Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Raymond Diokno"'
Autor:
Scott Jacobson, Dennis X. Hu, Cesar Meleza, Mikhail Zibinsky, Ashkaan Younai, Erin Riegler, Omar Robles, Jenny McKinnell, Emily Karbarz, Paul D. Kassner, Lisa A. Marshall, Maureen Kay Reilly, David Chian, Gene Cutler, David J. Wustrow, Dirk G. Brockstedt, Hunter P. Shunatona, Raymond Diokno, Angela Wadsworth, John M. Ketcham, Oezcan Talay, Jeffrey J. Jackson
Publikováno v:
Journal of Medicinal Chemistry. 63:8584-8607
The C-C chemokine receptor 4 (CCR4) is broadly expressed on regulatory T cells (Treg) as well as other circulating and tissue-resident T cells. Treg can be recruited to the tumor microenvironment (TME) through the C-C chemokines CCL17 and CCL22. Treg
Autor:
Deepa Pookot, Scott Jacobson, John M. Ketcham, David Chian, Emily Karbarz, Dennis X. Hu, James Ross Walker, Gene Cutler, Ashkaan Younai, Mikhail Zibinsky, Raymond Diokno, David J. Wustrow, Betty Abraham, Angela Wadsworth, Maureen Kay Reilly, Cesar Meleza, Jenny McKinnell, Jeffrey J. Jackson, Abood Okal, Paul D. Kassner, Lisa A. Marshall, Oezcan Talay, Berenger Biannic, Bui Minna H T, Hilary Plake Beck, Hunter P. Shunatona, Omar Robles
Publikováno v:
Journal of Medicinal Chemistry. 62:6190-6213
Recruitment of suppressive CD4+ FOXP3+ regulatory T cells (Treg) to the tumor microenvironment (TME) has the potential to weaken the antitumor response in patients receiving treatment with immuno-oncology (IO) agents. Human Treg express CCR4 and can
Autor:
Jeffrey J, Jackson, John M, Ketcham, Ashkaan, Younai, Betty, Abraham, Berenger, Biannic, Hilary P, Beck, Minna H T, Bui, David, Chian, Gene, Cutler, Raymond, Diokno, Dennis X, Hu, Scott, Jacobson, Emily, Karbarz, Paul D, Kassner, Lisa, Marshall, Jenny, McKinnell, Cesar, Meleza, Abood, Okal, Deepa, Pookot, Maureen K, Reilly, Omar, Robles, Hunter P, Shunatona, Oezcan, Talay, James R, Walker, Angela, Wadsworth, David J, Wustrow, Mikhail, Zibinsky
Publikováno v:
Journal of medicinal chemistry. 62(13)
Recruitment of suppressive CD4
Autor:
Heinz E. Moser, Kenneth B. Wlasichuk, George H. Miller, Eliana Saxon Armstrong, Paola Dozzo, Sara Lopez, Raymond Diokno, Micah J. Gliedt, Rowena D. Matias, Lee Ann Feeney, Martin S. Linsell, Darin Hildebrandt, M. A. Gómez, Adam Aaron Goldblum, James B. Aggen, Aya Kubo
Publikováno v:
Antimicrobial agents and chemotherapy. 54(11)
Aminoglycosides (AGs) are highly potent, broad-spectrum antibiotics used for treating serious bacterial infections. They are a well-established class of antibacterials that act by binding to the A-site of the bacterial ribosome and interfering with n