Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Raymond E. Gibson"'
Autor:
Pradip K. Majumder, Peter R. Strack, Giulio F. Draetta, Edwin A. Clark, Christopher Winter, Domenico Coppola, Timothy Yeatman, Carolyn Buser, Raymond E. Gibson, John F. Reilly, Giuseppe Mesiti, Shailendra Patel, Jennifer Tammam, Saverio Giampaoli, Timothy Sullivan, Christopher Ware, Christopher T. Winkelmann, Clay L. Efferson
Supplementary Figures 1-3, Tables 1-2 from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ed2415b597b108860c97ced4978686
https://doi.org/10.1158/0008-5472.22386984
https://doi.org/10.1158/0008-5472.22386984
Autor:
Chang Paik, William C. Eckelman, Toru Komai, W. J. Rzeszotarski, Raymond E. Gibson, J. Krijn Mazaitis, Richard C. Reba, Victor Jiang
Publikováno v:
Principles of Radiopharmacology ISBN: 9780429288760
Principles of Radiopharmacology
Principles of Radiopharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a91b003675f7e7375e30ff779132d20
https://doi.org/10.1201/9780429288760-3
https://doi.org/10.1201/9780429288760-3
Autor:
J. Krijn Mazaitis, William C. Eckelman, W. J. Rzeszotarski, Raymond E. Gibson, Toru Komai, Victor Jiang, Richard C. Reba, Chang Paik
Publikováno v:
Principles of Radiopharmacology ISBN: 9780429288715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7d95c76a7d09de53842ef010aa7a60
https://doi.org/10.1201/9780429288715-13
https://doi.org/10.1201/9780429288715-13
Autor:
Hisashi Ohta, Sandra M. Sanabria-Bohórquez, Michael F. Egan, Satoshi Ozaki, Guy Bormans, Kerry Riffel, William Cho, Marleen Depré, Shailendra Patel, Wai-Si Eng, Jacquelynn J. Cook, Tom Reynders, Raymond E. Gibson, Stephen Krause, Koen Van Laere, Christine Ryan, Sheng Bi, Stacey O'Malley, Osamu Okamoto, Eric D. Hostetler, Richard Hargreaves, Hiroshi Kawamoto, Aniket Joshi, Inge De Lepeleire, Tjibbe de Groot, H. Donald Burns, Jan de Hoon
Publikováno v:
NeuroImage. 68:1-10
Antagonism of the central opioid receptor like-1 receptor (ORL1) has been implicated in cognition, and has been a focus of drug discovery efforts to ameliorate the cognitive deficits that remain during the stable treatment of schizophrenia with curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75efc34d85dc68330a38fb08b31a4f83
https://doi.org/10.1016/j.neuroimage.2012.11.053
https://doi.org/10.1016/j.neuroimage.2012.11.053
Autor:
Raymond E. Gibson
Publikováno v:
Molecular Imaging and Biology. 13:594-598
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec7e05b88b6a4870789c2560fd3de073
https://doi.org/10.1007/s11307-011-0492-4
https://doi.org/10.1007/s11307-011-0492-4
Autor:
Raymond E. Gibson, Christopher T. Winkelmann, Christopher Ware, Domenico Coppola, Pradip K. Majumder, Christopher Winter, Edwin A. Clark, Peter Strack, Jennifer Tammam, Timothy Sullivan, Clay L. Efferson, Giuseppe Mesiti, Saverio Giampaoli, Shailendra Patel, Carolyn A. Buser, John F. Reilly, Timothy J. Yeatman, Giulio Draetta
Publikováno v:
Cancer Research. 70:2476-2484
ERBB2/neu and Notch signaling are known to be deregulated in many human cancers. However, pathway cross-talk and dependencies are not well understood. In this study, we use an ERBB2-transgenic mouse model of breast cancer (neuT) to show that Notch si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecb7da0b6f9b91edfff25fa32f17082
https://doi.org/10.1158/0008-5472.can-09-3114
https://doi.org/10.1158/0008-5472.can-09-3114
Autor:
Sandra M. Sanabria-Bohórquez, J. N. de Hoon, K. Van Laere, Richard Hargreaves, Raymond E. Gibson, Spencer J. Tye, Leslie J. Street, Ruth M. McKernan, I De Lepeleire, Robert W. Carling, Keith A. Wafford, Andrew Pike, John R. Atack, Guy Bormans, Christine Ryan, David James Hallett, HD Burns, M. G Murphy, Wai-Si Eng, A. Van Hecken, G. R. Dawson
Publikováno v:
Journal of Psychopharmacology. 25:329-344
In the accompanying paper we describe how MRK-409 unexpectedly produced sedation in man at relatively low levels of GABAA receptor occupancy (∼10%). Since it was not clear whether this sedation was mediated via the α2/α3 or α1 GABAA subtype(s),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea0a5ae22a6d2851dd26b1e9a8bbbb4
https://doi.org/10.1177/0269881109354928
https://doi.org/10.1177/0269881109354928
Autor:
Sandra Sanabria, Laura Vessy, H. Donald Burns, Jean-Claude Baron, Richard Hargreaves, Michael L. Schrag, José M. Vega, Robert F. Dannals, Raymond E. Gibson, John S. Beech, Dean F. Wong, John R. Atack, Wai Si Eng, Ruth M. McKernan, Franklin I. Aigbirhio, Tim D. Fryer, Paul Scott-Stevens, Bindi Sohal, Christine Ryan, Yun Zhou
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 332:17-25
The GABA(A) receptor alpha2/alpha3 subtype-selective compound 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023; also known as MK-0777) is a triazolopyridazine that has similar,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f325d96a51632434ec234c4602261192
https://doi.org/10.1124/jpet.109.157909
https://doi.org/10.1124/jpet.109.157909
Autor:
Obinna Ndubizu, Raymond E. Gibson, H. Donald Burns, Shil Patel, Terence G. Hamill, Ashok Chaudhary, Richard Hargreaves
Publikováno v:
Molecular Imaging and Biology. 7:314-323
Use of mGluR5 receptor radiotracers to determine whether an in vitro binding assay is able to predict how good a radiotracer is likely to be in imaging receptor in the central nervous system (CNS) via positron emission tomography (PET).Saturation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487244054123ffcb38593885a4f20b18
https://doi.org/10.1007/s11307-005-0005-4
https://doi.org/10.1007/s11307-005-0005-4
Autor:
Raymond E. Gibson
Publikováno v:
Molecular Imaging and Biology. 15:644-646
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4b17ba7ffaf5f464e380a636df45015
https://doi.org/10.1007/s11307-013-0681-4
https://doi.org/10.1007/s11307-013-0681-4