Zobrazeno 1 - 2
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pro vyhledávání: '"Raymond Dokhan"'
Autor:
Xuan Wang, Agnès Pelé-Tounian, Bruno Pfeiffer, Sylvie Marc, Frédéric Rondu, Alain Ktorza, Beatrice Guardiola-Lemaitre, Luc Pénicaud, Dominique Manechez, Pierre Renard, Azzdine Lamouri, Estera Touboul, Raymond Dokhan, Jean-Jacques Godfroid
Publikováno v:
British Journal of Pharmacology. 124:1591-1596
Recent data suggest that some imidazoline derivatives can lower plasma glucose in experimental animal models of diabetes. We studied the activity of an imidazoline S-22068, in rat model of non-insulin-dependent diabetes mellitus (NIDDM) produced with
Autor:
Elisabeth Laurent, Philippe Maillet, Raymond Dokhan, Akram Talab, Roland Ollivier, Youssef El Ahmad, and Gilles Tran, Jean François Teste
Publikováno v:
Journal of Medicinal Chemistry. 40:952-960
A series of 1-(benzocycloalkyl)-4-(benzamidolkyl)piperazine derivatives was prepared in order to obtain compounds with a high affinity and selectivity for 5-HT1A receptors. The modifications of aromatic substituents, the length of the alkyl chain, an