother
Externí odkaz:
https://doaj.org/article/f041274ac6364b4287e61f0ac3b47960
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Assessment of the degree of synergy between cisplatin and MK-1775 in HN30 (wild-type TP53) and HN31 (mutant TP53) HNSCC cells respectively using the Chou and Talalay method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6352838fedef24046c6d1458ef5d2e
https://doi.org/10.1158/1535-7163.22503727.v1
https://doi.org/10.1158/1535-7163.22503727.v1
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Supplemental Figure 2. IR triggers a temporary, reversible perturbation in cellular reducing potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c75a61023cff22cc657ed7030da2603
https://doi.org/10.1158/1535-7163.22504008.v1
https://doi.org/10.1158/1535-7163.22504008.v1
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Supplemental figure legends - detailed text
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c686fafbd9ed69f7b7fb8a0dc330a4
https://doi.org/10.1158/1535-7163.22503993
https://doi.org/10.1158/1535-7163.22503993
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Determination of drug synergy by the combination-index and isobologram analyses using the CalcuSyn software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b6583d3f2e7dbca8d53f20c5eca8
https://doi.org/10.1158/1535-7163.22503718.v1
https://doi.org/10.1158/1535-7163.22503718.v1
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Ionizing radiation is the primary nonsurgical treatment modality for solid tumors. Its effectiveness is impacted by temporal constraints such as fractionation, hypoxia, and development of radioresistant clones. Biomarkers of acute radiation response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155fe6b3fbb2c2132c090a2ce93946b6
https://doi.org/10.1158/1535-7163.c.6537585.v1
https://doi.org/10.1158/1535-7163.c.6537585.v1
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Supplemental Figure 6. Loss of p53 function results in decreased radiosensitivity in HNSCC cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a49599bad04359f166e1aa153c8ee76
https://doi.org/10.1158/1535-7163.22503996.v1
https://doi.org/10.1158/1535-7163.22503996.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
The Wee-1 inhibitor, MK-1775 Synergizes with cisplatin in vitro in established HNSCC cell lines with known TP53 mutational status; Dual phospho-H3 staining and PI flow cytometric analysis (FACS); The synergy between cisplatin and MK-1775 in HNSCC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872ee87af6f3bd14707abe7cf9ba62ff
https://doi.org/10.1158/1535-7163.22503730
https://doi.org/10.1158/1535-7163.22503730
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Supplemental Figure 1. Metabolic inhibition and exogenous ROS perturb cellular reducing potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4a2325d2b51dd300013168cb847ef3
https://doi.org/10.1158/1535-7163.22504011.v1
https://doi.org/10.1158/1535-7163.22504011.v1
Autor:
Stephen Y. Lai, James A. Bankson, Clifton D. Fuller, Raymond E. Meyn, Jeffrey N. Myers, Laurence E. Court, Lei Feng, Tongtong Lu, Heath D. Skinner, Yunyun Chen, Vlad C. Sandulache
Supplemental Figure 5. Acute IR effects on reducing potential and lactate can be used to detect intrinsic radioresistance driven by loss of p53 activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce2cf74232dce4322c517e2d30bdab6
https://doi.org/10.1158/1535-7163.22503999
https://doi.org/10.1158/1535-7163.22503999